Data Sheet 1_Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.docx by Tianyao Li (7388201)

“…It also decreased Aβ deposition and ameliorated neuronal apoptosis in the cerebral cortex. …”

Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif by Jyotsna Mishra (3703195)

“…When both mitochondrial fractions were exposed to increasing mCa²⁺ loads we observed decreased mCa²⁺ sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca²⁺ (ss[Ca²⁺]_e) compared to non-synaptic mitochondria. …”

Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi... by Yiran Wang (1492303)

“…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I² = 23%) in patients with SGLT-2i treatment compared with non-users. …”

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif by Jyotsna Mishra (3703195)

“…When both mitochondrial fractions were exposed to increasing mCa²⁺ loads we observed decreased mCa²⁺ sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca²⁺ (ss[Ca²⁺]_e) compared to non-synaptic mitochondria. …”

Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor... by Ying Feng (151159)

“…The overall disease burden decreased with age, particularly when high BMI exposure was below the 40th percentile (P40). …”

Baumer-TPW_2023_Dopamine-Monocytes_PMID37251548.xlsx by Tiffany Powell-Wiley (18098425)

“…Furthermore, Filamin A (FLNA), a</p><p dir="ltr">prominent actin-crosslinking protein, that is known to regulate CCR2 recycling, significantly decreased in DA-</p><p dir="ltr">treated NCM (p < 0.05), indicating a reduction of CCR2 recycling. …”

Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif by Jyotsna Mishra (3703195)

“…When both mitochondrial fractions were exposed to increasing mCa²⁺ loads we observed decreased mCa²⁺ sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca²⁺ (ss[Ca²⁺]_e) compared to non-synaptic mitochondria. …”

Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX by Ji Zeng (4336561)

“…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…”

Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b... by Ying Feng (151159)

“…The overall disease burden decreased with age, particularly when high BMI exposure was below the 40th percentile (P40). …”

Supporting data for "DECODING THE NEUROIMMUNE AXIS OF HEAD AND NECK CANCER TO ENHANCE IMMUNOTHERAPEUTIC OUTCOMES" by Ravi Kishan (11263155)

“…Genetic ablation of PTHLH resulted in dysregulation of neurotrophic signaling pathways essential for intra-tumoral innervation, significant reduction in tumor burden, and enhanced antitumor immunity —evidenced by increased CD8+ and CD4+ T cell infiltration, as well as decreased immunosuppressive markers. …”

Effects of exogenous phytohormone 5-ALA on fruit quality and volatile metabolites of ' Meizao ' sweet cherry by Haichao Guo (22550126)

“…At the same time, the anthocyanin content decreased significantly by 64.47% compared with the control, whereas the contents of flavonoids, total phenols, and tannins increased by 114.62%, 7.80%, and 1.67%, respectively. …”

Image 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.jpeg by Hana Kahleova (618836)

“…Three-day dietary records were analyzed, and Potential Renal Acid Load (PRAL) and Net Endogenous Acid Production (NEAP) were calculated as markers of dietary acid load, and their relationship was tested with changes in body weight.</p>Results<p>Compared with no change on the Mediterranean diet, PRAL and NEAP significantly decreased on the vegan diet; effect sizes: −25.8 (95% CI −34.1 to −17.5); p < 0.001; and −27.1 (95% CI −35.4 to −18.7); p < 0.001, respectively. …”

Table 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.docx by Hana Kahleova (618836)

“…Three-day dietary records were analyzed, and Potential Renal Acid Load (PRAL) and Net Endogenous Acid Production (NEAP) were calculated as markers of dietary acid load, and their relationship was tested with changes in body weight.</p>Results<p>Compared with no change on the Mediterranean diet, PRAL and NEAP significantly decreased on the vegan diet; effect sizes: −25.8 (95% CI −34.1 to −17.5); p < 0.001; and −27.1 (95% CI −35.4 to −18.7); p < 0.001, respectively. …”

Table 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.xlsx by Huijing Tang (19133347)

“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”

Supplementary file 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.docx by Huijing Tang (19133347)

“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”

Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC by Xikai Luo (21520875)

“…Rs2071029T promoter activity was significantly higher than that of rs2071029C promoter (<i>p</i> = 0.014). …”

Data Sheet 1_The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma.docx by Yu-Fei Wang (322119)

“…</p>Results<p>The invasion and migration capacities of nasopharyngeal carcinoma cells decreased significantly after CENPN knockdown, whereas the overexpression of CENPN significantly promoted the invasion and metastasis abilities of nasopharyngeal carcinoma cells. …”

Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”