Metabolite changes between pathways in <i>Salmonella</i> cells in biofilm and planktonic states. by Yuliany Guillín (20614081)

<b>Climate warming, rather than nitrogen deposition, reduces plant diversity and increases community homogenization in a desert steppe</b> by Yi Zhu (22625741)

Data Sheet 1_The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.pdf by Sijie Zhang (7429373)

“…</p>Results<p>While no association was observed between the rs724030 variant in MTNR1B and prediabetes risk in the overall cohort (P > 0.05), we found the G allele of this variant was associated with higher fasting and 30-minute plasma glucose levels, decreased Insulinogenic Index (IGI), and oral disposition index (DIo) (P = 0.009, 0.001, 0.001, and 0.007, respectively) in the normal glucose tolerance (NGT) individuals with normal BMI levels. …”

<b>Seizure-induced changes in cytokine expression and dysregulation of plasminogen activation and IGF systems following kainic acid administration in rats</b> by Elena Suleymanova (22195777)

<b>Two therapeutic approaches for vancomycin-induced acute kidney injury: urinary acidification or inhibition of organic anion transporters with probenecid</b> by Thibault Le Moulec (20854373)

<b>Morin alleviates fructose-driven disturbance of podocyte mitochondrial energy metabolism by inhibiting AMPD activity to improve glomerular injury</b> by Luyi Huang (22583081)

Supporting information Abou-Kandil et al. by Olaf Kniemeyer (8561361)

“…Deletion of <i>rtaA</i> did not significantly change the ergosterol content of <i>A. fumigatus</i>, but decreased fluorescence intensity of the sterol-binding stain filipin. …”

<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b> by Ge Qiao (21802511)

“…These analyses were further supported by experiments conducted on cell lines.</p><p dir="ltr"><b>Key findings:</b> LOXL2 has been identified as a significant prognostic biomarker in LUAD, with high expression levels correlating with poor overall survival. …”

<b>Metabolic shifts in ratio of ucOcn to cOcn towards bone resorption contribute to age-dependent bone loss in male mice</b> by Bin Wang (16631220)

<b>Differences in White Matter Microstructure in Children With Type 1 Diabetes Persist During Longitudinal Follow up: Relation to Dysglycemia</b> by Nelly Mauras (8103110)

“…</p><p dir="ltr">We observed in 182 children (121 type 1 diabetes, vs. 61 controls) who had testing at Time 4 that FA increased, and RD, AD, MD decreased significantly in both groups, with no differences between groups for FA, RD and MD over time. …”

Image 1_Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.tif by Peng Zhang (2071)

“…Additionally, in vivo experiments indicated that BBR reduced aortic lipid deposition and reduced the atherosclerotic plaque area. BBR decreased the expression levels of RAGE, p-NF-κB, TNF-α, and P62 in the aorta, and upregulated the expression levels of IL-10, CD31, VEGF, LC3B, and Beclin1. …”

Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx by Ji Yang (114503)

“…Background<p>Current therapeutic options for inflammatory bowel disease (IBD) remain suboptimal due to limited efficacy, significant side effects, and high relapse rates, necessitating novel treatment strategies. …”

Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

Table 1_Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.docx by Peng Zhang (2071)

“…Additionally, in vivo experiments indicated that BBR reduced aortic lipid deposition and reduced the atherosclerotic plaque area. BBR decreased the expression levels of RAGE, p-NF-κB, TNF-α, and P62 in the aorta, and upregulated the expression levels of IL-10, CD31, VEGF, LC3B, and Beclin1. …”

Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

<b>The Mediating Role of Mental Fatigue Awareness in the Relationship Between Perceived Stress and Psychological Well-Being Among Combat Athletes</b> by coşkun yılmaz (21505391)

“…Statistical analyses assessed the direct effects of perceived stress on psychological well-being, the effect of stress on mental fatigue awareness, and the potential mediating role of mental fatigue awareness.</p><p dir="ltr"><b>Results. </b>Perceived stress significantly increased mental fatigue awareness (b = 0.732 ± 0.064, β = 0.549, p = 0.001) and directly decreased psychological well-being (b = –0.488 ± 0.166, β = –0.191, p = 0.004). …”

Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx by Ping Zhao (47228)

“…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19⁺ B cells and CD14⁺ monocytes, but significantly decreased on CD56⁺ NK cells.We identified a distinct CD226⁺CD19⁺ B cell subset that exhibited pathogenic features in pSS. …”

Dorsal and chinmo mutually influence each other’s expression, driving tumor growth while inhibiting differentiation. by Caroline Dillard (15381444)

“…Chinmo (magenta) upregulation upon Dorsal overexpression in clones is visible in the insets bellow each image. Statistical significance was determined with an Unpaired <i>t</i> test with Welch’s correction. …”

Data Sheet 2_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx by Yang Yu (4292)

“…Among them, 12 drought-responsive candidate genes were upregulated, and TaERF13-2B was selected for further analysis. TaERF13-2B overexpression in Arabidopsis resulted in significantly reduced survival rates under drought conditions with decreased expression of stress-responsive and antioxidant enzyme genes, indicating that the TaERF13-2B gene elevated drought sensitivity in transgenic Arabidopsis. …”

Data Sheet 1_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx by Yang Yu (4292)

“…Among them, 12 drought-responsive candidate genes were upregulated, and TaERF13-2B was selected for further analysis. TaERF13-2B overexpression in Arabidopsis resulted in significantly reduced survival rates under drought conditions with decreased expression of stress-responsive and antioxidant enzyme genes, indicating that the TaERF13-2B gene elevated drought sensitivity in transgenic Arabidopsis. …”