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Elemental distributions in the marine sediments off Doha, Qatar: role of urbanisation and coastal dynamics
Published 2024“…On the other hand, the dust deposits have caused significant contributions to the Al, As, Mg, Ca, Sr, Fe, Zn, and Cd concentrations. …”
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A clustering metaheuristic for large orienteering problems
Published 2022“…The Orienteering Problem is a challenging NP-hard problem, such that obtaining optimal or near optimal solutions usually requires a significant amount of computation for large and even moderately large instances. …”
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…</p><h3>Results</h3><p dir="ltr">Shade analysis revealed that, in the short term, HP treatment significantly increased lightness and Hue and decreased chroma compared to DW (<i>p </i>< 0.05); however, 1 week after treatment some of the initial gains in tooth lightness were partially lost. …”
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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment
Published 2020“…In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …”
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A snapshot of current medical research: The notion of supply and demand
Published 2017“…Research has never been more in demand and pursued by various health disciplines worldwide as it is at present. Contemplating the amount, type and quality of current medical research over the last decade leads one to consider the driving forces behind such research. …”
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Hepatoprotective Effect of Oleuropein-Rich Extract from Olive Leaves against Cadmium-Induced Toxicity in Mice
Published 2020“…Results showed that Cd induced a significant increase in liver injury biomarkers coupled with enhanced lipid peroxidation (MDA) and significant depletion of antioxidants (CAT and SOD). …”
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The effect of foeniculum vulgare seeds on lipidemia, glycemia & liver enzymes. (c2009)
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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
Published 2023“…We first confirmed the identity of the isolated exosomes to have their specific markers (CD63, CD81, HSP70 and CD91). We have demonstrated that baseline concentration of exosomal-PD-L1 (p<0.0001), exosomal-PD-L2 (p=0.0413) and exosomal-PD-1 (p=0.0131) from NSCLC patients were significantly higher than their soluble-free forms. …”
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Downregulation of Lymphoid enhancer‐binding factor 1 (<i>LEF‐1)</i> expression (by immunohistochemistry and/ flow cytometry) in chronic Lymphocytic Leukemia with atypical immunophe...
Published 2020“…Absence of <i>LEF-1</i> expression in CLL/SLL is correlated (<i>P</i> < .05) with downregulation of CD5, CD23, CD200, expression of FMC7, brighter expression of CD79b, brighter expression of surface light chain, increased prolymphocytes and lower Matutes score.…”
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Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report
Published 2023“…<h3>Background</h3><p dir="ltr">Autoimmune lymphoproliferative syndrome (ALPS) is a rare disease characterized by defective FAS signaling, which results in chronic, nonmalignant lymphoproliferation and autoimmunity accompanied by increased numbers of “double-negative” T-cells (DNTs) (T-cell receptor αβ+ CD4−CD8−) and an increased risk of developing malignancies later in life.…”
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
Published 2002“…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …”
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Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy
Published 2023“…</p><h2>Results</h2><p dir="ltr">DAC treatment significantly upregulated stemness markers in both primary 1076 Col and meta-static 1872 Col cell lines, although a lower effect occurred on the latter: CD44 (7.85 fold; ***p = 0.0001 vs. (4.19 fold; *p = 0.0120), Nanog (4.1 fold; ***p < 0.0001 vs.1.69 fold; ***p = 0.0008), KLF-4 (4.33 fold; ***p < 0.0001 vs.2.48 fold; ***p = 0.0005), CD133 (16.77 fold; ***p = 0.0003 vs.6.36 fold; *p = 0.0166), and MSI-1 (2.33 fold; ***p = 0.0003 vs.2.3 fold; ***p = 0.0004), respectively. …”
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Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine
Published 2020“…Exposure to Cd increases the risk of cardiovascular disease by disrupting vascular homeostasis at the endothelium. …”
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Nurses’ work environment and intent to leave in Lebanese hospitals
Published 2011“…Regression analysis revealed that for every 1 point score decrease on career development there was a 93% increase in likelihood of reporting intent to leave country. …”
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Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles
Published 2024“…Overall, the results of this study showed that embedding a small amount of Co<sup>2+</sup> ions doped ZnO NPs with PSf has significant potential to be applied in industrial-scale membrane applications.…”
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Circular economy application for a Green Stadium construction towards sustainable FIFA world cup Qatar 2022™
Published 2021“…<p dir="ltr">The construction industry is responsible for a significant amount of raw material consumption and environmental footprints. …”
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Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound
Published 2021“…HA conjugation to the liposomes resulted in a significant increase in calcein uptake by the breast cancer cell line MDA-MB-231 known for its CD44 (HA receptor) overexpression, while such an effect was not recorded with NIH-3T3, an embryonic mouse fibroblast, with low levels of CD44 expression. …”
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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells
Published 2008“…The p-STAT3 inhibitor WP1066 enhanced CD3+ (which contained Tregs) but not CD8+ T cell cytotoxicity against human A375 melanoma cells, indicating that this p-STAT3 blockade agent did not directly activate CD8+ T cells. …”
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