<i>trus</i> mutant displays higher embryonic lethality. by Saeko Takada (21616085)

“…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”

DataSheet1_Network meta-analysis of integrated traditional Chinese and Western medicine in the treatment of Sjogren’s syndrome.pdf by Xieli Ma (20153298)

“…</p>Conclusion<p>TCM combined with CWM has a very significant effect on treating SS compared with CWM alone. …”

Data Sheet 1_The efficacy of ophiopogonanone B in treating the cough in mice infected with Mycoplasma pneumoniae.docx by Nan-Nan Liu (12093551)

“…</p>Conclusion<p>By decreasing the expression of TRPA1, SP, and CGRP in the lung tissues of mice afflicted with coughing due to M. pneumoniae infection, ophiopogonanone B effectively alleviated post-infection cough symptoms.…”

raw data by Boya Gao (21686150)

“…Bacterial abundance under moderate and extreme disturbances was significantly lower than that in the control, whereas fungal abundance was significantly higher under extreme disturbance. …”

Table_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…</p>Results<p>Analysis of data from the 2007–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”

Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study by Klaus G. Parhofer (12280424)

“…</p> <p>Among 1565 patients, LDL-C levels decreased from 91.0 mg/dL at baseline to 73.5 mg/dL at 6 months and 71.5 mg/dL at 12 months. …”

Image 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.tif by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Table 7_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls by Meizhi Liu (21898892)

“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”

Table 1_Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer.xlsx by Xiucheng Jiang (18849564)

“…Notably, mitochondrial haplogroup D4 was significantly associated with a decreased risk of developing EC. …”

Image 1_Metformin enhances alpelisib sensitivity in HER2+ breast cancer by suppressing cancer stemness and oncogenic signaling.tif by Yujie Shi (737203)

“…Combination treatment induced significant G0/G1 cell-cycle arrest, reduced ALDH1⁺ populations, and decreased tumorsphere formation. …”

Table 4_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Image 2_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg by Kaisong Huang (5412626)

“…In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …”

DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

The atrium and ventricle exhibit different tissue dynamics during morphogenesis. by Juliana Sánchez-Posada (20636677)

“…Total endocardial volume decreases after 58 hpf (D), driven by a reduction in endocardial tissue in both the atrium and ventricle (E); 34–36 hpf: <i>n</i> = 9; 48–50 hpf: <i>n</i> = 10; 58–60 hpf: <i>n</i> = 8; 72–74 hpf: <i>n</i> = 10. …”

Image 1_Application and validation of the machine learning-based multimodal radiomics model for preoperative prediction of lateral lymph node metastasis in papillary thyroid carcin... by Jia-Wei Feng (10754067)

“…Current diagnostic methods show significant limitations, with occult LLNM rates of 41.0%-51.7% requiring secondary surgeries. …”

Table_4_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.docx by Ling Li (38566)

“…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …”

Table1_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.pdf by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”

Image1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”