Data Sheet 5_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

Loss function variation curve. by Chunhua Yang (346871)

“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”

Table 1_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Presentation 1_Global patterns of change in the burden of malnutrition in older adults from 1990 to 2021 and the forecast for the next 25 years.pdf by Le Li (356426)

“…Background<p>Malnutrition poses a significant public health challenge, particularly as the global population ages. …”

Table 1_Coptis japonica Makino ethanol extracts attenuates cancer cachexia induced muscle and fat wasting through inhibition of the STAT3 signaling pathway.docx by Yo Sep Hwang (17967916)

“…Our results demonstrated that CJME significantly decreased the mRNA and protein levels of muscle-specific E3 ubiquitin ligases Atrogin-1 and MuRF1 in myotubes exposed to CT26 CM. …”

Data Sheet 2_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.xlsx by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Supplementary Material for: Acute interstitial nephritis associated to Pertussis infection: a case report and review of the literature by figshare admin karger (2628495)

“…Initial laboratory findings revealed mild leukocytosis and significantly elevated serum creatinine (5.17 mg/dL), with urinalysis showing leukocyturia and proteinuria. …”

Data Sheet 2_Pandan–vanilla rotation mitigates Fusarium wilt disease in vanilla: insights from rhizosphere microbial community shifts.xlsx by Shan Hong (1938337)

“…Crop rotation significantly increased fungal diversity and richness. …”

Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction by Zhihui Liu (95891)

“…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …”

Table 3_High humidity environment increases FBG by impairing the intestinal barrier.xlsx by Yao Wang (102387)

“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”

Sex-specific responses of mosquitoes to <i>Bti</i> pesticide and odonate predators by Jaclyn Everly (22623200)

“…We found that Bti reduced larval abundance by ~90% within 48 hours but did not induce an overcompensatory response in adult production or fitness. Predators had no significant effect on larvae within 48 hours, but they did have sex-specific effects on the abundance and size of adult mosquitoes. …”

Supplementary Materials - Figure by Shaojie Zhang (20807333)

“…<p dir="ltr">Exposure to hypobaric hypoxia during rapid ascent to high altitudes significantly impacts intestinal barrier function. Goblet cells, as one of the primary cell types in the intestinal mucosa, play a crucial role in maintaining this barrier. …”

Supplementary file 3_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf by Yanling Wen (552195)

“…</p>Results<p>Our analysis revealed that the proportion of CCR7⁺ Tregs decreased as the disease advanced, while the cell proportion of HLA_DR⁺ regs escalated with the severity of the disease. …”

Video 1_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Image 2_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Type level landscape index changes in 1990-2020. by Chao Ma (207385)

“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”

Characteristics comparison of related literature. by Bin Zhao (276445)

“…<div><p>Capturing congestion propagation among different facilities at intersections in dynamic stochastic traffic environments poses significant challenges, particularly under oversaturated conditions. …”

Data Sheet 9_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Supplementary file 1_A cross-sectional study of the current status of psychological health and its correlation with academic performance in medical students: taking medical student... by Han Chunhong (20703500)

“…</p>Conclusion<p>The undergraduates face significant challenges in depression, anxiety, insomnia, and perceived stress, and these have negative effects on their academic performances; in particular, the depressive symptoms and perceived stress can significantly reduce their academic performances. …”

Table 3_Inequalities and age-period-cohort effects of global and regional burden for interstitial lung disease and pulmonary sarcoidosis: based on Global Burden of Disease study 20... by Lei Zhang (38117)

“…Background<p>Interstitial lung disease (ILD) and pulmonary sarcoidosis pose significant disease burdens on a global scale.</p>Methods<p>The underlying data was derived from the Global Burden of Disease (GBD) 2021 database. …”