DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

Data Sheet 1_From psychological wellbeing to distress: the role of psychological counseling interventions in university students.pdf by Francesco Craig (8214780)

“…Post-intervention, psychological distress decreased significantly (p < 0.001), with 56.7% of students falling over the clinical distress cut-off at T1 compared to 84.4% at T0. …”

Table 1_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.docx by Guojie Ji (21518650)

“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”

Scaling analyses and morphometrics of <i>Ginkgo biloba</i> seeds by Wen Gu (129075)

“…When seeds were grouped by the ellipsoid index (EI = <i>V</i>/<i>V</i>_E), the scaling exponent of <i>V</i> vs. <i>M</i> decreased from values significantly greater than one to values less than one as EI increased. …”

Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease by Halil Onder (10368032)

“…The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …”

Data_Sheet_1_Correlation between body mass index and gender-specific 28-day mortality in patients with sepsis: a retrospective cohort study.docx by Chong Li (120471)

“…</p>Results<p>The BMI and 28-day mortality exhibited an L-shaped relationship (p for nonlinearity <0.001) with significant gender-specific differences. Subgroup analysis revealed different association patterns between the male and female cohorts. …”

Table 2_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.xlsx by Siriguleng Yu (14555900)

“…</p>Results<p>The treatment significantly reduced diet-induced adiposity and decreased inflammatory responses. …”

Table 2_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx by Zhengqing Yu (12641890)

“…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…”

Image 2_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg by Yang Li (7082)

“…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …”

Image 1_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg by Yang Li (7082)

“…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …”

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”

Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv by Jie Zheng (31208)

“…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. Mechanistically, Gyg1 knockdown significantly reduced glycogen content in myeloid cells, attenuated IL-6 and TNF-α production, alleviated LPS-induced neutrophil, and modestly decreased CD40 expression in monocytes and dendritic cells. …”

Table 1_Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target.docx by Wu Di (11561998)

“…Our findings suggest that TP inhibits NF-κB and ERK signaling pathways, reduces breast cancer-induced osteoclastogenesis, and decreases NFATc1, CTSK, and RANKL expression. …”

Strategy parameters across development for male mice in set size = 2 and set size = 4 from winning computational model. by Juliana Chase (20469427)

“…RL parameter <i>α</i>₊ learning rate and decision noise parameter softmax <i>β</i> were stable across development in both set size = 2 (A-B) and set size = 4 (F-G). Both parameters S1 “Inappropriate Lose-Shift” and S3 “Inappropriate Lose-Stay” decreased significantly with age in set size = 2 (C: <i>p</i> = 0.02, E: <i>p</i> = 0.04), but not in set size = 4 (H,J). …”

Image 2_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”

Data Sheet 2_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.pdf by Meiling Liu (390553)

“…Among these, four common miRNAs (miR-342-3p, miR-576-5p, miR-15b-5p and miR-499a-5p) were significantly elevated in the infection group compared to controls in both the in-house and validation cohorts. …”

Table 1_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.xlsx by Meiling Liu (390553)

“…Among these, four common miRNAs (miR-342-3p, miR-576-5p, miR-15b-5p and miR-499a-5p) were significantly elevated in the infection group compared to controls in both the in-house and validation cohorts. …”

Data Sheet 1_Changes in sST2 and NT-proBNP levels predict early cardiac arrhythmia in breast cancer patients treated with anthracycline-containing chemotherapies.pdf by Cuncun Chen (11842427)

“…</p>Results<p>sST2 levels increased significantly from baseline to C1 (P < 0.01). NT-proBNP levels decreased from baseline to C1 and C5 (P < 0.01). …”

Table 3_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.xlsx by Meiling Liu (390553)

“…Among these, four common miRNAs (miR-342-3p, miR-576-5p, miR-15b-5p and miR-499a-5p) were significantly elevated in the infection group compared to controls in both the in-house and validation cohorts. …”

Table 4_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.xlsx by Meiling Liu (390553)

“…Among these, four common miRNAs (miR-342-3p, miR-576-5p, miR-15b-5p and miR-499a-5p) were significantly elevated in the infection group compared to controls in both the in-house and validation cohorts. …”