DataSheet_2_Integrated physiological and metabolomic responses reveal mechanisms of Cd tolerance and detoxification in kenaf (Hibiscus cannabinus L.) under Cd stress.xlsx by Wajid Saeed (12216596)

“…</p>Methods<p>In this study, the effects of different Cd concentrations (0, 100, 250, and 400 µM) on growth, biomass, Cd uptake, physiological parameters, metabolites and gene expression response of kenaf were investigated in a hydroponic experiment.</p>Results and discussion<p>The results showed that Cd stress significantly altered the ability of kenaf to accumulate and transport Cd; increased the activity of hydrogen peroxide (H₂O₂), superoxide anion (O₂⁻), and malondialdehyde (MDA); reduced the activities of superoxide dismutase (SOD) and catalase (CAT); and decreased the content of photosynthetic pigments, resulting in significant changes in growth and biomass production. …”

DataSheet_1_Overexpression of DBT suppresses the aggressiveness of renal clear cell carcinoma and correlates with immune infiltration.zip by Chiyu Zhang (119192)

“…Our findings suggest that DBT is a distinct predictive biomarker for KIRC patients, playing a significant role in the TME of KIRC and serving as a reference for the selection of targeted treatment and immunotherapy.…”

Image_2_Primary and memory immune responses against rough Brucella canis are less robust compared to smooth B. abortus and B. melitensis following intratracheal infection in mice.t... by Lauren W. Stranahan (6811013)

“…However, B. canis induced significantly less granulomatous inflammation in the spleen as well as a lack of bronchial-associated lymphoid tissue (BALT) hyperplasia in the lungs. …”

Video_1_Mapping of the supplementary motor area using repetitive navigated transcranial magnetic stimulation.MP4 by Giulia Kern (16009760)

“…Further, the lower extremity was mapped at 20 Hz (140%RMT) using a toe tapping task.</p>Results<p>Mean finger tapping scores decreased significantly during stimulation (25.70taps) compared to baseline (30.48; p < 0.01). …”

Image2_Relation between CarS expression and activation of carotenogenesis by stress in Fusarium fujikuroi.pdf by Macarena Ruger-Herreros (6249311)

“…The assayed stressors increase the synthesis of carotenoids in the three strains, but mRNA levels of structural genes of carotenogenesis, carRA and carB, are only enhanced in the presence of a functional carS gene. In the wild-type strain, the four conditions affect in different manners the mRNA levels of carS: greater in the presence of light, without significant changes in nitrogen starvation, and with patent decreases after heat shock or oxidative stress, suggesting different activation mechanisms. …”

Video5_Evaluation of women’s aging influence on sperm passage inside the fallopian tube using 3D dynamic mechanical modeling.MP4 by Mayssam Nassir (18351408)

“…Thus, the changes that the human fallopian tube undergoes due to women’s aging have a significant influence on the human sperm cell motility. …”

DataSheet1_Osthole/borneol thermosensitive gel via intranasal administration enhances intracerebral bioavailability to improve cognitive impairment in APP/PS1 transgenic mice.docx by Fanchang Wu (16538070)

“…Osthole assisted by borneol demonstrated significantly improved efficiency in suppressing cleaved caspase-3 expression, increasing the Bcl-2/Bax ratio, improving T-SOD and catalase expression, reducing malondialdehyde levels, inhibiting neuron apoptosis, and decreasing Aβ levels by inhibiting BACE1 expression to alleviate cognitive impairment in APP/PS1 mice compared to osthole alone. …”

Table 2_Untargeted metabolic analysis in serum samples reveals metabolic signature in children with congenital heart failure on enalapril therapy.csv by N. J. L. Smeets (21188726)

“…Patients were defined as responder when aldosterone levels decreased after a single administration of enalapril. …”

Image_1_Microbiome Profiling Reveals Gut Dysbiosis in the Metabotropic Glutamate Receptor 5 Knockout Mouse Model of Schizophrenia.pdf by Carolina Gubert (9576788)

“…We found a significant genotype difference in microbial beta diversity. …”

DataSheet_1_Integrated physiological and metabolomic responses reveal mechanisms of Cd tolerance and detoxification in kenaf (Hibiscus cannabinus L.) under Cd stress.docx by Wajid Saeed (12216596)

“…</p>Methods<p>In this study, the effects of different Cd concentrations (0, 100, 250, and 400 µM) on growth, biomass, Cd uptake, physiological parameters, metabolites and gene expression response of kenaf were investigated in a hydroponic experiment.</p>Results and discussion<p>The results showed that Cd stress significantly altered the ability of kenaf to accumulate and transport Cd; increased the activity of hydrogen peroxide (H₂O₂), superoxide anion (O₂⁻), and malondialdehyde (MDA); reduced the activities of superoxide dismutase (SOD) and catalase (CAT); and decreased the content of photosynthetic pigments, resulting in significant changes in growth and biomass production. …”

Video_2_Mapping of the supplementary motor area using repetitive navigated transcranial magnetic stimulation.MP4 by Giulia Kern (16009760)

“…Further, the lower extremity was mapped at 20 Hz (140%RMT) using a toe tapping task.</p>Results<p>Mean finger tapping scores decreased significantly during stimulation (25.70taps) compared to baseline (30.48; p < 0.01). …”

Image_1_Coated Zinc Oxide Improves Growth Performance of Weaned Piglets via Gut Microbiota.TIF by Yiwei Sun (4897975)

“…In addition, C_ZnO also led to a significant increase of acetate and propionate in both foregut and hindgut. …”

Prediction of drug combinations for potential new screen for neurodegenerative disorders. by Jeremy Grignard (12963351)

“…The detyrosination rate constant <i>k</i>₁ is decreased by a factor one hundred at 60 units of time (min). …”

Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and... by Dilpreet Kour (10872766)

“…Subsequent brain tissue analysis revealed that IBC upregulated autophagic proteins to reduce the brain’s amyloid beta levels, resulting in decreased expression of neuroinflammation markers.</p>Conclusion<p>IBC effectively ameliorates AD pathology through autophagy-mediated clearance of Aβ and suppressing neuroinflammation in 5x-FAD mice.…”

Image1_Cytotoxicity of Amphotericin B and AmBisome: In Silico and In Vivo Evaluation Employing the Chick Embryo Model.TIF by Ahmad Khosravi (525161)

“…<p>Leishmaniasis has been identified as a significant disease in tropical and subtropical regions of the world, with Iran being one of the disease-endemic areas. …”

Table_1_Microbiome Profiling Reveals Gut Dysbiosis in the Metabotropic Glutamate Receptor 5 Knockout Mouse Model of Schizophrenia.pdf by Carolina Gubert (9576788)

“…We found a significant genotype difference in microbial beta diversity. …”

Table 1_Untargeted metabolic analysis in serum samples reveals metabolic signature in children with congenital heart failure on enalapril therapy.csv by N. J. L. Smeets (21188726)

“…Patients were defined as responder when aldosterone levels decreased after a single administration of enalapril. …”

Image_1_Systemic Ketone Replacement Does Not Improve Survival or Cancer Cachexia in Mice With Lung Cancer.png by Henning Tim Langer (12749483)

“…Finally, we investigated PPARα activity in the liver of mice fed KE and NC and found that animals fed a ketone ester supplement showed a significant increase in mRNA expression of several PPARα targets. …”

Video1_Evaluation of women’s aging influence on sperm passage inside the fallopian tube using 3D dynamic mechanical modeling.MP4 by Mayssam Nassir (18351408)

“…Thus, the changes that the human fallopian tube undergoes due to women’s aging have a significant influence on the human sperm cell motility. …”

Image_4_Primary and memory immune responses against rough Brucella canis are less robust compared to smooth B. abortus and B. melitensis following intratracheal infection in mice.t... by Lauren W. Stranahan (6811013)

“…However, B. canis induced significantly less granulomatous inflammation in the spleen as well as a lack of bronchial-associated lymphoid tissue (BALT) hyperplasia in the lungs. …”