Showing 19,041 - 19,060 results of 21,342 for search '(( significance p decrease ) OR ( significant decrease decrease ))', query time: 0.44s Refine Results
  1. 19041

    The animal experimental protocol. by Yuanqiang Lv (20623742)

    Published 2025
    “…Treat <i>Gallus gallus</i> exhibiting oxidative stress and immune response caused by aflatoxin b1 with optimal synbiotics for 14 days, detect the changes of inflammatory markers and oxidative stress markers of <i>Gallus gallus</i> using qRT-PCR, and identified the intestinal bacteria genera and their metabolites in the cecum of <i>Gallus gallus</i> using gut microbiota and metabolomics analysis.</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
  2. 19042

    Table 1_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx by Ik-Hwan Han (8605281)

    Published 2025
    “…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163<sup>+</sup> M2 macrophages, and increased CD8<sup>+</sup> T cell infiltration in tumor tissues. …”
  3. 19043

    Supplementary Material for: Splice variant of retinal G-protein-coupled receptor deletion (RGR-d)-mediated dysregulation of autophagy increases the susceptibility to age-related ma... by Guo Y. (2986464)

    Published 2024
    “…Beclin-1 and LC3II/I expression levels were significantly decreased and that of P62 was elevated in RGR-d cells after PA stimulation. …”
  4. 19044

    Table 2_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx by Ik-Hwan Han (8605281)

    Published 2025
    “…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163<sup>+</sup> M2 macrophages, and increased CD8<sup>+</sup> T cell infiltration in tumor tissues. …”
  5. 19045

    Supplementary file 1_Analysis of microbial composition in different dry skin areas of Beijing women.docx by Jingtao Wang (828021)

    Published 2025
    “…Hydration was significantly lower (P < 0.05) at the same skin area in the dry-skinned population compared to the healthy population. …”
  6. 19046

    Data Sheet 1_A dietary combination of red yeast rice, phytosterol ester and lycopene ameliorates hypercholesterolemia by regulating gut microbiota and activating hepatic FXR-LDLR/A... by Jingxian Xu (9374512)

    Published 2025
    “…Background<p>Excessive nutrition intake is a well-established contributor to obesity and hypercholesterolemia, both of which pose substantial risks to cardiovascular health. …”
  7. 19047

    3-D surface plot showing the interactive effect of ultrasonic frequency (kHz) and the variation ratio of DES and water on the TPC of Sabah snake grass extract. by Tong Yen Suan (21656185)

    Published 2025
    “…<p>The response surface illustrates the non-linear relationship between the two independent variables and TPC yield. …”
  8. 19048

    <b>Antiretroviral therapy </b><b>does not correct the dysregulations of plasma virome and cytokines induced by HIV-1</b> by Yingying Ma (18762652)

    Published 2024
    “…<p dir="ltr">HIV-1 infection leads to an expansion of plasma anelloviruses and dysregulation of inflammation. …”
  9. 19049

    <b>Antiretroviral therapy</b><b> does not correct the dysregulations of plasma virome and cytokines induced by HIV-1</b> by Yingying Ma (18762652)

    Published 2024
    “…<p dir="ltr">HIV-1 infection leads to an expansion of plasma anelloviruses and dysregulation of inflammation. …”
  10. 19050

    Image 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.jpg by Jiajun Chen (1279269)

    Published 2025
    “…The Prevotella melaninogenica, which belongs to the Prevotella genus, was the dominant species in the CIP/RP group and the second most abundant species in the LC-P group. Compared to the LC-P group, the CIP/RP group had significantly high levels of Prevotella melaninogenica species and lymphocyte percentage in BALF but significantly low levels of lymphocytes, eosinophils and albumin in peripheral blood. …”
  11. 19051

    Data Sheet 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.zip by Jiajun Chen (1279269)

    Published 2025
    “…The Prevotella melaninogenica, which belongs to the Prevotella genus, was the dominant species in the CIP/RP group and the second most abundant species in the LC-P group. Compared to the LC-P group, the CIP/RP group had significantly high levels of Prevotella melaninogenica species and lymphocyte percentage in BALF but significantly low levels of lymphocytes, eosinophils and albumin in peripheral blood. …”
  12. 19052

    Data Sheet 1_Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice.docx by Jessica Alves Freitas (20974076)

    Published 2025
    “…</p>Results<p>Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c and triglycerides.…”
  13. 19053

    Table1_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.docx by Chaofeng Zhang (845343)

    Published 2024
    “…The biological role of CISD2 in these drug-resistant DLBCL cell lines was subsequently assessed.</p>Results<p>Elevated CISD2 levels were found to be associated with decreased sensitivity of DLBCL patients to the R-CHOP regimen, as indicated by bioinformatics and clinical cohort analysis. …”
  14. 19054

    Data Sheet 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.docx by Lillia A. Baird (10575941)

    Published 2025
    “…At end-stage disease (i) motor neurons and neuromuscular junctions were counted, (ii) immune populations were quantified via flow cytometry in peripheral blood and spinal cord, (iii) microglial surface marker expression was quantified to assess neuroinflammation, and (iv) bulk RNA-seq was performed on spinal cord.</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”
  15. 19055

    Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

    Published 2025
    “…At end-stage disease (i) motor neurons and neuromuscular junctions were counted, (ii) immune populations were quantified via flow cytometry in peripheral blood and spinal cord, (iii) microglial surface marker expression was quantified to assess neuroinflammation, and (iv) bulk RNA-seq was performed on spinal cord.</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”
  16. 19056

    Image1_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.JPEG by Chaofeng Zhang (845343)

    Published 2024
    “…The biological role of CISD2 in these drug-resistant DLBCL cell lines was subsequently assessed.</p>Results<p>Elevated CISD2 levels were found to be associated with decreased sensitivity of DLBCL patients to the R-CHOP regimen, as indicated by bioinformatics and clinical cohort analysis. …”
  17. 19057

    Image2_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.JPEG by Chaofeng Zhang (845343)

    Published 2024
    “…The biological role of CISD2 in these drug-resistant DLBCL cell lines was subsequently assessed.</p>Results<p>Elevated CISD2 levels were found to be associated with decreased sensitivity of DLBCL patients to the R-CHOP regimen, as indicated by bioinformatics and clinical cohort analysis. …”
  18. 19058

    Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

    Published 2025
    “…At end-stage disease (i) motor neurons and neuromuscular junctions were counted, (ii) immune populations were quantified via flow cytometry in peripheral blood and spinal cord, (iii) microglial surface marker expression was quantified to assess neuroinflammation, and (iv) bulk RNA-seq was performed on spinal cord.</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”
  19. 19059

    Supplementary Material for: The impact of left ventricular structure and function on mortality in patients with aortic valve infective endocarditis treated with aortic valve replac... by figshare admin karger (2628495)

    Published 2025
    “…The mean LVEF was 54±11% preoperatively, decreasing to 51±11% postoperatively. The mean baseline LVEDd was 5.8±0.9 cm in males and 5.0±0.9 cm in females (p<0.001), decreasing to 5.2±0.9 cm in males and 4.7±0.6 cm in females after surgery (p=0.006). …”
  20. 19060

    Supplementary data.xlsx by Danjun Li (21443051)

    Published 2025
    “…<p dir="ltr">Telomere length(TL) is important for the maintaining the individual health of a species. …”