Presentation 1_Identification and validation of lactate-related gene signatures in endometriosis for clinical evaluation and immune characterization by WGCNA and machine learning.p... by Jixin Li (5801207)

“…Background<p>Endometriosis is a common benign gynecologic disease in women of reproductive age, and its manifestations remarkably decrease quality of life. Lactate, as a metabolite, exerts prominent effects across a wide range of biological processes. …”

A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets by Chao Li (145513)

“…The results revealed that piglets challenged with DLF presented clinical symptoms such as continuous high fever and an obvious decrease in daily weight gain. Importantly, the piglets immunised with SD-R exhibited notable reductions in pathological damage, especially of decreases in DLF-induced thymic atrophy. …”

Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov by Daniel Seung Kim (19510291)

“…In both our highlighted case and in our aggregate data, we report significant improvement in wall thickness, mitral regurgitation, left ventricular outflow tract obstruction and New York Heart Association symptom class. …”

Neuroprotective effects of Cannabidiol in 5XFAD Mice: Reducing amyloid and tau burden in the dorsal subiculum by Muhammad Kamal Hossain (19814445)

“…Interpretation:</b> Our results showed that CBD treatment led to a significant reduction in Aβ accumulation and a marked decrease in hyperphosphorylated tau in treated mice compared to controls. …”

Data Sheet 1_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.csv by Ling Yao (16961)

“…Among non-neoplastic digestive diseases, inflammatory bowel disease showed the most pronounced decrease. In contrast, the burden of colorectal cancer has increased annually across all age groups. …”

Table 5_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.xlsx by Ling Yao (16961)

“…Among non-neoplastic digestive diseases, inflammatory bowel disease showed the most pronounced decrease. In contrast, the burden of colorectal cancer has increased annually across all age groups. …”

Final data used in the study. by Maryam Rafiee (10368504)

“…Furthermore, an increase of one point in work ability score leads to a decrease in WMSDs in the neck, wrists/hands, low back and hips/thighs regions by 13.5%, 8%, 11.5%, and 9%, respectively.…”

Image 5_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Table 1_Association between excessive screen time and falls, with additional risk from insufficient sleep duration in children and adolescents, a large cross-sectional study in Chi... by Runquan Zhang (20393850)

“…After adjusting for relevant covariates, the associations remained significant (aOR: 1.30, 95% CI: 1.08–1.56, p = 0.006; aOR: 1.43, 95% CI: 1.10–1.87, p = 0.008).…”

Trends in spatial beta diversity over time. by Zoë J. Kitchel (21688386)

“…A lack of significant trend is shown in blue. The average linear trend across surveys (black line with 95% confidence interval in gray) is also plotted from a linear mixed effect model with a random slope and intercept for survey. …”

Table 2_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Ten and five of these upregulated genes were classified into two significantly enriched KEGG pathways: cell cycle and progesterone-mediated oocyte maturation (q-value <0.05), respectively. …”

Data Sheet 1_Pronounced impairment of B cell differentiation during bone regeneration in adult immune experienced mice.docx by Mireille Ngokingha Tchouto (20812811)

“…</p>Results<p>While the B cell proportion in young and non-immune experienced animals did not significantly change from 2 to 5 days post osteotomy in the hematoma, we found a significant decrease of the B cell proportion in the immune experienced mice, which was accompanied by the decreased expression of B cell specific genes, suggesting a specific response in immune experienced animals. …”

Table5_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Data_Sheet_1_Different responses of soil bacterial community to plant–plant interactions under organic–inorganic fertilizers affect seedling establishment during subalpine forest s... by Dandan Li (391591)

“…This finding highlights the significance of the rhizosphere bacteria on plant growth and plant community succession. …”

Image 2_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Table 1_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.docx by Ling Yao (16961)

“…Among non-neoplastic digestive diseases, inflammatory bowel disease showed the most pronounced decrease. In contrast, the burden of colorectal cancer has increased annually across all age groups. …”

Data Sheet 1_Schaftoside contributed to anti-inflammatory activity of Clinacanthus nutans extract in lipopolysaccharide-induced RAW 264.7 cells.docx by Saruda Thongyim (19372687)

“…</p>Results and Discussion<p>At a concentration of 40 μM, schaftoside significantly downregulated the expression of key inflammation-related genes, including iNOS, COX2, PGE2, PGE4, TNF-α, and IL6. …”

Table1_The long-term effect of biochar application to Vitis vinifera L. reduces fibrous and pioneer root production and increases their turnover rate in the upper soil layers.docx by Peter Beatrice (12859252)

“…Our findings demonstrate that in the long term, biochar application significantly increased soil pH, nutrient availability, and water-holding capacity causing a decrease in the production of fibrous and pioneer roots which is reflected in a reduction of the root web characterized though by a higher turnover rate. …”

The SARS-CoV-2 (COVID-19) pandemic and diagnosis and treatment of women with abnormal uterine bleeding: findings from Brazil by Ilza Monteiro (10459778)

“…</p> <p>In Brazil, during the COVID-19 pandemic, there was a decrease in AUB-related consultations, a slight increase in telehealth visits and a reduction in the use of procedures and treatments.…”

Image 1_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf by Youyi Wu (20786402)

“…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …”