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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
bins decrease » point decrease (Expand Search), sizes decrease (Expand Search), nn decrease (Expand Search)
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18241
Table 6_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18242
Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls...
Published 2024“…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …”
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18243
Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx
Published 2025“…The use of intravenous thrombolysis decreased (52.4% to 40.4%; p<sub>trend</sub><0.01). …”
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18244
Table 2_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18245
C2CD3 is crucial for the localization of the LDR and DISCO complexes.
Published 2025“…Centriole diameter was not significantly altered (siCTRL: <i>n</i> = 44, 115 ± 24 nm; siC2CD3: <i>n</i> = 44, 123 ± 27 nm; <i>P</i> = 0.0564). …”
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18246
DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx
Published 2024“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”
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18247
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”
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18248
A Locally Linear Dynamic Strategy for Manifold Learning.
Published 2025“…In contrast to alignment modulation, the change in the spectrum is largely non-selective. exhibits no significant change for both signal-oriented (blue) and noise-oriented (orange) modes. …”
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18249
Image 1_First-trimester choroid plexus-to-head ratio: a novel sonographic marker for the early detection of fetal central nervous system malformations.jpeg
Published 2025“…Compared with the control group, scatter diagrams and box-and-whiskers plots showed ventriculomegaly (VM) fetuses had significantly decreased CPA/HA and CPL/OFD ratios (p < 0.001), but increased CFD/OFD and HC/AC ratios (p < 0.001). …”
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18250
Image 2_First-trimester choroid plexus-to-head ratio: a novel sonographic marker for the early detection of fetal central nervous system malformations.jpeg
Published 2025“…Compared with the control group, scatter diagrams and box-and-whiskers plots showed ventriculomegaly (VM) fetuses had significantly decreased CPA/HA and CPL/OFD ratios (p < 0.001), but increased CFD/OFD and HC/AC ratios (p < 0.001). …”
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18251
Table 4_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18252
Table 3_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18253
Table 1_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18254
Table 5_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18255
Table 2_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18256
<b>Distributed Hydraulic Micro-Cooling (MHD): A Low-Cost, High-Impact Urban Heat Mitigation Strategy</b> / <b>Enfriamiento Hidráulico Micro-Distribuido (MHD): Estrategia Urbana de...
Published 2025“…Large thermal masses such as roofs, asphalt roads, and concrete structures store significant amounts of solar radiation during the day (up to 1200–1600 MJ/m²). …”
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18257
DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx
Published 2025“…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…”
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18258
Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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18259
Cued-attention is mediated by a cholinergic HDB to SAC circuit.
Published 2025“…Inset denotes glomeruli with significant changes with SAC inhibition. Yellow: increased, dark grey: decreased, light grey: unchanged. …”
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18260
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi...
Published 2025“…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I<sup>2</sup> = 23%) in patients with SGLT-2i treatment compared with non-users. …”