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significance testing » significance set (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significance testing » significance set (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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18241
Table 2_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx
Published 2025“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”
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18242
SNAP-25 (1-197) binds to syntaxin-1A, and the interaction is enhanced by Ser187 phosphorylation.
Published 2025“…<b>(C and D)</b> PMA treatment further decreases neurotransmitter release when a low level of SNAP-25 cleavage is present. …”
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18243
Data Sheet 1_The efficacy and safety of panax quinquefolius saponin for heart failure: a systematic review and meta-analysis.pdf
Published 2025“…The results of a meta-analysis under a random-effects model showed that adjuvant PQS therapy significantly increased LVEF (MD = 6.23, 95% CI [4.35, 8.12], P < 0.00001), 6MWTD (MD = 25.26, 95% CI [8.23, 42.30], P = 0.004), and decreased BNP/NT-pro-BNP (MD = −187.94, 95% CI [−267.20, −108.67], P < 0.00001), LVEDV (MD = −22.83, 95% CI [−42.79, −2.87], P = 0.02), LVEDD (MD = −4.76, 95% CI [−5.77, −3.74], P < 0.00001), and LVESV (MD = −11.86, 95% CI [−19.89, −3.83], P = 0.004) in patients with HF.…”
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18244
Table 4_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18245
Broader frequency tuning in auditory cortex of <i>Fmr1</i> KO rats despite unaltered subcortical tuning properties.
Published 2025“…**<i>p</i> < 0.01, ***<i>p</i> < 0.0001, ns = not significant. Data and code underlying this figure can be found at <a href="http://doi.org/10.5281/zenodo.15559344" target="_blank">http://doi.org/10.5281/zenodo.15559344</a>. …”
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18246
Table 3_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18247
Principal component analysis of soil parameters.
Published 2025“…The result showed that slope gradients, soil depths, and slope gradients interacting with soil depths had very highly, highly and significant effects on selected soil parameters, exchangeable bases, and extractable micronutrients. …”
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18248
Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg
Published 2025“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”
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18249
Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc...
Published 2025“…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…”
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18250
Datafiles and R script for analyses and figures for submitted manuscript titled: Loss of dominant tree-mycorrhizal mutualism increases soil fungal diversity and alters community st...
Published 2025“…Fungal alpha diversity was significantly greater in the OG<sub>100</sub> and OG<sub>50</sub> compared to the control, largely driven by decreased ECM abundance and increased saprophytic fungal abundance in OG<sub>100</sub> and OG<sub>50</sub>. …”
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18251
Table 6_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18252
Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx
Published 2025“…The use of intravenous thrombolysis decreased (52.4% to 40.4%; p<sub>trend</sub><0.01). …”
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18253
Table 2_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18254
Fig. 2 Suppression of miRNA-21-5p ameliorates ovarian pathological alterations, hormonal imbalance, and insulin resistance in PCOS-IR rats.
Published 2025“…(B) Silencing miRNA-21-5p significantly lowered serum luteinizing hormone (LH) levels in PCOS rats. …”
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18255
A Locally Linear Dynamic Strategy for Manifold Learning.
Published 2025“…In contrast to alignment modulation, the change in the spectrum is largely non-selective. exhibits no significant change for both signal-oriented (blue) and noise-oriented (orange) modes. …”
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18256
Spearman Correlation Coefficient results under feature perturbation.
Published 2025“…Each epigenetic signal was perturbed separately when the model was trained with GSC1 and tested with GSC2. The model performance when H3K27Ac signals were perturbed was significantly decreased in comparison to the other signals.…”
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18257
Data Sheet 1_Qifuyin alleviates anxiety and depression in 3×Tg-AD mice by modulating neuroendocrine function.zip
Published 2025“…In the QFY-treated group, plasma CORT levels were significantly decreased, whereas FSH and LH levels were significantly increased. …”
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18258
Effects of cell-type specific h- and m-adaptation gains on SLE rates.
Published 2025“…With few exceptions, changes in and exhibit a significantly different SLE rate from the default values (two-sample t-test, <i>p</i> < 0.05). …”
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18259
Table 1_Complex evaluation of coagulation, fibrinolysis, and inflammatory cytokines in SARS-CoV-2 infected pregnant women: a prospective, case-control study.docx
Published 2025“…Admission IL-1β, and IL-33 were significantly lower, while IL-18 was significantly higher in cases when COVID-19 became more severe, along with significantly decreased FVIII, FXIII and plasminogen. …”
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18260
<b>Distributed Hydraulic Micro-Cooling (MHD): A Low-Cost, High-Impact Urban Heat Mitigation Strategy</b> / <b>Enfriamiento Hidráulico Micro-Distribuido (MHD): Estrategia Urbana de...
Published 2025“…Large thermal masses such as roofs, asphalt roads, and concrete structures store significant amounts of solar radiation during the day (up to 1200–1600 MJ/m²). …”