IRE1 silencing downregulates cell cycle genes and engages TP53 and specific CDK inhibitors. حسب Iratxe Zuazo-Gaztelu (21071939)

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IRE1 silencing downregulates cell cycle genes and engages TP53 and specific CDK inhibitors. حسب Iratxe Zuazo-Gaztelu (21071939)

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Pharmacological efficacy of Kylo-0603 in MASH mouse models (F2 ~ 3). حسب Xueqin lu (22250795)

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General procedure for the synthesis of B. حسب Xueqin lu (22250795)

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The trends of gene expression in the metabolism of triglycerides in liver tissue. حسب Xueqin lu (22250795)

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After 8 weeks of treatment, body fat analysis and bone mineral density testing of mice in each group. حسب Xueqin lu (22250795)

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The trends of cholesterol metabolism-related gene expression in liver tissue. حسب Xueqin lu (22250795)

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Kylo-0603’s EC50 & tissue levels. حسب Xueqin lu (22250795)

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The Chol and TG content in liver homogenates of the mice in each group after 2 and 10 weeks of drug intervention. حسب Xueqin lu (22250795)

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The trends in the expression of inflammation-related genes in liver tissue. حسب Xueqin lu (22250795)

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The Fibrosis scoring by Sirius Red staining and SHG/TPEF. حسب Xueqin lu (22250795)

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Effects of Kylo-0603 on body weight, organ weight, and body fat content. حسب Xueqin lu (22250795)

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The trends in the expression of fibrosis-related genes in liver tissue. حسب Xueqin lu (22250795)

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Effects of Kylo-0603 on the expression of related genes of the MASH mouse models. حسب Xueqin lu (22250795)

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Plasma cholesterol and LDL-C levels. حسب Xueqin lu (22250795)

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General procedure for the synthesis of A and A-c1. حسب Xueqin lu (22250795)

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Hematoxylin and eosin (H&E) staining, Sirius Red staining, and Oil Red staining of liver tissues from mice in each group after 8 weeks of treatment with either vehicle or Kylo-0603... حسب Xueqin lu (22250795)

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DIO Mice Liver Staining. حسب Xueqin lu (22250795)

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Trends of peroxisome-related gene expression in liver tissue. حسب Xueqin lu (22250795)

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NAS (NAFLD Activity Score) of liver tissue of mice in each group after 8 weeks of treatment with either vehicle (V) or Kylo-0603 (0.1-10 mg/kg/day). حسب Xueqin lu (22250795)

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