Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties حسب Mesmar, Joelle

"…Non-cytotoxic concentrations of OSEE attenuated cell proliferation and induced G0/G1 cell cycle arrest, which was associated with phosphorylation of p38 MAPK, an increase in the levels of tumor suppressor protein p21, and a decrease of proliferation marker protein Ki67. Additionally, only higher concentrations of OSEE were able to attenuate inhibition of proliferation induced by the ROS scavenger N-acetyl cysteine (NAC), indicating that the anti-proliferative effects of OSEE could be ROS-dependent. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A vector quantization based k-NN approach for large-scale image classification حسب Ozan, Ezgi Can

"…However, with the growth of the size of image datasets and the number of dimensions of image descriptors, popularity of k-NNs has decreased due to their significant storage requirements and computational costs. …"
احصل على النص الكامل
احصل على النص الكامل

INVESTIGATING THE MOLECULAR MECHANISMS UNDERLYING THE ANTI-CANCER ACTIVITIES OF DIOSMETIN IN COLORECTAL CANCER CELLS: AN IN VITRO STUDY حسب AHMED, SABAH NISAR

"…The results revealed that Diosmetin exerts significant cytotoxic effects on HCT116 cells as indicated by decreased cell viability and proliferation, increased DNA damage, loss of mitochondrial membrane potential (MMP), cell cycle arrest, and induction of apoptosis. …"
احصل على النص الكامل

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…Notable COX-2 inhibitory activities (IC50 = 0.065–0.24 μM) were observed relative to celecoxib (IC50 = 0.049 μM). The two most effective 15-LOX inhibitors, 2a and 2b, exhibited 69 % and 57 % of quercetin's action, respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Thymus vulgaris (Thyme) inhibits proliferation, adhesion, migration, and invasion of human colorectal cancer cells حسب Al-Menhali, Afnan

"…Therefore, T. vulgaris could have an anticancer effect and that some of its bioactive compounds may prove to be effective treatment modalities for human CRC.…"
احصل على النص الكامل
احصل على النص الكامل

Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy حسب Ahmed, Ashraf Ibrahim

"…Results: STZ rats exhibited behavioral signs of mechanical and heat hypersensitivity as indicated by significant decreases in the mean paw withdrawal threshold (PWT) and mean paw withdrawal latency (PWL), respectively, at 35 days post-STZ treatment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

NOVEL HIGHLY ANTIBACTERIAL CORROSION RESISTANT NIP-CEO2-C3N4 NANO-COMPOSITE COATINGS حسب ARRO, CHRISTIAN RANDELL

"…Furthermore, the shape of C3N4 significantly influences its corrosion resistance values. …"
احصل على النص الكامل

NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs حسب Posadino, Anna Maria

"…Sera from SSc patients showed significant changes in the expression of a set of fibrosis/EndMT-associated microRNAs (miRNA), including miR-21, miR-92a, miR-24, miR-27b, miR-125b, miR-29c, and miR-181b, which resulted significantly upregulated as compared to healthy donors sera. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway حسب Hadrich, F.

"…In vivo model, the oral administration of oleuropein at 50 mg/kg in rats fed with high fat diet for 8 weeks reduced inflammation in liver and adipose tissues (WAT), improved glucose intolerance, and decreased hyperinsulinemia. Furthermore, the immunohistochemistry revealed that the expression level of p-Akt, IRS1, and Glut-4 were significantly enhanced in liver and WAT tissues after oleuropein supplementation comparing with that in HFD group. …"
احصل على النص الكامل
احصل على النص الكامل

Long-Distance Vowel-to-Vowel Coarticulation in Arabic: Influences of Intervening Consonant Pharyngealization and Length حسب Ahmed, Sarah

"…In contrast, one speaker showed significant vowel-to-vowel effects at all three measured distances that were effectively blocked in the pharyngealized consonant condition.…"
احصل على النص الكامل
احصل على النص الكامل

Capital structure and debt maturity: Evidence from listed companies in Saudi arabia حسب Abdullah, Abdul Kader M. A.

"…The relationship between asset maturity and long term debt was found to be negative and significant. Therefore, there is no support of the hypothesis that debt maturity decreases as the proportion of growth potentials increase. …"
احصل على النص الكامل

Solar hydrogen production via a samarium oxide-based thermochemical water splitting cycle حسب Bhosale, Rahul

"…Furthermore, the recuperation of heat for the operation of the cycle significantly improves the solar reactor efficiency. …"
احصل على النص الكامل
احصل على النص الكامل

Hybrid wind-diesel-battery system planning considering multiple different wind turbine technologies installation حسب Rakhshani, E.

"…Adopting a well-structured planning model is one of the most effective ways to further reduce costs and been the focus of research in the past decades. …"
احصل على النص الكامل
احصل على النص الكامل

Continuous adsorptive removal of glimepiride using multi-walled carbon nanotubes in fixed-bed column. حسب Badran, ismail

"…The results showed that the drug removal is improved with the increasing bed height; however, it decreased with the flow rate. The effect of pH indicated that the adsorption is significantly affected and increased in acidic medium. …"
احصل على النص الكامل
احصل على النص الكامل

Computational modeling of motile cilia generated cerebral flow dynamics in zebrafish embryo حسب Salman, Huseyin Enes

"…The angle of ciliary beating significantly affected the flow velocity. As the angle between the wall and cilia decreases, the flow becomes more efficient by achieving higher velocities. …"
احصل على النص الكامل
احصل على النص الكامل

Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells حسب AlKahlout, Amal

"…We also show that OSE significantly promoted homotypic cell-cell adhesion while it decreased cellular migration, adhesion to fibronectin, and invasion of MDA-MB-231 cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

NUMERICAL INVESTIGATION OF THE POTENTIAL OF USING HYDROGEN AS AN ALTERNATIVE FUEL FOR AN INDUSTRIAL BURNER حسب QAZAK, ABDUL HAFIZ

"…In addition, NOx emission levels rise as the total fuel MFR decreases, but it starts to reduce as the total fuel MFR increases. …"
احصل على النص الكامل

A short-term probabilistic photovoltaic power prediction method based on feature selection and improved LSTM neural network حسب Liu, Ronghui

"…Coupled Input and Forget Gate(CIFG) network is proposed to minimize structure without significantly decreasing the prediction accuracy. Furthermore, a new hybrid method combining Quantile Regression(QR) and CIFG network is proposed to predict the conditional quantile of PV output. …"
احصل على النص الكامل
احصل على النص الكامل

Methane production enhancement from Tetraselmis biomass co-digestion using frying oil residue as co-substrate and ultrasonication as pretreatment حسب Firas, Feki

"…However, increasing specific energy sonication to 3.2 kJ/g VS decreased the positive energy balance of whole process from 8.6 to 5.5 ± 0.3 kJ/g VS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Methane production enhancement from Tetraselmis biomass co-digestion using frying oil residue as co-substrate and ultrasonication as pretreatment حسب Firas, Feki

"…However, increasing specific energy sonication to 3.2 kJ/g VS decreased the positive energy balance of whole process from 8.6 to 5.5 ± 0.3 kJ/g VS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل