Image_2_An in vitro Model of Human Retinal Detachment Reveals Successive Death Pathway Activations.tif by Jelena Potic (9693587)

“…Tissues were studied at different time points and immunohistological analyses for TUNEL, Cleaved caspase3, AIF, CDK4 and the epigenetic mark H3K27me3 were performed. …”

Image_1_The Role of Lactate Exercise Test and Fasting Plasma C-Peptide Levels in the Diagnosis of Mitochondrial Diabetes: Analysis of Clinical Characteristics of 12 Patients With M... by Yuan Zhao (336512)

“…The optimal cut-off points identified were 5.5 and 3.4 mmol/L for plasma lactate levels immediately after and 30 minutes after exercise, respectively. …”

Data_Sheet_1_Impaired Hippocampal Neurovascular Coupling in a Mouse Model of Alzheimer’s Disease.PDF by Lin Li (28817)

“…Importantly, we found a significantly increased Ca²⁺ uncaging-induced ROS production in APP mice. …”

Table_1_Optimal LC-MS metabolomic profiling reveals emergent changes to monocyte metabolism in response to lipopolysaccharide.xlsx by Emma Leacy (9352040)

“…In the untargeted analysis, 154 metabolite entities were significantly altered compared to unstimulated cells. …”

Table3_Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach.XLSX by Philip Vlummens (221451)

“…At later time points, apoptosis occurred, as evidenced by increased AnnexinV-positivity and cleavage of PARP and caspases. …”

Image_1_An in vitro Model of Human Retinal Detachment Reveals Successive Death Pathway Activations.tif by Jelena Potic (9693587)

“…Tissues were studied at different time points and immunohistological analyses for TUNEL, Cleaved caspase3, AIF, CDK4 and the epigenetic mark H3K27me3 were performed. …”

Image_3_An in vitro Model of Human Retinal Detachment Reveals Successive Death Pathway Activations.tif by Jelena Potic (9693587)

“…Tissues were studied at different time points and immunohistological analyses for TUNEL, Cleaved caspase3, AIF, CDK4 and the epigenetic mark H3K27me3 were performed. …”

Data_Sheet_1_Macrophages Down-Regulate Gene Expression of Intervertebral Disc Degenerative Markers Under a Pro-inflammatory Microenvironment.docx by Ana J. Silva (6906773)

“…Accumulating evidence suggests that inflammation plays a crucial role in the progression of human IVD degeneration, with macrophages being pointed as the key immune cell players in this process since their infiltration in degenerated IVD samples has been extensively demonstrated. …”

Image_4_An in vitro Model of Human Retinal Detachment Reveals Successive Death Pathway Activations.tif by Jelena Potic (9693587)

“…Tissues were studied at different time points and immunohistological analyses for TUNEL, Cleaved caspase3, AIF, CDK4 and the epigenetic mark H3K27me3 were performed. …”

Table1_Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach.XLSX by Philip Vlummens (221451)

“…At later time points, apoptosis occurred, as evidenced by increased AnnexinV-positivity and cleavage of PARP and caspases. …”

Table_1_Breath Stable Isotope Analysis Serves as a Non-invasive Analytical Tool to Demonstrate Dietary Changes in Adolescent Students Over Time.pdf by Christy J. Mancuso (11995214)

“…After-lunch δ¹³C_breath values decreased significantly between the two time points, suggesting an increase in whole grain, fruit, and vegetable carbohydrates in the lunch program. …”

Data_Sheet_1_Proenkephalin A and bioactive adrenomedullin are useful for risk prognostication in cardiac surgery.pdf by Aileen Hill (11976616)

“…</p>Results<p>In 136 patients undergoing cardiac surgery, the bio-ADM levels increased and the penKid levels decreased significantly over time. PenKid was associated with chronic kidney disease (CKD), the incidence of AKI, and renal replacement therapy (RRT). …”

Data_Sheet_1_MiR-29a Increase in Aging May Function as a Compensatory Mechanism Against Cardiac Fibrosis Through SERPINH1 Downregulation.PDF by Evelyn Gabriela Rusu-Nastase (11957507)

“…In vitro analysis of miR-29a effects on fibroblast and cardiac muscle cells pointed toward a protective role of miR-29a on aging-related fibrosis, by reducing cell migration and proliferation. …”

Optimisation of read depth, DNA quantity, and unique alternate observation threshold. by Melinda L. Tursky (20790436)

“…Lower read depth may contribute to an overestimated VAF of very small variants, although differences did not reach significance. D-F: Blood samples from 383 community-dwelling subjects were sequenced at a target depth of 3,000-4,000 × . …”

Dendritic arborization defects caused by MCAO in M1 are completely reverted during the days after the ischemic event in both layer II/III and layer V neurons of the ipsilateral hem... by Yuanyuan Ji (455424)

“…Note that dendritic branching points (<b>E</b>), dendritic terminal points (<b>F</b>), total dendritic tree length (<b>G</b>), and Sholl intersections (<b>H–J</b>) were all decreased upon MCAO after 24 hours but were fully recovered to values indistinguishable from the corresponding sham controls after 4 days and 7 days reperfusion, respectively. …”

<i>Cobl</i> KO mice fail to show repair of the dendritic arborization defects caused by MCAO in both layer II/III and layer V neurons of the ipsilateral hemisphere. by Yuanyuan Ji (455424)

“…Note that dendritic branching points (<b>E</b>), dendritic terminal points (<b>F</b>), total dendritic tree length (<b>G</b>), and Sholl intersections (<b>H-J</b>) were all decreased at 24 hours after MCAO and that, in contrast to WT animals (<b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001399#pbio.3001399.g005" target="_blank">Fig 5</a></b>), none of these phenotypical parameters recovered during the days after MCAO in <i>Cobl</i> KO mice. …”

Table_1_Epigenetic Modulation of Class-Switch DNA Recombination to IgA by miR-146a Through Downregulation of Smad2, Smad3 and Smad4.pdf by Paolo Casali (489340)

“…In miR-146a^–/– mice, the elevated systemic IgA levels were associated with increased IgA⁺ B cells in intestinal mucosae, increased amounts of fecal free and bacteria-bound IgA as well as kidney IgA deposition, a hallmark of IgA nephropathy. …”

Table 1_Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact.docx by Yi Cao (229829)

“…In contrast, the estradiol content in the skin of the physical contact group was significantly lower, with levels of 65.87 ± 32.75, 59.06 ± 24.99, 7.95 ± 4.89, and 12.09 ± 3.71 at the same time points. …”

Table_2_Chronic Microglial Activation in the GFAP-IL6 Mouse Contributes to Age-Dependent Cerebellar Volume Loss and Impairment in Motor Function.DOCX by Erika Gyengesi (6549689)

“…In addition, TNF-α levels proved to be significantly higher in the GFAP-IL6 compared to WT mice at all time points. …”

Table_1_In vitro Cytotoxicity and Pharmacokinetic Evaluation of Pharmacological Ascorbate in Dogs.DOCX by Margaret L. Musser (7829228)

“…Ascorbate (75 pmoles/cell) significantly decreased survival in both the osteosarcoma cell lines (D-17 63% SD 0.010, P = 0.005; OSCA-8 50% SD 0.086, P = 0.026), compared to normal fibroblasts (27% SD 0.056).…”