Presentation 3_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... by Gyeong Ho Baek (21382907)

“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”

Data Sheet 1_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi... by Gyeong Ho Baek (21382907)

“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”

Comparison of the trend of people’s perceptions and the climatic trends (social data: Quantitative data: Household survey (n = 660); qualitative data: Focus group discussions (n =... by Parbati Phuyal (8687400)

“…Depending on the perception, the presence of a trend (yes, no, unclear/mixed) or a trend direction (increase, decrease, unclear) is given. Significance of each data type is presented in detail in Figs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317786#pone.0317786.g002" target="_blank">2</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317786#pone.0317786.g005" target="_blank">5</a>. …”

<i>MMP-1</i> OE restores <i>5HT</i>_<i>2A</i><i>R</i>-deficient experience-dependent pruning. by Vanessa Kay Miller (19775496)

“…<i>MMP-1</i> OE restores synaptic pruning with a significant decrease of innervation volume in response to the EB odorant experience (blue, <i>n</i> = 10/condition, <i>p</i>-value = 4.43 × 10⁻¹³), which is nearly identical to the control. …”

Data Sheet 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi... by Gyeong Ho Baek (21382907)

“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”

Presentation 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... by Gyeong Ho Baek (21382907)

“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”

Example of a choice set for Best Worst Scaling. by Yachiyo Tobita (20613887)

“…<div><p>The COVID-19 pandemic triggered social and economic stagnation worldwide, significantly impacting people’s lives. In addition, the Russia-Ukraine war that began in 2022 resulted in rising food prices globally, severely affecting low- and middle-income countries. …”

Data Sheet 1_Utility of nonlinear analysis of heart rate variability in early detection of metabolic syndrome.docx by José Alberto Zamora-Justo (21590657)

“…Introduction<p>Metabolic syndrome (MetS) is a clinical condition characterized by multiple risk factors that significantly increase the likelihood of developing cardiovascular diseases and type 2 diabetes. …”

Data Sheet 1_The response of soil microbial community to application of organic amendment to saline land.pdf by Peifei Cong (510747)

“…In addition, after the application of microbial organic fertilizer, RB41, blastococcus and solirubrobacter significantly increased, while Melothermus and Herpetosiphon significantly decreased.…”

<b>Cascade reservoir development exerts greenhouse gas emissions through nutrient retention and modification of hydrological regimes</b> by Li Chunhui (19796262)

“…The results show that the concentrations of CO2and CH4in the reservoir area are generally higher than those in the natural river area and decrease gradually along the flow direction. The CO2flux increased along the flow direction, whereasthe CH4flux decreased, indicatingobvious spatial heterogeneity. …”

Image 1_Clinical outcomes of an intelligent pressure-controlled disposable ureteroscope for Laser lithotripsy in renal stone surgery: a retrospective matched cohort study.tif by Zhong Lv (4568410)

“…The overall complication rate was significantly lower in the experimental group</p>Conclusions<p>The use of an intelligent pressure-controlled disposable ureteroscope with laser lithotripsy for upper urinary tract surgeries can effectively reduce postoperative inflammation indicators, decrease average hospital stay and renal pelvis pressure, and improve the initial and total stone clearance rates.…”

Table 1_Unraveling the physiological and ultrastructural responses of wheat to combat cobalt stress and the protective role of Jania rubens related to antioxidant defense and cellu... by Gehad A. Ragab (18267912)

“…Wheat seedlings were subjected to cobalt chloride (150 mM) irrigation, which was previously primed with either water or J. rubens extract. Co stress significantly impaired growth by reducing water content and essential nutrients (K, Mg, and Fe), leading to a 42.42 and 23.8% decrease, respectively, in root and shoot biomasses, a 9% reduction in photosynthetic efficiency, visible chlorosis, and root thickening. …”

<b>The role of the </b><b>LncRNA </b><b>XIST/miR-15a-5p/ MN1</b><b>signaling </b><b>axis in gender disparities in bladder cancer prognosis</b> by Qingshui Wang (17151220)

“…Increased XIST mRNA levels were significantly associated with dismal overall survival in female BC patients. …”

Table 1_The association between a dietary index for the gut microbiota and frailty in older adults: emphasising the mediating role of inflammatory indicators.docx by Huangyi Yin (18593848)

“…After adjusting for all of the covariates, each unit increase in the DI-GM was associated with a 6% decrease in the prevalence of frailty (OR = 0.94; 95% CI: 0.89, 0.99; p = 0.020). …”

Image 2_Clinical outcomes of an intelligent pressure-controlled disposable ureteroscope for Laser lithotripsy in renal stone surgery: a retrospective matched cohort study.tif by Zhong Lv (4568410)

“…The overall complication rate was significantly lower in the experimental group</p>Conclusions<p>The use of an intelligent pressure-controlled disposable ureteroscope with laser lithotripsy for upper urinary tract surgeries can effectively reduce postoperative inflammation indicators, decrease average hospital stay and renal pelvis pressure, and improve the initial and total stone clearance rates.…”

Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma by Marianna Carrabotta (8193039)

“…<b>A,</b> Inhibition of PDX-CDS #4-C tumor growth after treatments with trabectedin and/or NVP-BEZ235. Significant reduction in tumor growth was observed after single treatments (*, <i>P</i> < 0.05, Student <i>t</i> test) but the inhibition increased after combination of the two drugs (significance was at least ***, <i>P</i> < 0.001, Student <i>t</i> test starting from day 23) or to single treatments (*, <i>P</i> < 0.05). …”

Table 2_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table 6_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table 3_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Image 1_Elevated thiamine level is associated with activating interaction between HIF-1α and SLC19A3 in experimental myopic guinea pigs.jpeg by Zhongyu Ma (12275357)

“…</p>Results<p>Compared with the normal control (NC) group, the LIM group guinea pigs showed a significant increase in axial length and decrease in refractive error, as well as a thinning of choroidal thickness and loosening of tissue structure. …”