Image 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg by Xiao-Ting Luo (20836646)

“…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…”

Presentation_1_The impact of challenge and hindrance stressors on knowledge hiding: the mediating role of job crafting and work withdrawal.pdf by Le Wang (165105)

“…The findings indicate that both challenge and hindrance stressors significantly increase knowledge hiding, with hindrance stressors exerting a more pronounced effect. …”

Data Sheet 9_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Image 5_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

“…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”

Data Sheet 4_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.csv by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Image 6_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”

Reinforcement Learning for Assessing Route Instruction Usability in Complex Indoor Spaces by Reza Arabsheibani (14244716)

“…Our results show that RL agents successfully learn to navigate even with incomplete instructions, significantly outperforming random agents. Agents trained on diverse environments generalize well to novel settings, although performance decreases with higher environmental complexity and finer-grained instruction grammars when instructions are incomplete. …”

Soil viral and microbial interactions facilitate microbial necromass carbon accumulation in the semiarid typical steppe under altered precipitation_Research Data by Cui Han (15263150)

“…The results showed that decreased precipitation significantly reduced microbial necromass carbon (BNC, MNC, and BNC/MNC) and their relative contributions to SOC (BNC/SOC and MNC/SOC), whereas increased precipitation had relatively weaker effects. …”

Error-Bar graph. by Haichao Li (225035)

“…Results show that SIDFM reduces navigation errors by 12.09% at low acceleration and 11.43% at high acceleration while also significantly decreasing positioning errors. These improvements enhance the stability, precision, and safety of AGVs in dynamic manufacturing environments. …”

Image 1_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif by Tengfei Tian (1793545)

“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”

Data Sheet 1_α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach.docx by Aimin Cai (6190532)

“…</p>Results<p>The results of the study demonstrated that α-MT significantly reduced the urinary excretion of albumin and creatinine, improved kidney function, and decreased renal fibrosis in db/db mice. …”

Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”

Data Sheet 1_Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae.pdf by Lisa Zierke (20682053)

“…Infections of Galleria mellonella larvae showed a significantly decreased virulence potential of the CPS-deficient mutant.…”

Image 2_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

“…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”

Image 2_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”

Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents by Yujuan Li (554062)

“…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …”

Supplementary Material for: A common variant in NID1 gene associated with the prognosis of heart failure by figshare admin karger (2628495)

“…Western blot analysis demonstrated that the protein level of NID1 was significantly higher in the rs3738530-T allele compared to the A allele (P < 0.05). …”

Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Data Sheet 12_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”