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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
all decrease » small decrease (Expand Search), fold decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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17981
Image 4_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg
Published 2025“…Background<p>The tumor microenvironment (TME) plays a critical role in the development, progression, and clinical outcomes of hepatocellular carcinoma (HCC). …”
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17982
Image 3_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg
Published 2025“…Background<p>The tumor microenvironment (TME) plays a critical role in the development, progression, and clinical outcomes of hepatocellular carcinoma (HCC). …”
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17983
Image 1_The replication protein of duck circovirus unwinds dsDNA in an ATP-driven and metal ion-dependent manner from 3′ to 5′.pdf
Published 2025“…The results indicated that Rep had a 3′–5′ unwinding directionality, and Rep was capable of unwinding dsDNA with a 3′-overhang of not less than 1 nt. …”
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17984
Image_1_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.PNG
Published 2024“…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …”
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17985
Data Sheet 1_The protective effects and mechanisms of rosmarinic acid against Pseudomonas aeruginosa infection in Caenorhabditis elegans.doc
Published 2025“…Introduction<p>Pseudomonas aeruginosa poses a significant risk to both the environment and organisms. …”
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17986
Data Sheet 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf
Published 2025“…The known fusion KANSL1-ARL17A/B occurred with a high frequency in 69% of the patients. …”
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17987
Table 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.xlsx
Published 2025“…The known fusion KANSL1-ARL17A/B occurred with a high frequency in 69% of the patients. …”
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17988
Supplementary Materials -Table
Published 2025“…<p dir="ltr">Exposure to hypobaric hypoxia during rapid ascent to high altitudes significantly impacts intestinal barrier function. Goblet cells, as one of the primary cell types in the intestinal mucosa, play a crucial role in maintaining this barrier. …”
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17989
Image 5_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg
Published 2025“…Background<p>The tumor microenvironment (TME) plays a critical role in the development, progression, and clinical outcomes of hepatocellular carcinoma (HCC). …”
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17990
Image 2_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif
Published 2025“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
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17991
Data Sheet 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf
Published 2025“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
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17992
Table 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx
Published 2025“…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …”
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17993
Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
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17994
Table 1_Safety and efficacy of canine recombinant IL-15 in mammary gland tumors.docx
Published 2025“…Sixty-one client-owned dogs were initially enrolled, and 55 completed the 12-week study. Dogs were assigned to a test group receiving rcIL-15 with surgery or a control group undergoing surgery alone. …”
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17995
Hesperetin attenuates ischemia/reperfusion-induced acute kidney injury by regulating ferroptosis in mice
Published 2025“…Ferroptosis markers showed that hesperetin decreased levels of ACSL4 while increasing GPX4, FTH1, and SLC7A11, suggesting an anti-ferroptotic effect. …”
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17996
Raw Data.
Published 2025“…<div><p>Immune dysregulation is a pathogenic factor in ulcerative colitis (UC), in which mitochondrial involvement is increasingly recognized. …”
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17997
Table 2_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.xlsx
Published 2025“…The known fusion KANSL1-ARL17A/B occurred with a high frequency in 69% of the patients. …”
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17998
Table 1_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.docx
Published 2024“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”
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17999
Table 1_DKK3 and SERPINB5 as novel serum biomarkers for gastric cancer: facilitating the development of risk prediction models for gastric cancer.docx
Published 2025“…Significant biomarkers in GC patients were identified by DIA combined ELISA, including elevated Keratin 7 (KRT7) and Mammary fibrostatin (SERPINB5) (P<0.001) and decreased Dickkopf-associated protein 3 (DKK3) (P<0.001). …”
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18000
Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”