Data Sheet 1_Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study.pdf by Paulo Rodrigues-Santos (3424613)

“…Gene expression analysis identified changes in BTRC (decreased), IFNA1 (increased), and IL9 (increased) in PD versus SD patients (p<0.05). …”

Data Sheet 3_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf by Lu Ding (475637)

“…Metabolite analysis revealed associations between decreased proline, isoleucine, valine, and alanine levels with IS. …”

Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Experimental and Numerical Investigations of Soot Formation in the Laminar to Turbulent Transition of an Acetylene Diffusion Flame by Shijun Chen (835302)

“…Soot formation from incomplete hydrocarbon combustion poses significant challenges for emission control in propulsion systems. …”

Image 2_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.jpeg by ZhengFeng Fan (20950202)

“…The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. The findings suggest that SlERF4-9 plays a significant role in root growth and development. …”

Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 1_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.xlsx by ZhengFeng Fan (20950202)

“…The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. The findings suggest that SlERF4-9 plays a significant role in root growth and development. …”

Table 1_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Image 4_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disease St... by Chenjing Xu (12109035)

“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”

Table 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.docx by Lichao Cao (276107)

“…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …”

Identification of a Novel Virulence Factor in <i>Klebsiella pneumoniae</i> through CpxR-Dependent Transcriptional Activation by Runze Wang (21792959)

“…Among the genes exhibiting significantly decreased expression upon <i>cpxR</i> deletion<i>, </i>we identified a novel potential virulence factor KPHS_28080. …”

Data Sheet 7_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The fractal dimension D₂ and D₃ values of pores in the medium and macropores scale range are close to 3, with the maximum value of D₂ being 2.971. This indicates significant fractal characteristics, suggesting that medium pores are the most developed in this scale range. …”

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 1_The real-world safety of Nivolumab: a pharmacovigilance analysis based on the FDA adverse event reporting system.docx by Yutong Wu (3130584)

“…The most frequently reported AEs included fatigue, dyspnea, musculoskeletal pain, decreased appetite, cough, nausea, and constipation. …”

Data Sheet 4_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The fractal dimension D₂ and D₃ values of pores in the medium and macropores scale range are close to 3, with the maximum value of D₂ being 2.971. This indicates significant fractal characteristics, suggesting that medium pores are the most developed in this scale range. …”

Data Sheet 3_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The fractal dimension D₂ and D₃ values of pores in the medium and macropores scale range are close to 3, with the maximum value of D₂ being 2.971. This indicates significant fractal characteristics, suggesting that medium pores are the most developed in this scale range. …”

Table 3_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf by Ziqin Feng (22318243)

“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”

Table 1_Mediation effects of metabolites and sex hormones on the relationship between body mass index and breast cancer: Mendelian randomization analysis and mediation analysis.xls by Yanjiang Yang (13860452)

“…</p>Results<p>The IVW model indicated significant negative causal correlations between BMI and BC, ER⁺BC, and ER^-BC. …”

Image 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …”

Image 3_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disease St... by Chenjing Xu (12109035)

“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”