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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Accelerated dissolution testing for controlled release microspheres using the flow-through dissolution apparatus
Published 2008“…Increased flow rate also showed no detrimental effect on integrity. The effect of increased temperature was determined to be the statistically significant variable.…”
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Functionalized Metal Organic Frameworks For Chemotherapy Drug Delivery
Published 2020Get full text
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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A Probabilistic and Traffic-Aware Bundle Release Scheme for Vehicular Intermittently Connected Networks
Published 2012“…In this context, the design of effective delay-minimal data relaying strategies is receiving significant attention. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Comparative study of LNG, liquid hydrogen, and liquid ammonia post-release evaporation and dispersion during bunkering
Published 2024“…Based on the dispersion behaviours, the hazards of LNG and LH2 are comparable, while LNH3 poses significantly higher hazards. In terms of hazard mitigations, effective water curtain systems can suppress the vapour dispersion.…”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Zebrafish embryos were used as the animal model in this study to determine the effect of SPIONs-loaded NO-RPs on the cardiovascular system. …”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Zebrafish embryos were used as the animal model in this study to determine the effect of SPIONs-loaded NO-RPs on the cardiovascular system. …”
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Enhancing Curcumin’s therapeutic potential in cancer treatment through ultrasound mediated liposomal delivery
Published 2024“…CLs were effectively prepared with particles sized at 81 ± 2 nm, demonstrating stability and controlled release of curcumin under ultrasound exposure. …”
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Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry
Published 2025“…Free or monolayer carvacrol at 2% achieved reductions of 1.1–1.3 log CFU/g, while chlorine (50 ppm) was the least effective, with a reduction of 0.9 log CFU/g. These findings underscore the potential of nanoencapsulated carvacrol and <i>trans</i>-cinnamaldehyde as sustainable, eco-friendly, and effective solutions for enhancing poultry safety, mitigating antimicrobial resistance, and meeting consumer preferences for natural food preservation.…”
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Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound.
Published 2016Get full text
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”
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Effect of High-Frequency Ultrasound on Targeted Liposomes
Published 2022“…Delivering highly toxic drugs inside a safe carrier to tumors while achieving a controlled and effective drug release at the targeted sites represents an attractive approach to enhance drug efficiency while reducing its undesirable side effects. …”
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