Table 5_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 1_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Data Sheet 1_Impact of hospital payment reform on rational use of antibiotics: a natural experiment.docx by Kun Zou (566767)

“…</p>Discussion<p>TDRG hospital payment reform may not affect the total quantity or expenditure of antibiotics use, but decrease the proportion of WHO Access antibiotics use and increase the Watch antibiotics use. …”

Signal denoising in modular spiking networks by Barna Zajzon (8083532)

“…We show that transmission accuracy increases as topographic projections become more structured, with even moderate degrees of modularity improving overall discrimination capability.…”

Supplementary file 1_Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling.pdf by Chun-Wei He (3909592)

“…We did not observe any change in baseline endocytosis; however, we did observe a significant decrease in recycling of GluA1-containing AMPARs in cultured hippocampal neurons from mice lacking SynDIG4. …”

Table1_Identification of key biomarkers and therapeutic targets in sepsis through coagulation-related gene expression and immune pathway analysis.docx by Jing Ge (443408)

“…<p>Sepsis, characterized by a widespread and dysregulated immune response to infection leading to organ dysfunction, presents significant challenges in diagnosis and treatment. In this study, we investigated 203 coagulation-related genes in sepsis patients to explore their roles in the disease. …”

Image 1_Comparative analysis of gut microbiota in metabolic syndrome and obese children from Southeastern China.jpeg by Jingjing Wang (140791)

“…At the class and genus levels, we found that the relative abundance of c_Gammaproteobacteria increased with weight, whereas c_Bacteroidia and g_Bacteroides decreased. …”

Identification of Alzheimer’s disease susceptibility genes by the integration of genomics and transcriptomics by Chenghong OuYang (13521682)

“…Through Mendelian randomization (MR) analysis, it was found that the risk of AD was significantly increased when VASP expression increased (OR = 0.1.046), while the risk of AD was significantly decreased when SURF2 (OR = 0.897) and TARBP1(OR = 0.920) expression increased. …”

Image 1_Formulation strategies of probiotics in broilers: systematic review and meta-analysis of their effects on production performance.tiff by Rafael Opazo (180430)

“…Researchers have also looked at factors such as probiotic dose (CFU/kg) and the number of strains in the Probiotic Mix, but these did not have a significant influence on heterogeneity. When converted combined effect sizes to metric units (g or kg), Lactobacillus showed the best results, with a 221.69 (g) increase in BWG and 0.17 (kg) decrease in FCR. …”

Image 2_Formulation strategies of probiotics in broilers: systematic review and meta-analysis of their effects on production performance.tif by Rafael Opazo (180430)

“…Researchers have also looked at factors such as probiotic dose (CFU/kg) and the number of strains in the Probiotic Mix, but these did not have a significant influence on heterogeneity. When converted combined effect sizes to metric units (g or kg), Lactobacillus showed the best results, with a 221.69 (g) increase in BWG and 0.17 (kg) decrease in FCR. …”

Data Sheet 1_Non-stationary response of Pacific saury (Cololabis saira) in the northwestern Pacific to climate variability.docx by Chang Cao (2592700)

“…The dynamics of Pacific saury from 1970 to 2021 could be divided into four periods: the 1970s and 1980s when the Siberian High and the intensification of the East Asian winter monsoon drove down the water temperature, providing a suitable habitat and resulting in an increase in resource abundance; In the 1990s, the rise in temperature led to a reduction in resource abundance; At the beginning of the 21st century, the enhancement of the Siberian High brought about a suitable habitat, and the resource abundance showed a significant increase; The unfavorable high water temperature environment in the 2010s caused the resource abundance to decrease once again. …”

Image 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.tiff by Junxian Hu (8158044)

“…CRT also exhibits distinct roles depending on its subcellular localization. In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. …”

Data Sheet 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.zip by Junxian Hu (8158044)

“…CRT also exhibits distinct roles depending on its subcellular localization. In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. …”

Data Sheet 1_Global burden and trends of occupational noise-induced hearing loss (1990–2021) and projection to 2040.pdf by Xin Gong (592328)

“…By 2040, ONIHL DALYs are predicted to increase, whereas the ASDR is projected to decrease; however, the disease burden among females will rise significantly.…”

Supplementary Material for: Focus on the Blind Spot of Stone Disease: Analysis of Lower Urinary Tract Stone Interventions from 2006 to 2020 using German nationwide inpatient data. by Herout R. (20352174)

“…Case numbers of percutaneous cystolithotripsy (PCCL) also increased over time from 406 to 430 cases (p=0.005), but the share decreased by 20 %. …”

Table 1_Effects of grassland degradation on soil ecological stoichiometry and soil microbial community on the South of the Greater Khingan Mountains.docx by Yuyu Li (3939137)

“…For fungal functional guilds, the relative abundance of pathotrophs increased while saprotrophs decreased significantly with increasing severity of degradation. …”

Table1_Tle6 deficiency in male mice led to abnormal sperm morphology and reduced sperm motility.docx by Kousuke Kazama (19937214)

“…In addition, Tle6^+/− mice exhibited a significant increase in serum testosterone levels compared to wild-type mice. …”

Data Sheet 1_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.xlsx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Data Sheet 2_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.docx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Image 1_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…This study employed a multi-omics approach, integrating single-cell and bulk RNA sequencing from 21 sepsis samples and Escherichia coli-induced sepsis datasets, alongside bioinformatics, machine learning, and experimental validation in a rat model and human peripheral blood. We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”