Data Sheet 1_Perilipin 5 alleviates ferroptosis of cardiomyocytes by targeting USP10-p53-TfR proteasome-dependent degradation.docx by Jianqiao Zhao (14519036)

“…</p>Results<p>We found that after MI, cardiac subcellular iron levels increased and the expression of PLIN5 decreased. Overexpression of PLIN5 reduced lipid peroxidation, enhanced ferroptosis resistance, decreased iron accumulation, and lowered TfR expression. …”

Data Sheet 2_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx by Yang Yu (4292)

“…TaERF13-2B overexpression in Arabidopsis resulted in significantly reduced survival rates under drought conditions with decreased expression of stress-responsive and antioxidant enzyme genes, indicating that the TaERF13-2B gene elevated drought sensitivity in transgenic Arabidopsis. …”

Data for Will et al. 2025 Resting metabolic rate is repeatable, but does not affect call characteristics, in the gray treefrog <i>Hyla chrysoscelis</i> by Phoebe Will (20819362)

“…Nevertheless, RMR was significantly repeatable. We found that RMR decreased across the breeding season, which reduced the consistency in RMR measurements of the same individual over time. …”

Table 1_Nitric oxide regulates photosynthesis and the capacity of the antioxidant system under water deficit and rehydration in Lolium multiflorum/Festuca arundinacea introgression... by Dawid Perlikowski (648680)

“…Moreover, the plants with a lower NO content were characterized by a significantly higher water uptake in the early stages of water deficit progression, which could disturb their drought tolerance. …”

Data Sheet 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc by Yaojin Sun (21692411)

“…</p>Results<p>Post-treatment, median HEAD-US-C scores decreased from 5.00 to 1.00 (P < 0.001), and HJHS 2.1 scores decreased from 9.00 to 2.00 (P < 0.001). …”

Iron biofortification of <i>Pleurotus eous</i> via substrate supplementation by D. Leena Lavanya (21676675)

“…The results showed that while calcium and boron levels have decreased, a few minerals, including sodium, potassium, phosphorus, magnesium, zinc, and copper, have increased significantly (<i>p</i> < .05). …”

Efficacy and safety of trastuzumab deruxtecan in HER2-high and HER2-low breast cancer: a systematic review and meta-analysis of randomized controlled trials by Sheng-Yen Hsiao (9939006)

“…However, T-DXd increased the risks of interstitial lung disease (relative risk [RR] = 13.832; P < 0.001), decreased left ventricular ejection fraction (RR = 2.247; P < 0.001), anemia, nausea, vomiting, decreased appetite, and alopecia; neutropenia and diarrhea risks were comparable between groups. …”

Data Sheet 1_Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation.docx by Sarvatit Patel (5558792)

“…<p>Aging significantly affects intercellular communication between vascular endothelial cells (ECs) and hematopoietic cells, leading to vascular inflammation and age-associated diseases. …”

Table 1_Impact of recent COVID-19 infection on liver and kidney transplantation – a worldwide meta-analysis and systematic review.docx by Nicola Sariye Pollmann (22327573)

“…Nevertheless, an association was found with decreased overall survival in liver transplant recipients within the 180-day follow-up period.…”

Paiva et al. data by Sergio Nogueira-Filho (10808859)

“…Specifically, haemoglobin concentration decreased 24 hours after ozone therapy, MCHC levels increased seven days post-ozone therapy, and serum AST activity decreased seven days post-ozone therapy. …”

Deleterious Effects of a GAD65 Monoclonal Autoantibody on Islet Function by Christiane S. Hampe (248347)

“…GAD65mAb also reduced insulin secretion <i>in vivo</i> where decreased insulin levels after IP injection of glucose were observed in rats after IP injection of GAD65mAb. …”

Data Sheet 1_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx by Yang Yu (4292)

“…TaERF13-2B overexpression in Arabidopsis resulted in significantly reduced survival rates under drought conditions with decreased expression of stress-responsive and antioxidant enzyme genes, indicating that the TaERF13-2B gene elevated drought sensitivity in transgenic Arabidopsis. …”

Table 1_Exogenous jasmonic acid and salicylic acid enhance selenium uptake and mitigate cadmium accumulation in pak choi (Brassica chinensis L.) grown in selenium-rich, high-cadmiu... by Jin-Ping Chen (6003755)

“…Cd accumulation in shoots decreased by 11.7%-29.3% in JA-containing treatments, with the same combined producing the lowest shoot Cd levels. …”

Image 1_Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11.tif by Li Ling (424480)

“…Moreover, the combination of SAS and ¹³¹I significantly increased the MDA levels and lipid peroxidation, decreased the GSH levels, and suppressed the expression of SLC7A11 and GPX4, while SLC7A11 knockdown significantly enhanced ferroptosis-related markers in DTC cells. …”

Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc by Zhenghao Wu (9732511)

“…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …”

Data Sheet 1_Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implicatio... by Liming Liu (107470)

“…Immunophenotyping revealed a GCB-like phenotype in HALs, characterized by elevated CD10 and BCL6 expression and decreased MUM1 and BCL2 expression. Patients with HALs had significantly shorter survival (median: 32.1 vs. 46.1 months, P < 0.001). …”

Image 3_VdPAT1 encoding a pantothenate transporter protein is required for fungal growth, mycelial penetration and pathogenicity of Verticillium dahliae.jpeg by Stephen Mwangi Kamau (20576060)

“…Chitin and β-1,3-glucan content determination found that the chitin content in VdPAT1 deletion mutants was significantly lower, while β-1,3-glucan content was higher than that of wild-type and complementary strains. …”

Image 2_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.jpeg by Zetong Zheng (22069658)

“…LH, but not E2, significantly induced AQP2 expression in LGCs in a dose-dependent manner. …”

Data Sheet 1_Evaluating the prognostic relevance of neutrophil-to-lymphocyte ratio in cervical cancer: a systematic review and meta-analysis.docx by Xieyan Zhuang (20467625)

“…</p>Conclusion<p>An elevated NLR prior to treatment demonstrates a strong association with decreased OS and PFS among patients with cervical cancer, underscoring the significance of NLR as a prognostic marker within this population.…”

Data Sheet 5_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf by Erdengqieqieke Ye (19542808)

“…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …”