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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significance b » significance _ (Expand Search), significance set (Expand Search), significant _ (Expand Search)
b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
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3761
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3762
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Experimental and computational analyzes revealed that (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B has the highest affinity for OSBP. Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”
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3763
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Experimental and computational analyzes revealed that (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B has the highest affinity for OSBP. Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”
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3764
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Experimental and computational analyzes revealed that (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B has the highest affinity for OSBP. Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”
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3765
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Experimental and computational analyzes revealed that (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B has the highest affinity for OSBP. Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”
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3766
RtcB cooperates with its cofactor Archease to promote axon regeneration.
Published 2025“…(D and E) Compared with <i>RtcB</i><sup><i>1-4B</i></sup> or <i>Archease</i><sup><i>PB</i></sup> heterozygotes, axon regeneration is significantly decreased in <i>RtcB</i> and <i>Archease</i> transheterozygotes. …”
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3767
Changes in intraocular pressure (IOP) from before to after omidenepag isopropyl administration in different patient groups.
Published 2025“…There was a significant decrease in IOP after starting the eye drops (<i>P</i> = 0.03, Wilcoxon signed-rank test).…”
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3768
Identification of VHL as a novel E3 ubiquitin ligase for Vpx.
Published 2025“…<p>(A, B) NanoLuc bioluminescence resonance energy transfer (NanoBRET)-based screen for the identification of Vpx-interacting E3 ligases (58 genes) in living human embryonic kidney 293 (HEK293) cells. …”
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3769
Dexmedetomidine pretreatment alleviates brain injury in middle cerebral artery occlusion (MCAO) model rats by activating PI3K/AKT/NF-κB signaling pathway
Published 2025“…DEX pretreatment reversed the effects of MCAO as evidenced by decrease in protein expression levels of TNF-α and IL-6 associated with elevated protein expression levels of PI3K/AKT/NF-κB signaling pathway. …”
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3770
Various parameters characterizing Lb related to lung volume or alveolar surface before, during and after bulk alveolarization (adulthood).
Published 2025“…During alveolarization values remain constant. At pnd 21 a significant decrease compared to 3 days old pups is visible. …”
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3771
Supplementary file 1_Global, regional, and national total burden related to hepatitis B and attributable risk factors in adults aged 65 years and older from 1990 to 2021 and projec...
Published 2025“…ASIR and ASPR both showed significant decreasing trends in males and females, with persistently higher rates observed among males across all study years. …”
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3772
Differential analysis of immune cells in brucellosis and healthy controls.
Published 2025“…<p><b>(A)</b> CIBERSORT analysis showed significantly increased CD8 + T cells and NK cells, and decreased B cells and CD4 + T cells in brucellosis. …”
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3773
Genetic insights into the interaction between chronic hepatitis B virus infection and metabolic syndrome
Published 2025“…<p>The association between chronic hepatitis B virus (HBV) infection and metabolic syndrome (MetS) remains controversial. …”
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3774
Effect of NNK on 1p-Enh activity and CYP4B1 expression.
Published 2025“…<b>(C)</b> Luciferase reporter assays showed a significant decrease in 1p-Enh activity in AC-16 and Beas-2B cells following exposure to NNK for 15 generations. …”
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3775
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3776
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3777
Deletion of glycosyltransferase <i>galE</i> impairs the InlB anchoring and pathogenicity of <i>Listeria monocytogenes</i>
Published 2024“…Taken together, <i>galE</i> deletion significantly reduced the anchoring of InlB and weakened the pathogenicity of <i>L. monocytogenes</i>. …”
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3778
Contents of PIO Program.
Published 2025“…The experimental group had lower depression than did those in the control group, but the effect is not statistically significant, so additional research is required.</p><p><b>Trial Registration:</b> CRIS (<a href="https://trialsearch.who.int/Trial2.aspx?…”
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3779
Demographic characteristics of participants.
Published 2025“…The experimental group had lower depression than did those in the control group, but the effect is not statistically significant, so additional research is required.</p><p><b>Trial Registration:</b> CRIS (<a href="https://trialsearch.who.int/Trial2.aspx?…”
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3780
Social robot PIO (version 3.5).
Published 2025“…The experimental group had lower depression than did those in the control group, but the effect is not statistically significant, so additional research is required.</p><p><b>Trial Registration:</b> CRIS (<a href="https://trialsearch.who.int/Trial2.aspx?…”