Probing the Histamine H₁ Receptor Binding Site to Explore Ligand Binding Kinetics by Sebastiaan Kuhne (1474948)

“…Analysis of structure-kinetic relationships (SKR) can contribute to an improved understanding of receptor–ligand interactions. Here, fragment <b>1</b> (4-(2-benzylphenoxy)-1-methylpiperidine) was used in different fragment growing approaches to mimic the putative binding mode of the long residence time (RT) ligands olopatadine, acrivastine, and levocetirizine at the histamine H₁ receptor (H₁R). …”

Identification of gene co-expression modules associated with MS. by Lai Jiang (2401513)

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RTA408 promotes Nrf2 expression. by Hongmei Qian (538647)

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Downregulation of TRIM37 expression exacerbates pathological damage in the MS model. by Lai Jiang (2401513)

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Overexpression <i>TRIM37</i> promotes myelin repair and inhibits cell apoptosis by upregulating PEX5. by Lai Jiang (2401513)

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Overexpression <i>TRIM37</i> enhances PEX5 protein stability by promoting PEX5 monoubiquitination. by Lai Jiang (2401513)

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Overexpression <i>TRIM37</i> inhibits inflammatory infiltration and alleviates demyelination in EAE model mice. by Lai Jiang (2401513)

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A particular class of CSR 22Gs are up-regulated in synMuv B mutants. by Ashwin Seetharaman (615458)

Mean liver weight (g) (A), liver weight/body ratio (B), hepatic triglyceride (mg/g) (C) and hepatic steatosis quantification (% area) (D) upon completion of the treatment phase. by Elsie D. Oduor (22521785)

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Punch types and its kinematics: (a) No punch (b) Long-range rear jab to head (c) Mid-range rear hook to head (d) Mid-range rear uppercut to head. by Saravanan Manoharan (21273304)

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RTA408 inhibits the mitophagy pathway. by Hongmei Qian (538647)

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Redundancy analysis of soil environmental factors and bacterial dominant communities under different water and fertilizer application patterns of greenhouse tomatoes (A, I1; B, I2;... by Xiaona Lyu (20871872)

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CTL response following combination therapy with NDV. by Hedieh Zargaran (21410233)

Fig 5 - by Lingru Ruan (18995544)

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Fig 2 - by Lingru Ruan (18995544)

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Fig 4 - by Lingru Ruan (18995544)

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Table 1_Dual variants of uncertain significance in a case of hyper-IgM syndrome: implications for diagnosis and management.docx by Nourhen Agrebi (14151222)

“…Background<p>Hyper-IgM syndrome (HIGM) is a genetic immunodeficiency characterized by elevated to normal IgM levels and decreased IgG, IgA, and IgE. The overlapping clinical presentations of different gene mutations complicate diagnosis and management.…”

RTA408 inhibits excessive autophagy in the eyes of glaucomatous mice. by Hongmei Qian (538647)

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Variation law of AE <i>b</i>-value of sandstone under different freeze-thaw cycles at a loading rate of 0.20mm/min. by Wenyu Lv (20139458)

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Variation law of AE <i>b</i>-value of sandstone under different freeze-thaw cycles at a loading rate of 0.05 mm/min. by Wenyu Lv (20139458)

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