Addressing Imbalanced Classification Problems in Drug Discovery and Development Using Random Forest, Support Vector Machine, AutoGluon-Tabular, and H2O AutoML by Ayush Garg (21090944)

“…The important findings of our studies are as follows: (i) there is no effect of threshold optimization on ranking metrics such as AUC and AUPR, but AUC and AUPR get affected by class-weighting and SMOTTomek; (ii) for ML methods RF and SVM, significant percentage improvement up to 375, 33.33, and 450 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy, which are suitable for performance evaluation of imbalanced data sets; (iii) for AutoML libraries AutoGluon-Tabular and H2O AutoML, significant percentage improvement up to 383.33, 37.25, and 533.33 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy; (iv) the general pattern of percentage improvement in balanced accuracy is that the percentage improvement increases when the class ratio is systematically decreased from 0.5 to 0.1; in the case of F1 score and MCC, maximum improvement is achieved at the class ratio of 0.3; (v) for both ML and AutoML with balancing, it is observed that any individual class-balancing technique does not outperform all other methods on a significantly higher number of data sets based on F1 score; (vi) the three external balancing techniques combined outperformed the internal balancing methods of the ML and AutoML; (vii) AutoML tools perform as good as the ML models and in some cases perform even better for handling imbalanced classification when applied with imbalance handling techniques. …”

NIE ELISA results. by Jannet A. Tobon Ramos (20855642)

“…We compared the effectiveness of a single round of MDA with IDA or DA on hookworm and strongyloidiasis in PNG.…”

Kato Katz and PCR database 12 months collection. by Jannet A. Tobon Ramos (20855642)

“…We compared the effectiveness of a single round of MDA with IDA or DA on hookworm and strongyloidiasis in PNG.…”

Master database baseline, 4 weeks and 1 year. by Jannet A. Tobon Ramos (20855642)

“…We compared the effectiveness of a single round of MDA with IDA or DA on hookworm and strongyloidiasis in PNG.…”

PBMC T cell subsets vary between mock- and sequentially-infected mice. by Yuhao Li (1559569)

(a) Carbon emissions (%) as a function of temperature for the integrated and control systems. (b) Output mass of biochar (g) at various temperatures for the integrated and control... by Ning Zuo (17295415)

Sequential infection does not alter relative proportions of white blood cells. by Yuhao Li (1559569)

Sequential viral exposure shapes immune cell profiles in tissues. by Yuhao Li (1559569)

The impact of MDA on hookworm prevalence and intensity of infection stratified by treatment with IDA or DA. by Jannet A. Tobon Ramos (20855642)

Receiver operating characteristic curve for anti-NIE antibodies for <i>S. stercoralis.</i> by Jannet A. Tobon Ramos (20855642)

“…The seroprevalence increased with age and was significantly decreased following IDA treatment in each age group (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012851#pntd.0012851.g006" target="_blank">Fig 6</a>). …”

A working model for the RRSV Pns10-promoted RRSV infection in <i>N. lugens</i> through inducing NlNDUFS1-mediated mitochondrial apoptosis. by Lianshun Zheng (22086585)

“…This impairment of mitochondrial complex I activity results in a significant decrease of ATP production and an increase of mitochondrial ROS production, which causes mitochondrial apoptosis to facilitate RRSV infection in <i><i>N. lugens</i></i>.…”

3‑Furoic Acid from Sea-Derived Aspergillus luchuensis Hy‑6 as a Valuable Lead Compound against Plant-Parasitic Nematodes in Cucumber by Linsong Wang (6447482)

“…Root-knot nematodes pose a significant threat to crop growth and yield, thereby impacting global food security. …”

The performance of eigenvectors of the covariance matrix in a model with more complex population structure. by Joshua G. Schraiber (8027060)

<i>C</i>. <i>auris</i> uses a unique cell wall mannan layer to evade IL-1R signaling mediated host defense. by Abishek Balakumar (20189865)

Estimated marginal means (± SE) of durations of momentary frequency of highest amplitude (MFHA). by Micha Keller (11312748)

“…The most marked change can be seen during CVH intervention, with a significant increase in LF and a significant decrease in IM duration.…”

Fig 3 - by Micha Keller (11312748)

“…For MFHA durations, CVH exhibits significant concomitant ‘shifting’ of ANS activity between IM- and LF-band during CVH intervention: LF-band duration increases by the amount that IM-band decreases. …”

Discovery of Dual-Acting Biofilm Inhibitors against Pseudomonas aeruginosa by the Coupling of 3‑Hydroxypyridin-4(1<i>H</i>)‑ones with <i>N</i>‑Phenylamide QS Inhibitors by Hao-Zhong Long (19685972)

“…Mechanistic studies revealed that there was a decreased production of virulence regulated by quorum sensing system and a lack of iron acquisition under the treatment of <b>19l</b>, which led to the inhibition of biofilm. …”

List of drug resistance gene. by Shuai Huang (60512)

“…Additionally, 16S rRNA species profiling revealed that the composting process significantly altered the microbial community structure, with an increased abundance of Firmicutes and a decreased abundance of Bacteroidetes in composted pig manure. …”

Serves as the data source for Figs 1 and 2. by Shuai Huang (60512)

“…Additionally, 16S rRNA species profiling revealed that the composting process significantly altered the microbial community structure, with an increased abundance of Firmicutes and a decreased abundance of Bacteroidetes in composted pig manure. …”

Primers sequences of drug resistance genes. by Shuai Huang (60512)

“…Additionally, 16S rRNA species profiling revealed that the composting process significantly altered the microbial community structure, with an increased abundance of Firmicutes and a decreased abundance of Bacteroidetes in composted pig manure. …”