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19061
Supplementary Material for: Impact of the apolipoprotein E ε4 allele on cognition and omega-3 fatty acid levels in the plasma membrane of red blood cells in healthy elderly Japanes...
Published 2025“…The ratio of docosahexaenoic acid (DHA) to arachidonic acid was significantly decreased, and the erythrocyte eicosapentaenoic acid (EPA) and DHA levels tended to be reduced in APOE4 carriers. …”
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19062
Table 1_Lipid biomarkers of GVHD in allogeneic stem hematopoietic cell transplantation patients.docx
Published 2025“…</p>Results<p>Profound dyslipidemia was observed post-transplantation, with over 60% of patients developing significantly decreased high-density lipoprotein cholesterol (HDL-C) and elevated triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) compared to baseline. …”
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19063
Raw data for main and supplemental figures
Published 2025“…This effect was accompanied by reduced expression of genes encoding known LEE regulators, including protein factors (<i>ihfA</i> and <i>hns</i>) and sRNAs (GlmY and GlmZ), resulting from decreased stability of their transcripts in the absence of <i>proQ</i>. …”
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19064
Table 1_Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury.docx
Published 2025“…</p>Methods<p>Using transcriptome sequencing in a mouse model of IIRI, we identified potential biomarkers that were significantly upregulated in the IIRI group compared to the sham group. …”
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19065
Data Sheet 1_Study of pain perception under negative emotions and its large-scale brain network dynamics in adolescents with non-suicidal self-injury.zip
Published 2025“…Conversely, the occurrence frequency of microstate B decreased markedly. Under neutral emotion induction, the MDD group exhibited higher occurrence frequency of microstate A and transition rate from microstate D→A than the HC group. …”
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19066
Long-term prognostic value of thyroid hormone levels in chronic critical illness patients
Published 2025“…This study aimed to investigate the predictive value of the nonthyroidal illness syndrome (NTIS) for the prognosis of CCI patients, establish a predictive model for the prognosis of CCI patients, and evaluate the efficacy of the model to provide a theoretical basis for clinical intervention.…”
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19067
Candidate genes by Genome-wide CRISPR Screen.
Published 2024“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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19068
Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat...
Published 2025“…<p>Curcuma angustifolia Roxb. is a therapeutic herb and a member of the Zingiberaceae family. …”
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19069
Table5_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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19070
Table4_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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19071
Table2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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19072
Table3_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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19073
Table1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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19074
Table6_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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19075
Vasculogenic mimicry in melanoma tissue : immunohistochemistry, cell growth & morphological assays, migration & invasion assays and protein expression analyses
Published 2025“…<p dir="ltr">This dataset supports a study investigating the role of vasculogenic mimicry in melanoma through both in vivo and in vitro approaches. …”
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19076
Supplementary Material for: Reduction of waste mass in used hemodialysis circuits by QCC activity
Published 2025“…Results: Implementation of QCC interventions resulted in a 29.7% reduction in mean circuit mass, decreasing from 0.64±0.015 kg to 0.45±0.012 kg (p<0.01) across the sampled hemodialysis apparatus. …”
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19077
Table 8_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx
Published 2025“…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…”
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19078
Table 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.xlsx
Published 2025“…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…”
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19079
Table 1_The RNA-binding protein ProQ directly binds and regulates virulence genes in enterohemorrhagic Escherichia coli O157:H7.docx
Published 2025“…This effect was accompanied by reduced expression of genes encoding known LEE regulators, including protein factors (ihfA and hns) and sRNAs (GlmY and GlmZ), resulting from decreased stability of their transcripts in the absence of proQ. …”
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19080
Image 2_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg
Published 2025“…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…”