Data Sheet 4_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.pdf by Yi-Ming Ren (555968)

“…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …”

Table 1_Electroacupuncture improves scopolamine hydrobromide induced dry eye in mice via inhibiting ocular surface inflammation and regulating the HMGB1-related signaling pathways.... by Xia Wu (203682)

“…The levels of HMGB1, RAGE, TLR2, TLR4, and IL-6 were significantly decreased while IL-10 level was significantly increased after EA treatment, indicating that EA may improve dry eye surface inflammation by inhibiting HMGB1-related signaling pathways.…”

Table 1_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.xlsx by Zhiyong Wang (313131)

“…Mantel test analysis revealed that soil total potassium (TK), soil organic carbon, total nitrogen, and several other metals, including zinc, niobium, titanium (Ti), manganese, rubidium, barium, potassium, cobalt, gallium (Ga), Se, chromium (Cr), vanadium, and copper were significantly and positively correlated with microbial community composition across all soil samples. …”

Table 2_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.docx by Zhiyong Wang (313131)

“…Mantel test analysis revealed that soil total potassium (TK), soil organic carbon, total nitrogen, and several other metals, including zinc, niobium, titanium (Ti), manganese, rubidium, barium, potassium, cobalt, gallium (Ga), Se, chromium (Cr), vanadium, and copper were significantly and positively correlated with microbial community composition across all soil samples. …”

Data Sheet 1_Daily online adaptation enhances target coverage in prostate cancer radiotherapy: a retrospective analysis.pdf by Hanna Malygina (22545980)

“…Interquartile ranges decreased across all metrics.</p>Conclusions<p>Adaptation significantly improved target dose metrics compared to non-adapted plans, without compromising organs-at-risk sparing. …”

Data Sheet 1_Effect of NR1D1 on the proliferation and differentiation of yak skeletal muscle satellite cells.pdf by Yuqi Zhe (20107152)

“…Compared with those in the control group, the expression levels of proliferation marker genes KI-67, CYCLIND1, and CYCLINA were significantly inhibited after NR1D1 overexpression, which was also supported by the CCK-8 test, whereas differentiation marker genes MYOD, MYOG, and MYF5 were significantly inhibited. …”

Supplementary Material for: Comparing Two Oral Immunotherapy Strategies for Sesame Allergy: Baked Goods with Sesame Paste Versus Crushed Sesame Seeds by figshare admin karger (2628495)

“…For both the baked goods and the seeds group, likelihood of severe reactions significantly decreased over time. Conclusion: A modified sesame desensitization protocol using baked sesame paste can be safely used in children with sesame allergy.…”

Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif by Yaqi Cui (10798865)

“…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …”

Supplemental_Figure_of_Imeglimin_ameliorate_SA-AKI by Hiroyasu Goto (12227927)

“…Serum ALT levels were not significantly different before and after E. coli challenge between the Ime and Veh groups. …”

Table1_Around the clock: unveiling giraffe rest-activity rhythms and social dynamics.docx by Hanna Mebus (19961244)

“…The presence of a male giraffe during one intervention phase significantly altered diurnal activity patterns, increasing standing behaviors and decreasing feeding time. …”

Graphical Abstract. by Furkan Özdemir (21560297)

“…Peak VO₂ (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”

PONE-Dataset. by Furkan Özdemir (21560297)

“…Peak VO₂ (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”

Demographic characteristics of groups. by Furkan Özdemir (21560297)

“…Peak VO₂ (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”

Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets by Karl Knipper (15016346)

“…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …”

Supplementary Material for: The effectiveness of regionalization of perinatal care and specific facility-based interventions: A systematic review by Ali A.A. (19754238)

“…Results: Implementation of regionalization programs significantly decreased maternal and perinatal mortality. …”

Image 9_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

“…The curcumin-loaded nanoliposomes had inhibitory effect on A. alstroemeriae, in vitro experiment showed that the minimum fungicidal concentration (MIC) of curcumin-loaded nanoliposomes against the hyphae growth of A. alstroemeriae was 10 μmol/L, and 4MIC treatment significantly reduced the occurrence of black rot in citrus fruit in vivo test. …”

Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Image 8_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

“…The curcumin-loaded nanoliposomes had inhibitory effect on A. alstroemeriae, in vitro experiment showed that the minimum fungicidal concentration (MIC) of curcumin-loaded nanoliposomes against the hyphae growth of A. alstroemeriae was 10 μmol/L, and 4MIC treatment significantly reduced the occurrence of black rot in citrus fruit in vivo test. …”

Image 4_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tiff by Asma Bibi (12057986)

“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”

Image 3_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif by Asma Bibi (12057986)

“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”