Image 1_TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury.pdf حسب Ting Zhou (38572)

"…To explore the molecular mechanisms of TSLP’s effect, analysis of transcriptome sequencing and single-cell transcriptome sequencing and subsequent experiments were performed.</p>Results<p>In LPS-induced acute lung injury models, pretreatment with TSLP significantly alleviated lung injury, suppressed inflammatory cytokines secretion, and reduced macrophages and neutrophils infiltration. …"

Table 1_Exhaled breath particles as a diagnostic tool for bronchiolitis obliterans syndrome in lung transplant recipients: a longitudinal study.docx حسب Runchuan Gu (10911582)

"…Background<p>Long-term survival after lung transplantation is significantly shorter compared with other solid organ transplantations. …"

Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

DataSheet_1_RETRACTED: Tregs depletion aggravates activation of astrocytes by modulating IL-10/GXP4 following cerebral infarction.docx حسب Shuai Wang (109515)

"…Subsequently, we assessed renal fibrosis, renal ferroptosis, Treg infiltration, astrocyte activation, as well as the expression levels of active GPX4, FSP1, IL-10, IL-6, and IL-2 after a 2-week period.</p>Results<p>In the tMCAO mouse model, depletion of tregs protected against activation of astrocyte and significantly decreased FSP1, IL-6, IL-2, and NLRP3 expression levels, while partially reversing the changes in Tregs. …"

Table 8_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx حسب M. Elakkya (21760439)

"…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.</p>Discussion<p>Our results show that the A. chroococcum W5 strain has great potential for the development of novel formulations. …"

Table 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.xlsx حسب Xiao-Ting Luo (20836646)

"…Next, CTSS was confirmed to be lower expressed in peripheral monocytes of septic patients. Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. …"

Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes حسب Motoshi Kozakai (22435636)

"…MicroRNA and protein profiles of MSC-exs were examined.</p> <p>MSC-exs significantly attenuated AA progression (2.04 ± 0.20 mm in the saline group and 1.34 ± 0.13 mm in the MSC-ex group, P = 0.004). …"

DataSheet1_Type I-conventional dendritic cells support the progression of multiple myeloma in the bone marrow.docx حسب Sayaka Suzuki (248729)

"…Consequently, the frequencies of exhausted CD8 T cells and regulatory T cells significantly decreased in the bone marrow of cDC1-depleted mice.…"

Image 2_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg حسب Xiao-Ting Luo (20836646)

"…Next, CTSS was confirmed to be lower expressed in peripheral monocytes of septic patients. Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. …"

Table 4_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx حسب M. Elakkya (21760439)

"…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.</p>Discussion<p>Our results show that the A. chroococcum W5 strain has great potential for the development of novel formulations. …"

Image 4_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif حسب M. Elakkya (21760439)

"…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.</p>Discussion<p>Our results show that the A. chroococcum W5 strain has great potential for the development of novel formulations. …"

Supplementary file 2_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx حسب Guixin He (2547469)

"…Background<p>Cancer‐related fatigue (CRF) is a prevalent and multifactorial symptom that significantly impairs the quality of life in cancer patients. …"

Table 3_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx حسب M. Elakkya (21760439)

"…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.</p>Discussion<p>Our results show that the A. chroococcum W5 strain has great potential for the development of novel formulations. …"

Image 3_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif حسب M. Elakkya (21760439)

"…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.</p>Discussion<p>Our results show that the A. chroococcum W5 strain has great potential for the development of novel formulations. …"

Supplementary file 1_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx حسب Guixin He (2547469)

"…Background<p>Cancer‐related fatigue (CRF) is a prevalent and multifactorial symptom that significantly impairs the quality of life in cancer patients. …"

Table 6_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx حسب M. Elakkya (21760439)

"…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.</p>Discussion<p>Our results show that the A. chroococcum W5 strain has great potential for the development of novel formulations. …"

Table 2_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx حسب M. Elakkya (21760439)

"…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.</p>Discussion<p>Our results show that the A. chroococcum W5 strain has great potential for the development of novel formulations. …"

Table 1_Case Report: Identification of a novel hemizygous CFAP47 variant in a primary ciliary dyskinesia patient with dual ciliary and flagellar defects.docx حسب Miao He (148269)

"…Experimental validation revealed significantly decreased CFAP47 mRNA levels in the patient’s sperm and the HEK293 cells transfected with mutant plasmid compared to controls, suggesting impaired transcript stability.…"

Image 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg حسب Xiao-Ting Luo (20836646)

"…Next, CTSS was confirmed to be lower expressed in peripheral monocytes of septic patients. Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. …"