Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significance b » significance _ (Expand Search), significance set (Expand Search), significant _ (Expand Search)
b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significance b » significance _ (Expand Search), significance set (Expand Search), significant _ (Expand Search)
b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
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The MTT assay and the LDH assay were used to assess the effects of the hydrogel component of MBC-005 on tumor cell number and cell death.
Published 2025“…(B) There was no significant difference (NS) between LDH values for MC3 cultures at 24- and 72-hours. …”
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The spheroid assay is used to assess long-term effects of therapy on tumor cell by culturing the tumor cells in a micro-mass, which is a 3D tumor mass used as a surrogate for in vi...
Published 2025“…(B) BT474 tumor cell micro-mass cultures (purple staining) treated with 0-, 1-, 1.5-, 2-, 2.5-, and 5-mM N-allyl noroxymorphone concentrations, after 120-hours, resulted in a significant decrease of 14.7%, 23.8%, 30.6%, and 84% for the 1.5-, 2-, 2.5, and 5-mM N-allyl noroxymorphone concentrations, respectively (* = p < 0.017, *** = p < 0.0002, and **** = p < 0.0001)..…”
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Raw data set for figures in this study.
Published 2024“…Site-directed mutagenesis of the conserved catalytic histidine residue at position 370 significantly reduces its enzymatic activity. This reduction correlates with decreased HMV, affecting key virulence traits including biofilm formation and serum resistance. …”
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