Data Sheet 1_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Table 6_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.docx by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Data Sheet 3_Jian-Pi-Yi-Shen formula improves kidney function by regulating gut microbiome in rats with chronic kidney disease.csv by Yuzhi Wang (690944)

“…Adenine feeding induced significant GM shifts, evidenced by increased Aitchison distance (p < 0.01) and altered co-abundance interaction groups (CIGs): CIG3, 6, 9, 10 increased; CIG1, 2, 4, 12 decreased (all p < 0.05). …”

Image2_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”

Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx by Elisa Barbieri (115023)

“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”

<b>The Impact of Vitiligo on Pregnancy and Perinatal Outcome: A Systematic Review and Meta-analysis</b> by Lilia Maria Lima de Oliveira (21864683)

“…Pregnant women with vitiligo had a significantly higher chance of spontaneous abortion (OR 1.26; 95% CI [1.17, 1.36]), but a significantly lower chance of cesarean delivery (OR 0.93; 95% CI [0.87, 0.99]) than pregnant women without vitiligo. …”

Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx by Chengna Wang (21535973)

“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”

Cardiac function. by Gerald Yu Liao (20490394)

“…</b> Neither strain experienced age-related decreases in systolic/diastolic blood pressure, while CB6F1J mice trended higher readings compared to their C57BL/6J counterparts (*p < 0.05, **p < 0.01, N = 18-21/cohort for LVMI (tibia), N = 17-24/cohort for AO/LA ratio, N = 5-8/cohort for blood pressure).…”

Table 6_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx by Nirmal Parajuli (751983)

“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”

Supplementary Figure S2 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone by Chun-Lung Chiu (20972235)

“…Human PCa cells marked by Ku70 were significantly decreased after 30 days of treatment by intraperitoneal injection with batiraxcept (20 mg/kg/QOD, n = 8–9, docetaxel (10 mg/kg/QW, n = 9) or the combination of batiraxcept (20 mg/kg/QOD, n = 9) and docetaxel (10 mg/kg/QW, n = 9) compared to vehicle controls (n = 8,10). …”

Data Sheet 1_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.docx by Yanyao Lu (22163632)

“…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …”

Data Sheet 1_Association of body roundness index with cardiovascular disease in patients with cardiometabolic syndrome: a cross-sectional study based on NHANES 2009-2018.pdf by Xiaohua He (361530)

“…For CVD, stratified analyses did not show significant difference between strata. For CHF, BMI interacted with the association, with BRI being associated with decreased risk of CHF in a subgroup of normal weight subjects and increased risk of CHF in a subgroup of obese subjects. …”

Image3_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

Table 1_Retrospective case-control study of intraoperative EEG correlates in postoperative delirium.pdf by Longbiao Zhao (22045532)

“…No significant differences were observed in PSI values between the two groups. …”

Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d... by Jing Lu (120666)

“…</p>Conclusion<p>Higher SI is associated with a decreased risk of all-cause and cardiovascular mortality in CVD patients. …”

Table 4_Association between cardiovascular health and markers of liver function: a cross-sectional study from NHANES 2005–2018.docx by Huang Yu (5882174)

“…</p>Results<p>Linear regression analysis showed that each 1-point increase in CVH score was significantly associated with decreased levels of liver enzymes [ALT: −0.200 U/L (95% CI: −0.223, −0.176), AST: −0.043 U/L (−0.062, −0.024), GGT: −0.453 U/L (−0.509, −0.397), ALP: −0.310 U/L (−0.340, −0.281)] and increased levels of albumin [0.040 g/dL (0.036, 0.045)] and AST/ALT ratio [0.0056 (0.0051, 0.0061)]. …”

Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

“…</p>Results<p>Analysis of data from the 2011–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”

Data Sheet 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”

Image 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.tif by Man Zhao (314232)

“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”

Data Sheet 4_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”