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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
fold increased » fold increase (Expand Search)
all decrease » small decrease (Expand Search), a decrease (Expand Search), fold decrease (Expand Search)
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19661
Table 1_Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway.docx
Published 2025“…</p>Results<p>The results demonstrated that Ir-1 exhibited significant radiosensitizing effects on lung cancer cells. …”
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19662
Image 3_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.pdf
Published 2025“…</p>Results<p>Patients with SLE exhibited significantly decreased MMP-Low in some peripheral lymphocyte subsets. …”
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19663
Framework synthesis of zinc scale-up programs.
Published 2025“…Our findings demonstrate the long-term success of the SUZY project and provide insights into best practices for impactful zinc scale-up programs including significant pre-launch implementation research addressing key knowledge gaps and partnering with research organizations. …”
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19664
Table 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx
Published 2025“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”
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19665
Table 1_Neural correlates of subjective cognitive decline in Alzheimer’s disease: a systematic review of structural and functional brain changes for early diagnosis and interventio...
Published 2025“…Dynamic functional connectivity studies report reduced brain activity efficiency, while graph theory analyses show decreased network integration. Advanced neuroimaging techniques and machine learning (ML) approaches demonstrate significant promise in detecting subtle neural changes in SCD, with applications for early diagnosis and monitoring disease progression.…”
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19666
Data Sheet 1_Adjunctive esketamine in propofol-based sedation for gastrointestinal endoscopy: a systematic review and meta-analysis of randomized trials.docx
Published 2025“…No significant differences were found for hypertension, arrhythmias, PONV, recovery time or dizziness.…”
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19667
Supplementary file 1_Spatiotemporal monitoring in beidagang wetland using Landsat time-series images and Google Earth Engine during 2000–2022.docx
Published 2025“…Frequent type conversions occurred between adjacent classes, with the most significant changes in Guanqi Lake. Despite declining wetland water volumes due to rising temperatures and reduced precipitation, ecological compensation measures, including functional zoning, water replenishment, and phragmites restoration, have continuously improved the wetland environment. …”
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19668
Table 1_Serum neurotransmitter analysis of motor and non-motor symptoms in Parkinson’s patients.docx
Published 2024“…Analysis of neurotransmitter metabolism revealed significant changes in the tryptophan (Trp) metabolic pathway in PD patients. …”
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19669
Data Sheet 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”
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19670
Table 6_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls
Published 2025“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”
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19671
Image 2_The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis...
Published 2025“…The results showed that antioxidant supplementation significantly alleviated pelvic pain (continuous outcomes: SMD = −2.68; p < 0.00001; binary outcomes: RR = 9.31; p < 0.0001), dysmenorrhea (SMD = −1.77; p = 0.01; RR = 2.39; p = 0.03), and dyspareunia (SMD = −2.33; p = 0.01; RR = 5.40; p = 0.003), and significantly decreased peripheral blood malondialdehyde (MDA) levels (SMD = −7.58; p = 0.001). …”
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19672
Data_Sheet_1_Depression and health literacy among adolescents and adults in Germany: findings from two representative samples.pdf
Published 2024“…Introduction<p>Depressive disorders constitute a significant public health challenge. Health literacy might be an important factor to consider in prevention strategies for depressive disorders, which is why this study aimed at exploring the association between depressive symptom levels and severity and health literacy, along with additional sociodemographic factors.…”
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19673
Data Sheet 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.pdf
Published 2025“…ARL5B expression was significantly downregulated in treated Y79 and Weri-RB1 cells. …”
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19674
Image 1_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg
Published 2025“…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”
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19675
Table 1_Effects of singing on vascular health in older adults with coronary artery disease: a randomized, crossover trial.docx
Published 2025“…When assessing post- to pre- change, the live singing intervention showed a significant change of −0.62 ms<sup>2</sup> (SE 0.29, p = 0.036) in LnHF power.…”
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19676
Lower serum LH level was related to poor embryo quality and adverse pregnancy outcomes in fixed GnRH antagonist protocol with estradiol pretreatment
Published 2024“…After adjusting for AMH and AFC, the impacts were not significant. As LH<sub>trigger</sub> increased, E<sub>2</sub>/oocytes and good-quality embryo rate increased and peaked in T4 and implantation rate increased and peaked in T3. …”
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19677
Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus
Published 2025“…</p> <p>Compared to the HC group, SLE patients exhibited a decline in both Lyn mRNA and protein expression in PBMCs, with significant downregulation in the high SLEDAI group versus the low SLEDAI group and a notable reduction in the LN group relative to the non-LN group. …”
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19678
Low-speed Rear-end Collisions: Kinematic and Clinical Responses (Video, MRI findings, EMG/NCS results)
Published 2025“…While 58.3% of participants reported immediate post-collision pain, this decreased to 25% within a week, primarily affecting the cervical spine and lower back.…”
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19679
Image 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.png
Published 2025“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”
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19680
Data Sheet 1_The effects of urbanization on human-viper conflicts and the natural history and impacts of removal operations for Protobothrops mucrosquamatus in Northeast Taiwan.doc...
Published 2025“…This suggests that the development of such infrastructure significantly impacts the occurrence of these conflicts. …”