DataSheet2_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.pdf حسب Yunxia Zhang (30848)

"…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. …"

DataSheet1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.docx حسب Yunxia Zhang (30848)

"…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. …"

Data Sheet 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx حسب Manling Zhang (566460)

"…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…"

Table 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx حسب Manling Zhang (566460)

"…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…"

Table 1_Epidemiological characteristics and trends of pre-hospital emergency care in Handan, China from 2011 to 2024.docx حسب Feng Tian (121350)

"…Over the past 14 years, Handan’s pre-hospital EMS demand increased significantly by 3.11-fold (p < 0.001). The percentages of EMS patients aged 61 to 70 and over 71 years old increased significantly (p < 0.01), in contrast, the percentage of EMS patients aged 21 to 30 and 31 to 40 years old decreased significantly (p < 0.01). …"

<b>Chemical components, emission dynamics, and external immune functions of red palm weevil larval volatiles in response to changes in developmental stages and pathogen stress</b> حسب Can-Hui Ding (22140753)

"…RPW larvae shared a number of volatile components across stages, but the emission dynamics were significantly different. …"

DataSheet1_The impact of statin use on short-term and long-term mortality in patients with heart failure.docx حسب Xiaoxue Zheng (433886)

"…Background<p>Heart failure (HF) is a complex disorder that has an association with increased morbidity and mortality rates globally. …"

Mitochondrial ROS generated by reverse electron transport in muscles is necessary for critical period heat stress to change NMJ development. حسب Daniel Sobrido-Cameán (5049743)

"…</i> 25°C control) leads to increased aCC NMJ terminal size and decreased postsynaptic GluRIIA, while not affecting subunit GluRIIB expression. …"

Table 3_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx حسب Yan Sun (22436)

"…The aim of this study is to determine whether implementing a patient-needs-enhanced Emergency Nursing Assessment Framework (ENAF), compared with usual care, increases the proportion of ED patients with non-traumatic chest pain receiving a 12-lead ECG within 10 min.…"

Table 1_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx حسب Yan Sun (22436)

"…The aim of this study is to determine whether implementing a patient-needs-enhanced Emergency Nursing Assessment Framework (ENAF), compared with usual care, increases the proportion of ED patients with non-traumatic chest pain receiving a 12-lead ECG within 10 min.…"

Table 2_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx حسب Yan Sun (22436)

"…The aim of this study is to determine whether implementing a patient-needs-enhanced Emergency Nursing Assessment Framework (ENAF), compared with usual care, increases the proportion of ED patients with non-traumatic chest pain receiving a 12-lead ECG within 10 min.…"

Knockdown of fatty acid binding protein 3 attenuates cerebral Ischemia-reperfusion injury <i>via</i> inhibiting neuronal apoptosis in mice حسب Jin-Jin Tian (22046330)

"…Recent studies have demonstrated that I/R significantly upregulates fatty acid binding protein 3(FABP3) expression, which has been shown to play a crucial role in mitochondrial dysfunction and neuronal apoptosis. …"

Data Sheet 1_NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma.pdf حسب Stephanie DeStefano (15457187)

"…Moreover, intranasal treatment with FITC-labelled OVA resulted in significantly higher allergen uptake by lung conventional dendritic cells (cDCs) in NLRP3^-/- compared to WT mice indicating increased epithelial leakiness. …"

Exogenous jasmonic acid alleviates Cu-induced damages in guinea grass by enhancing photosynthesis, antioxidant enzyme activity and modifying associated metabolites حسب Jian Ren (175424)

"…The results indicated that Cu stress significantly reduced superoxide dismutase (−51.2%) and peroxidase (−38.0%), chlorophyll content, net photosynthetic rate (<i>Pn</i>), and led to decreases in leaf length, width, plant height, and biomass (−49.7%). …"

Supplementary file 1_Parasite populations of river otter and mink in Western Canada, and the first report of the zoonotic trematode Alaria mustelae in river otter in North America.... حسب Kyle M. Shanebeck (21766418)

"…Increasing intensities of infection were significantly related to decreasing nutritional condition.…"

Data Sheet 1_Spleen tyrosine kinase inhibition mitigates radiation-induced lung injury through anti-inflammatory effects and downregulation of p38 MAPK and p53.pdf حسب Guoxing Zhang (4994213)

"…The levels of TGF-β, COL1A1, and α-SMA and degree of pulmonary fibrosis at 10 weeks after radiation were also decreased by Syk inhibitor.…"

<b>The Bacterial OMP Amyloids Modulate</b><b> </b><b>α</b><b>-Synuclein and Amyloid-</b><b>β</b><b> </b><b>Aggregation</b> حسب Maksim Sulatsky (21562922)

"…In contrast, amyloid-β fibrils showed more extensive structural changes, with modifications to both the "fuzzy coat" and β-sheet core, accompanied by decreased clustering tendency and significantly reduced toxicity for mammalian neuroblastoma and epithelial adenocarcinoma cell lines. …"

Data Sheet 1_Efficacy and safety of anlotinib combined with 125I seed implantation for iodine-refractory thyroid cancer.docx حسب Zhijun Chen (254277)

"…</p>Conclusion<p>Combining ¹²⁵I seed brachytherapy with anlotinib demonstrated superior short-term tumor control and prolonged local disease remission in RAIR-DTC, without increasing toxicity. This combination may offer a promising therapeutic option for RAIR-DTC, pending further validation in larger studies.…"

Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf حسب Juanjuan Zhang (432819)

"…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …"

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 حسب Arijit Ghosh (1304952)

"…Overexpression of kininogen and exogenous bradykinin administration significantly increased pentylenetetrazole-induced seizure susceptibility in mice. …"