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21021
Table1_Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway.DOCX
Published 2025“…Astragaloside IV (AS-IV) is a saponin extract of the Astragalus which is widely used in the treatment of kidney disease. …”
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21022
Table 1_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”
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21023
Table 4_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”
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21024
Table 1_The improvement effect of insoluble dietary fiber of Polygonatum sibiricum on hyperlipidemia in high-fat diet mice via gut microbiota and metabolites.docx
Published 2025“…</p>Results<p>The results of the LIDF and HIDF showed that the PIDF treatment significantly alleviated the liver and kidney weight and body fat index. …”
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21025
Table 2_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”
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21026
Table 1_Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021.docx
Published 2025“…</p>Conclusion<p>Although the global burden of diarrhea has decreased significantly, it is still high in low-income countries and low- and medium-SDI areas, and newborns are at high risk. …”
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21027
Table 1_Epidemiological characteristics and trends of pre-hospital emergency care in Handan, China from 2011 to 2024.docx
Published 2025“…Over the past 14 years, Handan’s pre-hospital EMS demand increased significantly by 3.11-fold (p < 0.001). The percentages of EMS patients aged 61 to 70 and over 71 years old increased significantly (p < 0.01), in contrast, the percentage of EMS patients aged 21 to 30 and 31 to 40 years old decreased significantly (p < 0.01). …”
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21028
Table 1_Effects of perinatal nutrition supplementation and early weaning on serum biochemistry, metabolomics, and reproduction in yaks.docx
Published 2024“…Lipid transportation molecules apolipoprotein B100 and very low-density lipoprotein of SF and SW yaks were significantly increased along with the decreased lipid mobilization products non-esterified fatty acid and β-hydroxybutyric acid when compared to GF yaks at −15 and 30 d. …”
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21029
Table 1_Electroacupuncture improves scopolamine hydrobromide induced dry eye in mice via inhibiting ocular surface inflammation and regulating the HMGB1-related signaling pathways....
Published 2025“…The levels of HMGB1, RAGE, TLR2, TLR4, and IL-6 were significantly decreased while IL-10 level was significantly increased after EA treatment, indicating that EA may improve dry eye surface inflammation by inhibiting HMGB1-related signaling pathways.…”
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21030
Table 1_Circulating microRNA signatures as potential biomarkers differentiating diabetic, prediabetic, and healthy individuals.docx
Published 2025“…Still, consistent trend-level decreases in diabetes were observed for hsa-miR-4776-5p, hsa-miR-6778-3p, and hsa-miR-5002-3p, which were among the most upregulated in prediabetes vs. controls. …”
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21031
Presentation 1_Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice.zip
Published 2025“…These mice were fed with a high-fat diet for 9 weeks to induce inflammation. …”
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21032
DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF
Published 2024“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”
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21033
Image1_Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling.jpeg
Published 2024“…</p>Results<p>NAP recombinant spore treatment significantly reduced allergic symptoms and intestinal inflammation. …”
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21034
Effect of HPC silencing on phase-locking of PFC neurons to local theta.
Published 2025“…Percentage of neurons significantly phase-locked to PFC theta oscillations (4–12 Hz) in the sample <b>(A)</b> and choice phase <b>(B)</b> during light-off and light-on trials. …”
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21035
Table 1_Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice.docx
Published 2025“…These mice were fed with a high-fat diet for 9 weeks to induce inflammation. …”
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21036
Data Sheet 1_An active ingredient from the combination of Corydalis Rhizoma and Paeoniae Radix Alba relieves chronic compression injury-induced pain in rats by ameliorating AR/Mboa...
Published 2025“…</p>Results<p>The results demonstrated that YB60 significantly decreased inflammatory cytokine levels both in cellular models and rat serum, while concurrently elevating pain thresholds in CCI rats. …”
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21037
Data Sheet 1_Dendritic cells in the human vaginal mucosa can direct CD4+ T cell responses by expressing surface OX40L.pdf
Published 2025“…Neutralizing OX40L with anti-OX40L antibody significantly decreased the frequency of Th2-type CD4<sup>+</sup> T cells with a reduction of CD4<sup>+</sup> T cell proliferation, while increasing the frequency of IL - 10-producing CD4<sup>+</sup> T cell responses. …”
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21038
Data Sheet 2_Dendritic cells in the human vaginal mucosa can direct CD4+ T cell responses by expressing surface OX40L.pdf
Published 2025“…Neutralizing OX40L with anti-OX40L antibody significantly decreased the frequency of Th2-type CD4<sup>+</sup> T cells with a reduction of CD4<sup>+</sup> T cell proliferation, while increasing the frequency of IL - 10-producing CD4<sup>+</sup> T cell responses. …”
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21039
Mitigating toxicity of arsenic in sunflower (<i>Helianthus annuus</i> L.) with phosphate rock and farmyard manure using contrasting soil textures
Published 2025“…Plants were treated with As (60 and 120 mg kg<sup>−1</sup> soil), PR (5 and 20 g kg<sup>−1</sup> soil) and FYM (5 and 20% w/w) with a control. After sixteen weeks of growth period, results showed that As solubility decreased by 22.07–44.85% and 21.33–36.35% in sand, 17.55-45.80% and 30.83-45.98% in loam, while 22.81-36.89% and 20.92-42.41% in clay soils at As<b>-</b>60 and As<b>-</b>120, respectively with varied PR+FYM combinations compared to control. …”
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21040
Data Sheet 1_Strategies for enhancing yield and quality of forage-grain dual-purpose ratoon rice: role of first-season density and nitrogen management.docx
Published 2025“…Results showed that: Silage yield increased significantly with higher density and nitrogen input. …”