Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i> by Meng-Ru Guo (21375491)

“…Pathogenicity assays revealed that the deletion of <i>RNH2B</i> results in reduced virulence, whereas its overexpression leads to a complete loss of pathogenicity. Longitudinal tracking of fungal infection progression illustrated that mice lungs infected with <i>rnh2B</i>Δ mutants maintained a low yet stable fungal burden, in contrast to a significant reduction in fungal load observed in conjunction with <i>RNH2B</i> overexpression, ultimately leading to complete clearance. …”

Image 1_Effect of hypoxia-induced mIL15 expression on expansion and memory progenitor stem-like TILs in vitro.tif by Zhen Sun (269397)

“…RNA-Seq data revealed that in TIL-mIL15-IL2 cells, the expression of genes related to T cell differentiation and effector function, including PRDM1, ID2, EOMES, IFNG, GZMB, and TNF, were significantly decreased, whereas the expression of the memory stem-like T cell marker TCF7 was significantly increased. …”

Table 1_Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis.docx by Xuan Wu (126953)

“…Additionally, the percentage of peripheral B cells in the tacrolimus group decreased significantly after treatment (from 11.8 ± 4.7% to 9.4 ± 4.4%, P = 0.006). …”

Altitudinal patterns and drivers of moss plant traits in the genera Didymodon and Tortula in eastern Pamir Plateau, China by Zhang Yue (21347735)

“…With increasing altitude, Tortula exhibited a significant increase in leaf width and midrib width (P < 0.05), enhancing its light-harvesting capacity; whereas in Didymodon, plant height and stem diameter increased significantly (P < 0.05), while leaf width and midrib width decreased significantly (P < 0.05), indicating an adaptive strategy of strengthening structural rigidity and forming compact leaves to cope with high-altitude environments. …”

Image 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..tif by Felicia Menicucci (7495508)

“…The Rossa di Treviso Tardiva also exhibited a significant accumulation of polyphenols under red LEDs compared to white LEDs. …”

Image 3_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..jpeg by Felicia Menicucci (7495508)

“…The Rossa di Treviso Tardiva also exhibited a significant accumulation of polyphenols under red LEDs compared to white LEDs. …”

Table 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..docx by Felicia Menicucci (7495508)

“…The Rossa di Treviso Tardiva also exhibited a significant accumulation of polyphenols under red LEDs compared to white LEDs. …”

Sex-specific brain volume changes in ECM. by Alicia Comino Garcia Muñoz (22075399)

“…There is a significant interaction between the sex of the animal and the volume change of the anterior commissure (G). …”

Data Sheet 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..pdf by Felicia Menicucci (7495508)

“…The Rossa di Treviso Tardiva also exhibited a significant accumulation of polyphenols under red LEDs compared to white LEDs. …”

Image 2_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..tif by Felicia Menicucci (7495508)

“…The Rossa di Treviso Tardiva also exhibited a significant accumulation of polyphenols under red LEDs compared to white LEDs. …”

Table 2_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..docx by Felicia Menicucci (7495508)

“…The Rossa di Treviso Tardiva also exhibited a significant accumulation of polyphenols under red LEDs compared to white LEDs. …”

Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy by Tanvi Chokshi (12970453)

“…In multivariable analyses, RBP3 remained significantly associated with a DR progression and history of DME. …”

Table 1_Sitagliptin phosphate ameliorates chronic inflammation in diabetes mellitus via modulating macrophage polarization.docx by Xiaoxia Hu (170413)

“…Moreover, histological analysis showed that compared with the Control group, the size of visceral adipocytes, hepatocyte lipid deposition and the ratio of M1/M2 macrophage were higher in the DM group, which were reversed by Sitagliptin phosphate treatments (P<0.05), insulin treatments did not have a significant effect (P>0.05). Mechanistically, Western blot showed that compared with the normal group, HG upregulated the expression of mTORc1 protein, P-65 phosphorylation and P-65 protein expression in Raw264.7 cells (P<0.05), downregulated the expression of IKKβ (P<0.05) and PPAR-γ proteins (P<0.05), Sitagliptin phosphate and insulin treatments rescued these changes. …”

Table 1_Global, regional, and national trends in the incidence of pneumoconiosis among populations aged 20 and above from 1990 to 2021.xlsx by Qiyun Cheng (22074758)

“…Notably, the EAPC showed a statistically significant but very weak positive correlation with the 2021 Human Development Index (HDI) values.…”

Table 1_Lyophyllum decastes-derived polysaccharides alleviate DSS-induced colitis in mice by suppressing inflammation, enhancing intestinal barrier integrity, and restoring gut mic... by Eslam Ghaleb (21698810)

“…Additionally, LDP improved intestinal barrier function by reducing MPO activity and enhancing occludin and ZO-1 expression. 16S rRNA sequencing revealed a significant restoration of gut microbiota diversity, with an increase in beneficial bacteria Muribaculaceae, Lactobacillus, and Lachnospiraceae, and a reduction in pathogenic bacteria Escherichia-Shigella. these findings suggest that LDP exhibits therapeutic effects in DSS-induced colitis through anti-inflammatory properties, enhancement of intestinal barrier function, and modulation of gut microbiota. …”

Presentation 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.pptx by Hui Li (32376)

“…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …”

Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx by Ji Yang (114503)

“…Background<p>Current therapeutic options for inflammatory bowel disease (IBD) remain suboptimal due to limited efficacy, significant side effects, and high relapse rates, necessitating novel treatment strategies. …”

Table 1_Perception of health and illness and quality of life after total thyroidectomy for differentiated thyroid carcinoma: the PERSAM study.docx by Elena Groff (7446932)

“…Mental health: more information to patients decreases the degree of stress and promotes ‘positive’ emotions. …”