CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells. by Jovana Deretic (13113617)

“…Ciliary vesicle ectocytosis or fragments were categorized based on the size of the released EVs, vesicle < 500 nm and fragment > 500 nm, and plotted as a bar plot. (<i>p</i> values of Welch’s <i>t</i> test, **<i>p</i> = 0.0074, ***<i>p</i> = 0.0007, ns = not significant). …”

Association of COL4A2 indel polymorphism with the development of stomach adenocarcinoma in Chinese populations by Huihai Shi (19754499)

“…Logistic regression analysis revealed that both the heterozygote and homozygote 4-bp del/del genotypes were significantly associated with a decreased risk of STAD, even after controlling for other variables (adjusted odds ratio [OR] = 0.663, 95% confidence interval [CI] 0.519–0.848, <i>p</i> = 0.037; OR = 0.422, 95% CI 0.290–0.614, <i>p</i> = 0.000005, respectively). …”

Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro... by Liang Wu (131111)

“…Untargeted metabolomics was conducted to identify serum metabolic variations and elucidate enriched metabolic pathways associated with HSYA treatment.</p>Results<p>HSYA significantly inhibited HFD-induced weight gain and alleviated liver inflammation. …”

DataSheet1_Efficacy and safety of danshen class injections in the treatment of coronary heart disease: a network meta-analysis.docx by Shuang Dai (1413496)

“…</p>Conclusion<p>The combined treatment of DSCIs and WM more significant efficacy in patients with CHD compared to WM treatment alone, including clinical efficacy evaluation, inflammatory markers, and oxidative stress markers. …”

Data_Sheet_1_Prognostic value of the Naples Prognostic Score in adult chronic obstructive pulmonary disease: NHANES 2005–2018.PDF by Yue Kang (427523)

“…All-cause mortality [HR (95%CI), 1.68 (1.39–2.85)] and hypertension-related mortality [HR (95%CI), 67.64 (8.88–515.07)] of group 2 were significantly elevated.</p>Conclusion<p>The findings of this study suggested that the NPS serves as a robust prognostic indicator of COPD.…”

Image_1_Prognostic value of the Naples Prognostic Score in adult chronic obstructive pulmonary disease: NHANES 2005–2018.TIFF by Yue Kang (427523)

“…All-cause mortality [HR (95%CI), 1.68 (1.39–2.85)] and hypertension-related mortality [HR (95%CI), 67.64 (8.88–515.07)] of group 2 were significantly elevated.</p>Conclusion<p>The findings of this study suggested that the NPS serves as a robust prognostic indicator of COPD.…”

Table 1_The mitochondrial function of peripheral blood cells in cognitive frailty patients.docx by Li Qin (205731)

“…The Sensitive analysis showed that the area under curve values for mtDNAcn and ROS were 0.653 and 0.925.</p>Conclusion<p>Age, lower educational attainment, malnutrition, and depression are significant risk factors for CF. …”

Image_2_Prognostic value of the Naples Prognostic Score in adult chronic obstructive pulmonary disease: NHANES 2005–2018.TIFF by Yue Kang (427523)

“…All-cause mortality [HR (95%CI), 1.68 (1.39–2.85)] and hypertension-related mortality [HR (95%CI), 67.64 (8.88–515.07)] of group 2 were significantly elevated.</p>Conclusion<p>The findings of this study suggested that the NPS serves as a robust prognostic indicator of COPD.…”

Table_1_Effectiveness of sofosbuvir-based treatments for patients with hepatitis C virus genotype 6 infection: a real-world study from East China.DOC by Fan-Rong Jiang (20325720)

“…Background<p>Over the past decade, the proportion of hepatitis C virus (HCV) genotypes (GT) 1 and 2 has decreased in almost all regions of China, while GT 3 and 6 have emerged as new challenges. …”

Image 1_Association of estimated glucose disposal rate with chronic kidney disease: comparative analysis against traditional insulin resistance indices.jpeg by Yuanxin Liu (6307949)

“…Background<p>Chronic kidney disease (CKD) is a widespread condition, marked by significant morbidity and mortality rates, particularly in individuals with comorbidities such as diabetes and hypertension. …”

Table 1_The relationship between dietary sodium intake and all-cause mortality in patients with non-alcoholic fatty liver disease: a cohort study from NHANES 2003–2018.docx by Jiajun Li (1410187)

“…</p>Conclusion<p>This study suggests that higher sodium intake in individuals with NAFLD is associated with increased disease incidence but decreased all-cause mortality. …”

Data Sheet 1_Association of estimated glucose disposal rate with atrial fibrillation, heart failure and cardiovascular mortality in patients with diabetes: a prospective cohort stu... by Zhen Tan (384977)

“…The cumulative incidence of AF, HF, and cardiovascular mortality in the higher quartiles of GDR were significantly lower than those in the lowest quartile (log-rank P < 0.001 for all). eGDR exhibited an independent negative linear correlation with the risk of AF (HR = 0.94, 95% CI: 0.91-0.96), HF (HR = 0.78, 95% CI: 0.74-0.82), and cardiovascular mortality (HR = 0.86, 95% CI: 0.83-0.88) risk. eGDR made the most significant contribution to the predicted outcomes. …”

Table 1_Effectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China.do... by Hongxiang Ji (11235519)

“…The incidences of AEs were similar between the HI group and control group with all p-value >0.05.</p>Conclusion<p>The HI therapy is related to significant amelioration in BP levels with acceptable safety profile in Chinese hypertensive adults after 24 weeks of treatment, building a clinical ground for further research to evaluate the antihypertensive effect of HI therapy.…”

Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat... by Yuhua Jiang (10300159)

“…Moreover, the incidence of adverse events (AEs) was similar to that observed in the control group, which included both placebo and potent statin groups, with no significant differences identified in our study (P > 0.05).…”

Table 1_Analysis of growth variations and expression patterns of auxin response factor gene family in Fallopia multiflora under different light qualities.xlsx by Wenze Liu (22817513)

“…Results showed that the blue-light treatment group significantly increased the leaf area by 46.19% and chlorophyll content by 7.35%, decreased the plant height by 20.92%, and increased the THSG content in roots by 28.37% and in stems by 27.15%. …”

Data Sheet 1_Administration of anticoagulation strategies for portal vein thrombosis in cirrhosis: network meta-analysis.docx by Hui-Jun Li (1480486)

“…Warfarin and TIPS were recommended for reducing the frequency of bleeding events, while LMWH plus warfarin and DOACs proved to be most effective in decreasing the rate of major bleeding events. Warfarin, heparin plus DOACs plus warfarin, and DOACs demonstrated the most significant reduction in mortality rates, highlighting its potential as an effective intervention. …”

Table_1_Psychological wellbeing among carers of children and adolescents with physical disabilities in North-Eastern Tanzania—a cross-sectional survey study.docx by Elia Asanterabi Swai (15337336)

“…Introduction<p>Caring for physically disabled children, particularly in contexts where resources are often insufficient or absent, exposes primary carers to significant psychological strain. …”

Table 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.doc by Chanchan Xiao (9522614)

“…However, significant knowledge gaps remain regarding the CD8 T-cell immune reactivity to the Omicron variant. …”

Image 1_Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021.tiff by Keyi Yu (8958845)

“…Furthermore, age-period-cohort (APC) analyses assessed the effects of age, time, and birth cohort, while an extended autoregressive integrated moving average model (ARIMA model) was used to forecast the psoriasis burden in China from 2022 to 2036.</p>Results<p>Between 1990 and 2021, China experienced significant changes in its age-standardized incidence rate (ASIR), age-standardized prevalence rate (ASPR), and age-standardized DALY Rate (ASDR). …”

Image 1_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif by Wei Liu (20030)

“…Active components of KSG and their potential targets and pathways were identified using mass spectrometry and network pharmacology, while partial validation was performed using molecular docking and Western blotting.</p>Results<p>In vivo, KSG significantly alleviated scopolamine-induced cognitive deficits in mice. …”