يعرض 20,181 - 20,200 نتائج من 23,096 نتيجة بحث عن '(( significant ((a decrease) OR (fold increase)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.60s تنقيح النتائج
  1. 20181

    <i>Tmprss6</i> modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway حسب Ya-Li Zhou (21696911)

    منشور في 2025
    "…<p>Radiation-induced liver injury (RILI) poses a significant challenge in abdomino-pelvic tumor radiotherapy, adversely impacting normal liver tissues. …"
  2. 20182

    Data Sheet 1_How vanadium and manganese compounds impact cardiac mitochondrial function.pdf حسب Connor C. Dolan (21556343)

    منشور في 2025
    "…</p>Results and Discussion<p>Both vanadium and manganese salts decreased rates of mitochondrial respiration in a concentration dependent manner, which was attenuated when the metals were complexed to an organic ligand. …"
  3. 20183

    Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury.... حسب Pengyu Wang (6680312)

    منشور في 2025
    "…Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, has shown significant therapeutic benefits in clinical trials for the management of diabetes However, the specific mechanism on the treatment of diabetic liver injury with dapagliflozin is not fully understood. …"
  4. 20184

    Supplementary file 1_Effects of external diaphragm pacing combined with repetitive peripheral magnetic stimulation of the phrenic nerve on respiratory function in stroke patients.p... حسب Qin Zhang (58638)

    منشور في 2025
    "…In all three groups, CMAP amplitude increased significantly, whereas PNCT decreased significantly (p < 0.05). …"
  5. 20185

    Table 6_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  6. 20186

    Table 5_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  7. 20187

    Image 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  8. 20188

    Table 1_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf حسب Ying Xiao (6517)

    منشور في 2025
    "…Background<p>Pediatric infective endocarditis (IE) remains a rare but life-threatening condition, with substantial morbidity and mortality among children worldwide. …"
  9. 20189

    Table 3_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf حسب Ying Xiao (6517)

    منشور في 2025
    "…Background<p>Pediatric infective endocarditis (IE) remains a rare but life-threatening condition, with substantial morbidity and mortality among children worldwide. …"
  10. 20190

    Image 1_Multi-omics analysis reveals indicator features of microbe-host interactions during Candida albicans colonization and subsequent infection.tif حسب Huan Zhang (220065)

    منشور في 2024
    "…</p>Importance<p>Candida albicans invasive infections pose a significant challenge to contemporary medicine, with mortality rates from such fungal infections remaining high despite antifungal treatment. …"
  11. 20191

    Table2_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease... حسب Juan Tang (437969)

    منشور في 2024
    "…Age effects across all countries and genders demonstrated an increasing trend over time, indicating age as a significant risk factor for IHD. Moreover, period and cohort effects in higher SDI countries exhibited a more rapid decline in both genders compared to lower SDI countries. …"
  12. 20192

    Data Sheet 1_Linarin alleviates colonic barrier dysfunction induced by enterotoxic Escherichia coli in weaned piglets by regulating the gut microbiota and metabolic pathways.docx حسب Qianqian Zhang (587342)

    منشور في 2025
    "…Introduction<p>Enterotoxigenic Escherichia coli (ETEC) is a globally recognized gastrointestinal pathogen and a major cause of diarrhea in neonatal and post‐weaning animals, leading to significant economic losses in pig production. …"
  13. 20193

    Table1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease... حسب Juan Tang (437969)

    منشور في 2024
    "…Age effects across all countries and genders demonstrated an increasing trend over time, indicating age as a significant risk factor for IHD. Moreover, period and cohort effects in higher SDI countries exhibited a more rapid decline in both genders compared to lower SDI countries. …"
  14. 20194

    Datasheet1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of dis... حسب Juan Tang (437969)

    منشور في 2024
    "…Age effects across all countries and genders demonstrated an increasing trend over time, indicating age as a significant risk factor for IHD. Moreover, period and cohort effects in higher SDI countries exhibited a more rapid decline in both genders compared to lower SDI countries. …"
  15. 20195

    Evolutionary tree analysis of ZmSTOMAGEN. حسب Juan-Juan Xu (18590868)

    منشور في 2025
    "…Compared to the wild-type plants (HiII-A × HiII-B), the <i>zmstomagen1/2</i> mutant exhibited significant alterations in phytohormone homeostasis. …"
  16. 20196

    The relationship between early-onset preeclampsia and the prognostic nutritional index and inflammatory markers حسب Alev Esercan (19818890)

    منشور في 2024
    "…</p> <p>In our case control study, 70 patients with early-onset preeclampsia and 140 pregnant women composed the normotensive (control) group. There was a significant difference between the groups according to PIV (p = 0.04). …"
  17. 20197

    Image 1_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif حسب Wei Liu (20030)

    منشور في 2025
    "…In vitro, KSG mitigated Aβ<sub>25-35</sub>-induced cytotoxicity in PC12 cells, decreased Aβ accumulation, and downregulated the expression of TNF-α and IL-1β. …"
  18. 20198

    Data Sheet 1_Yeast culture improves growth, antioxidant status, immunity, and gut microbiota homeostasis in preweaning Holstein calves.csv حسب Xueqiang Li (614522)

    منشور في 2025
    "…Immunoglobulin and cytokine levels were also significantly higher in the YC group (p < 0.05). Metagenomic analysis revealed a significant increase in the Chao index and a trend toward higher Shannon diversity in the YC group. …"
  19. 20199

    Raw data for all figures. حسب Juan-Juan Xu (18590868)

    منشور في 2025
    "…Compared to the wild-type plants (HiII-A × HiII-B), the <i>zmstomagen1/2</i> mutant exhibited significant alterations in phytohormone homeostasis. …"
  20. 20200

    Image 2_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif حسب Wei Liu (20030)

    منشور في 2025
    "…In vitro, KSG mitigated Aβ<sub>25-35</sub>-induced cytotoxicity in PC12 cells, decreased Aβ accumulation, and downregulated the expression of TNF-α and IL-1β. …"