Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd... حسب Bo Peng (273834)

"…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …"

Image 4_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf حسب Yufei Li (433737)

"…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…"

This is raw data of NF-κB real-time PCR. حسب Farzad Nasri (8941850)

"…IFN-β in contrast to Vit D decreased <i><i>Gal-9</i></i> gene expression. <i>β-<i>catenin</i></i> gene expression increased after IFN-β or Vit D treatment. …"

Supplementary file 1_Transcriptome-wide N6-methyladenosinem modifications analysis of chicken cecum in responding to Campylobacter jejuni inoculation.zip حسب Yanan Zhao (3132906)

"…</p>Results<p>In the S group, the level of proinflammatory cytokines (IL-8, IL-1β, IL-18, TNF-α, IL-17A) and global RNA methylation were significantly decreased (P < 0.05). A total of 30,427 and 30,367 m⁶A peaks were identified in R and S groups, which were primarily located in 3'UTR and CDS regions. …"

Parameter optimal analysis. حسب Wanjun Zhang (496858)

"…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …"

Data Sheet 1_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx حسب Xinxin Wang (134010)

"…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …"

Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx حسب Yonghui Zhang (279832)

"…EA treatment (25 mg/kg) markedly inhibited tumour growth in vivo in a xenograft model; both tumour weight and tumour volume decreased by more than 60% without significantly affecting the body weight of tumour-bearing mice.…"

Table 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... حسب Bo Peng (273834)

"…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …"

Image 4_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

"…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"

Image 2_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf حسب Yufei Li (433737)

"…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…"

Image1_Comprehensive analysis of Hibisci mutabilis Folium extract’s mechanisms in alleviating UV-induced skin photoaging through enhanced network pharmacology and experimental vali... حسب Wenyuan Chen (1770583)

"…In vitro experiments showed that EHMF significantly reduced UV-induced inflammatory factors in HaCaT cells and improved cell survival rates. …"

Image 7_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

"…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"

Experimental irrigation scheme design. حسب Wanjun Zhang (496858)

"…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …"

Image 9_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

"…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"

Image3_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif حسب Zi Yang (276531)

"…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …"

Transcriptomic analysis of AMPK and HZL-1 mutants reveals widespread gene expression differences predominantly in the germ line. حسب Sabih Rashid (5618807)

"…<b>C)</b> (Top) Venn diagram comparing genes with decreased expression in <i><i>hzl-1; aak(0)</i></i> dauer vs. …"

Different controller performance indicators 2. حسب Wanjun Zhang (496858)

"…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …"

Image4_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif حسب Zi Yang (276531)

"…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …"

Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx حسب Yajie Hu (550783)

"…We observed that the level of IP-10, as well as the TLR3-TRIF-TRAF3-TBK1-NF-κB and RIG-I/MDA5-MAVS-TRAFS-TBK1-NF-κB pathways, which are the upstream of IP-10, were significantly elevated during the course of CV-A16 infection. …"

Image 1_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf حسب Yufei Li (433737)

"…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…"