First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

Fig 3 - by Laura Garcia-Toscano (20477540)

“…</b> Mutant <i>hsp-90</i> significantly decreases the levels of total and phosphorylated species of TDP-43 (pTDP-43). …”

Table 1_Relationship between nocturia, depression, and cognitive function and the mediating effects of nutritional indexes in older adults: data from NHANES 2011–2014.docx by Yin Xu (159474)

“…Thus, improving nutrition may decrease the risk of nocturia in older adults.</p>…”

Table 1_Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide.docx by Junyong Wang (3807964)

“…The half-life of YTP in plasma is significantly longer than that of YW12D and TP5. YTP also displays an improved ability to protect the host from CTX-induced weight loss and thymus and spleen indices decrease than YW12D and TP5. …”

Urbanization and climate jointly shape the composition of plant life forms by Zhiwen Gao (19941582)

“…The compositions of plant life forms were significantly controlled by urbanization intensity and annual mean temperature. …”

Table 1_The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.docx by Liuzhen Yang (20449762)

“…The results showed a significant decrease in fasting blood glucose levels (SMD = −0.79, 95% CI: −1.11 to −0.46). …”

Supplementary file 1_Antibiotic pretreatment inhibits white band disease infection by suppressing the bacterial pathobiome.docx by Jason D. Selwyn (2633932)

“…We found the prophylactic use of antibiotics led to significantly reduced infection rates in disease exposed corals with a 30-percentage point decrease in the infection rate. …”

Image 2_The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae.pdf by Bar Piscon (20906495)

“…These phenotypes are associated with repression of flagellin (fliC) transcription and a sharp decrease in the occurrence of conjugative pili in the presence of glycocholic acid, respectively.…”

Table 1_The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae.docx by Bar Piscon (20906495)

“…These phenotypes are associated with repression of flagellin (fliC) transcription and a sharp decrease in the occurrence of conjugative pili in the presence of glycocholic acid, respectively.…”

Data Sheet 1_Effects of screw-pressing temperature on the functional properties and structural characteristics of apricot (Prunus armeniaca L.) kernel protein isolates.docx by Li Zhang (8200)

“…The decrease in fluorescence intensity and the fluorescence spectral shift indicated changes in the tertiary structure. …”

Image 4_The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae.pdf by Bar Piscon (20906495)

“…These phenotypes are associated with repression of flagellin (fliC) transcription and a sharp decrease in the occurrence of conjugative pili in the presence of glycocholic acid, respectively.…”

Supplementary Material for: Underwater Clip Closure versus Conventional Clip Closure following Endoscopic Submucosal Dissection in Colorectal Lesions: A First Comparative Study by figshare admin karger (2628495)

“…Median closure time was significantly shorter in the UCC group (10 min [IQR, 7–14]) than in the CCC group (11 min [IQR, 8.5–19]; p = 0.044). …”