Showing 21,921 - 21,940 results of 22,098 for search '(( significant ((binding decrease) OR (binding database)) ) OR ( significant decrease decrease ))', query time: 0.45s Refine Results
  1. 21921

    Table 5_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx by Chao-Chao Chen (21090215)

    Published 2025
    “…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
  2. 21922

    Image 6_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... by Chao Song (379006)

    Published 2025
    “…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…”
  3. 21923

    Data Sheet 1_The Syringe Pump Gas Distribution (SPGD) system: a simple and low-cost method for simulating NH3/15NH3 deposition.docx by Chunze Wu (14348715)

    Published 2025
    “…The cost, complexity, and risk associated with simulating NH<sub>3</sub> deposition can be significantly decreased by utilizing the SPGD system. …”
  4. 21924

    Table 6_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... by Yun Xu (139234)

    Published 2025
    “…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
  5. 21925

    Image 3_Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a... by Zeyan Liu (3748747)

    Published 2025
    “…Background<p>Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. …”
  6. 21926

    Table 1_Pingwei Powder alleviates high-fat diet-induced colonic inflammation by modulating microbial metabolites SCFAs.xlsx by Tangjuan Liu (2634649)

    Published 2025
    “…Experimental validation showed that PWP significantly downregulated the levels of PI3K, pAKT/AKT, and pmTOR/mTOR in colonic tissue, thereby enhancing autophagy in colonic epithelial cells, as evidenced by decreased levels of P62 and increased LC3B-II/LC3B-I ratios. …”
  7. 21927

    Table 3_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... by Yun Xu (139234)

    Published 2025
    “…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
  8. 21928

    Data Sheet 1_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... by Junhong Yang (7807046)

    Published 2025
    “…Finally, donors from outdoor blood collection sites (0.590%) and groups (1.073%) were at a significantly higher risk of syncope compared to those from indoor blood donation sites (0.438%) and individual donors (0.174%).…”
  9. 21929

    Image 6_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... by Yun Xu (139234)

    Published 2025
    “…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
  10. 21930

    Dataset. by Wanjun Zhang (496858)

    Published 2025
    “…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …”
  11. 21931

    Image 3_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... by Yun Xu (139234)

    Published 2025
    “…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
  12. 21932

    Table 4_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.xlsx by Siying Wei (5990276)

    Published 2025
    “…However, the pandemic significantly slowed the decline in low- and low-middle SDI regions.…”
  13. 21933

    Table1_Seed priming with ascorbic acid and spermidine regulated auxin biosynthesis to promote root growth of rice under drought stress.docx by Kangkang Zhang (3367442)

    Published 2024
    “…The mitigating effects of AsA or Spd priming on drought stress were primarily responsible for decreasing the accumulation of reactive oxygen species by increasing antioxidants activities and osmoprotectants contents, which reduced oxidative stress and osmotic cell potential and facilitated improved water and nutrients absorption in roots. …”
  14. 21934

    Image 3_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... by Khalidah Ibraheem (9525220)

    Published 2025
    “…</p>Results<p>Chemotherapy agents reduced keratinocyte viability at 37°C by ∼65%–70%, induced HF dystrophy evident by decreased proliferation (9% Ki-67+ cells), increased apoptosis (23% TUNEL+ cells), and reduced anagen (∼10%) and pigmentation. …”
  15. 21935

    Image_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... by Mingzheng Duan (11630632)

    Published 2024
    “…However, continuous cropping of this species has led to various obstacles, such as microbial disease and pest infestation, significantly affecting the production and development of valuable medicinal and food resources. …”
  16. 21936
  17. 21937

    Dupilumab improves sense of smell and clinical outcomes in patients with severe chronic rhinosinusitis with nasal polyps with anosmia by Andrew P. Lane (20367704)

    Published 2024
    “…<p>Loss of sense of smell is a cardinal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP) and significantly impacts health-related quality-of-life. …”
  18. 21938

    Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets by Karl Knipper (15016346)

    Published 2025
    “…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …”
  19. 21939

    Data Sheet 1_Strategies for enhancing yield and quality of forage-grain dual-purpose ratoon rice: role of first-season density and nitrogen management.docx by Yuyuan Ouyang (15350374)

    Published 2025
    “…Results showed that: Silage yield increased significantly with higher density and nitrogen input. …”
  20. 21940

    Table2_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx by Runzhou Ma (19758996)

    Published 2024
    “…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10<sup>-4</sup>, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10<sup>-5</sup>, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…”