Image2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.tif by Yifang He (18126257)

“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”

Data Sheet 1_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx by Stephanie Dauth (13274397)

“…Significant between-group differences were observed for changes in some parameters at day 4 (e.g., IL-10) and day 14. …”

Table 1_Regulation effect of seed priming on sowing rate of direct seeding of rice under salt stress.pdf by Yicheng Zhang (790286)

“…Our results demonstrated that under T1–T3, the germination rate, α-amylase activity, and soluble sugar and protein contents were significantly increased after priming treatments. The contents of reactive oxygen species (i.e., O₂⁻ and H₂O₂) and malondialdehyde (MDA) were decreased, while the activities of enzymatic antioxidants (i.e., superoxide dismutase, peroxidase, and catalase) and the K⁺/Na⁺ ratio of rice were significantly increased after the above seed priming treatments. …”

Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

“…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m², while it decreased by 11.4ml/min/1.73 m² in the RNU group (WMD, 11.81 ml/min/1.73 m²; 95%CI,9.06-14.56; P<0.0001).…”

Data Sheet 1_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.... by Yuxuan Zhang (1425721)

“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”

Data Sheet 4_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... by Yu Zhang (12946)

“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”

Data Sheet 3_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... by Yu Zhang (12946)

“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”

Supplementary file 1_Comparative efficacy of femoral neck system vs. cannulated compression screws in young patients with femoral neck fractures: a systematic review and meta-analy... by Weishuai Zhang (22399933)

“…Meta-analysis revealed that, compared to CCS, FNS was associated with a significantly shorted fracture healing time (SMD = 16.30, 95% CI: 3.79–28.82, P < 0.001), decreased intraoperative fluoroscopy usage (WMD) = −8.14, 95% CI: −9.82 to −6.46, P < 0.001), and higher Harris hip scores at the final follow-up (WMD = −3.43, 95% CI: −4.08 to −2.77, P < 0.001). …”

Data_Sheet_1_Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study.docx by Mengyuan Chen (5633153)

“…Both lower and higher SII levels (either continuous or categorical variable) were significantly associated with an increased risk of malnutrition.…”

Table 5_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx by Jianwei Hong (6918776)

“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”

Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

“…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…”

Table 1_Effect of compound kushen injection on immune function in patients with colorectal cancer: a systematic review and meta-analysis.docx by Lixin Zhang (55947)

“…Chemotherapy and radiotherapy remain cornerstone treatments; however, they often lead to significant immune suppression and an increased risk of infection. …”

Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... by Wenjing He (4278625)

“…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …”

Table 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Table 4_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Image 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.tif by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Repetitive stress modulates loudness perception. by Ghattas Bisharat (20706928)

“…Mice exhibited increased perceptual boundaries during repeated stress, indicating a decreased loudness perception (<i>t</i> test, <i>p</i> = 1.2 × 10⁻⁰⁵, mean ± SE). …”

Data Sheet 1_Real world evidence of dupilumab effectiveness in a Colombian cohort of patients diagnosed with severe asthma.docx by Abraham Alí-Munive (21347201)

“…FEV₁pp showed higher but not significant values from the 2–4-month period, with a median change of 12.5% (IQR: 0.3, 21.5). …”

Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”

Table 1_Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks.docx by Chen Shaopeng (20576303)

“…Introduction<p>The gut microbiota significantly influences the host’s production performance and health status, with different gastrointestinal tissues exhibiting functional diversity reflected in their microbial diversity.…”