Docetaxel and quercetin-loaded lipid nanocarrier optimized by quality by design for glioblastoma therapy: a ligand-conjugated and therapeutic repurposing approach حسب Zufika Qamar (22259678)

"…Compared to non-conjugated NLC and (DTX-QUR) suspension (SUS), Tf-(DTX-QUR) NLC showed 3.6- and 5.8-fold decrease in IC₅₀, respectively. Cellular uptake studies demonstrated significantly (<i>***p < 0.001</i>) high internalization of Tf-conjugated NLC to U87-MG cells. …"

Data Sheet 1_Incidence of hyperkalemia RAASi and SGLT-2i treatment in individuals with diabetic kidney disease: a systematic review and network meta-analysis.docx حسب Yahui Yuan (12112503)

"…SGLT-2i (SUCRA = 88.5%) was found to significantly reduce the risk of hyperkalemia. In contrast, the combination of ACEI/ARB + MRA (SUCRA = 5.7%) increased the risk of hyperkalemia. …"

Prior immunological memory to pertussis toxin affects the avidity development of anti-PT IgG antibodies after acellular pertussis booster vaccination حسب Aapo Knuutila (12239402)

"…The development of avidity from one month after vaccination to a year after was highly individual, with some participants having either a decrease, an increase or a stagnant level of avidity. …"

Image 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif حسب Chen Chen (6544)

"…Transcriptomic analysis revealed that AT-1 significantly modulated the expression of S100A8 and S100A9. …"

Data Sheet 1_Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity.docx حسب Krishma Tailor (13730582)

"…Furthermore, we found that subcutaneous CV1574-1 showed significantly reduced hypoglycemic effect compared to injection of IGF-1 itself. …"

<b>Insight into the effects of citric acid on the transformation of chemical</b><b> speciation</b><b> of Cd in</b> <b>biochar amended contaminated soil:</b> <b>Implications for bio... حسب Renhui Miao (18618601)

"…<p dir="ltr">Understanding the roles of low-molecular-weight organic acids (LMWOAs) in the transformation of chemical speciation of heavy metals in contaminated soil amended by biochar is of great significance for assessing the effectiveness of this carbonaceous amendment. …"

Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... حسب Haotian Li (640676)

"…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…"

Mix details of samples (kg/m³). حسب Fadi Althoey (13040091)

"…Durability was enhanced with a 14–17% reduction in water absorption and sorptivity and a 25.2% decrease in chloride penetration. Acid resistance improved by 26%. …"

ASVs abundances across microbiota samples. حسب Melany Cervantes-Echeverría (22794116)

"…Despite persistent dietary stress, FVT significantly improved glucose tolerance. Longitudinal profiling by virome shotgun metagenomics and bacterial 16S rRNA sequencing revealed marked, durable shifts in both viral and bacterial community composition. …"

Table 2_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.docx حسب Ruixian Liu (5743817)

"…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …"

Image 1_Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats.pdf حسب Silvia Granata (2678077)

"…Furthermore, inactivation of key androgenic enzymes, such as 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, together with decreased testosterone synthesis suggest a potential impairment of male gonadal function.…"

Table 4_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx حسب Ziqi Han (12840074)

"…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …"

Image 2_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf حسب Ruixian Liu (5743817)

"…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …"

Table 2_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... حسب Rongrong Lu (322302)

"…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …"

F-TransR experimental effect diagram. حسب Guibing You (21728593)

"…On the Reddit dataset, MSE and MAPE decrease by 6.6% and 5.3%, respectively, and improves to 0.854. …"

Table 1_Cardiopulmonary exercise response at high altitude in patients with congenital heart disease: a systematic review and meta-analysis.pdf حسب Marco Vecchiato (4591219)

"…Nevertheless, the patients with CHD showed a smaller decrease in peak workload [10.61 W (95% CI: 2.33–18.88)] and peak saturation [1.22% (95% CI: 0.14–2.30)] between LA and HA compared to the controls. …"

DataSheet1_A lightweight MHDI-DETR model for detecting grape leaf diseases.pdf حسب Zilong Fu (20392494)

"…The original residual backbone network was improved using the MobileNetv4 network, significantly reducing the model’s computational requirements and complexity. …"

Image 4_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf حسب Ruixian Liu (5743817)

"…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …"

Table 1_Manure substitution for chemical nitrogen enhances soil quality without compromising maize yield: a short-term field experiment in Northeast China.xlsx حسب Chao Zhou (471522)

"…</p>Results and disscussion<p>Compared to CK, only 25% substitution rate maintained maize yield, while 50‒100% manure substitution decreased maize yield by 15.9‒67.2%. This is primarily due to the decrease in root biomass (13.5‒29.1%), length (14.8‒43.3%), surface area (14.1‒48.8%) and volume (17.9‒53.4%). …"

Table 2_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.xlsx حسب Giulia Santarelli (14246638)

"…We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …"