Image 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”

Table 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”

Table 1_Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases.docx by Maria Dodina (20223012)

“…In the preclinical research phase, in vitro models complement in vivo models by reducing animal studies, decreasing costs, and shortening research timelines. …”

YOLOv8n detection results diagram. by Yaojun Zhang (389482)

“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”

Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel by Yuzhen Lu (4402591)

“…Loss of <i>MrGDH2</i> function resulted in significantly reduced virulence during both cuticle-passing and cuticle-bypassing infections but did not affect appressorium formation or cuticle penetration. …”

Image 1_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”

Dynamic window based median filtering algorithm. by Li Yuan (102305)

“…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …”

Image 7_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif by Chen Wang (88408)

“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”

Table 1_Correlation between changes of amino acid spectrum and alopecia in patients with obesity undergoing bariatric surgery: a prospective cohort study.docx by Tingwen Wang (3927815)

“…</p>Results<p>Among 67 patients analyzed, LSG significantly decreased serum concentrations of arginine, alanine, threonine, glutamic acid, branched-chain amino acids (valine, isoleucine, leucine), and aromatic amino acids (tyrosine, phenylalanine, tryptophan) (p < 0.05), while serine and glycine increased (p < 0.05). …”

Data for: Drought and temperature stresses impact pollen production and autonomous selfing in a California wildflower, Collinsia heterophylla by H. S. Arathi (22077395)

“…In nature, such responses will likely reduce available nutrition for pollinators through decreased flower and pollen production.</p><p>The included data file can be opened with any spreadsheet software including MS Excel or Google Sheets.…”

Image 4_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg by Aleksandr Berezovski (20548583)

“…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …”

YOLOv8n-BWG model structure diagram. by Yaojun Zhang (389482)

“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”

Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg by Wenqiao Jia (12356306)

“…</p>Conclusion<p>Our findings elucidate the molecular mechanism that PCP4 downregulation promotes PCa progression via Ca²⁺/CAMKK2/AMPK/AR pathway, highlighting its significance in CRPC development.</p>…”

Navigation error analysis. by Haichao Li (225035)

“…Results show that SIDFM reduces navigation errors by 12.09% at low acceleration and 11.43% at high acceleration while also significantly decreasing positioning errors. These improvements enhance the stability, precision, and safety of AGVs in dynamic manufacturing environments. …”

Supplementary file 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machi... by Zhiyuan Gong (51844)

“…Recovery analysis showed significantly reduced adaptive immune cells at 1 month, with partial recovery by 3 and 6 months. …”

Image 6_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”

Raw data WB.pdf by Grazia Serino (21164993)

“…Moreover, miR-369-3p significantly decreased the release of pro-inflammatory cytokine IL-8. …”

Image 2_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Base-case results. by Mingxi Xie (19812594)

“…Clinical findings have showed that deprescribing service significantly decreased inappropriate PPIs utilization. …”

Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg by Shenglan He (7641308)

“…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”