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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
cause decrease » caused decreased (Expand Search), causes increased (Expand Search)
use decreased » use increased (Expand Search), rate decreased (Expand Search), cost decreased (Expand Search)
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20221
Image 4_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg
Published 2025“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
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20222
Table1_Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.pdf
Published 2024“…These findings underscore the potential significance of inflammatory factors and metabolites in the genetic underpinnings of OSA development and prognosis.…”
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20223
Data Sheet 1_Differential regulation of soil microecology in crop rotation systems of maize, seed pumpkin, and processing tomato.docx
Published 2025“…Notably, the SLa treatment significantly decreased soil total potassium content by 13.6%. …”
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20224
Image 2_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg
Published 2024“…Overall survival (OS) and progression-free survival (PFS) were analyzed using the Kaplan–Meier method and compared using log-rank tests. …”
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20225
Image 1_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg
Published 2024“…Overall survival (OS) and progression-free survival (PFS) were analyzed using the Kaplan–Meier method and compared using log-rank tests. …”
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20226
Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx
Published 2025“…In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…”
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20227
Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke
Published 2025“…Hence, the present study explored changes in the ubiquitinomic in early ischemic brain tissues between wildtype and ENOPH1 knockout mice using a comprehensive quantitative analysis. Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”
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20228
Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke
Published 2025“…Hence, the present study explored changes in the ubiquitinomic in early ischemic brain tissues between wildtype and ENOPH1 knockout mice using a comprehensive quantitative analysis. Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”
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20229
Image 2_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif
Published 2025“…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
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20230
Table 1_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.docx
Published 2025“…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
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20231
Image 1_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif
Published 2025“…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
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20232
Image 3_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif
Published 2025“…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
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20233
Supplementary file 1_tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2.doc
Published 2025“…The effects of tRF-1:28-Val-CAC-2 on the growth and distant metastasis of tumors were then tested in vivo using nude mice.</p>Results<p>NPC cells exhibited tRF-1:28-Val-CAC-2 upregulation that was associated with significantly increased proliferative, migratory, and invasive activity together with the suppression of apoptotic death. …”
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20234
Supplementary file 2_tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2.doc
Published 2025“…The effects of tRF-1:28-Val-CAC-2 on the growth and distant metastasis of tumors were then tested in vivo using nude mice.</p>Results<p>NPC cells exhibited tRF-1:28-Val-CAC-2 upregulation that was associated with significantly increased proliferative, migratory, and invasive activity together with the suppression of apoptotic death. …”
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20235
Data Sheet 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx
Published 2025“…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …”
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20236
Data Sheet 1_Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microb...
Published 2025“…</p>Results<p>In vitro studies demonstrated that TMG significantly inhibited proliferation and promoted apoptosis in CT26.WT cells. …”
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20237
Table 1_Optimization of Artemisia ordosica crude polysaccharides on milk fatty acid composition in lactating donkeys and their effects on rectal microbiome and lactation performanc...
Published 2025“…</p>Methods<p>A single-factor completely randomized design was used, with 14 lactating Dezhou donkeys (6.16 ± 0.67 years old, 250.06 ± 25.18 kg, parity 2.82 ± 0.48, 39.11 ± 7.42 days in lactation, each with a foal) randomly divided into two groups (n = 7/group). …”
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20238
Negative Activation Volume in Hydrated BaZr<sub>0.8</sub>Y<sub>0.2</sub>O<sub>3−δ</sub> Proton Conductor at Room Temperature (Supporting Information)
Published 2025“…A piston cylinder apparatus is used, with boron nitride (BN) powder as the pressure medium. …”
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20239
Raw data of this work.
Published 2024“…At the individual level, baseline positive identity and general positive youth development significantly increased persistent non-depression at T2 and T3. …”
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20240
<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b>
Published 2025“…</p><p dir="ltr">Our results suggest that the increase in cytosolic Ca<sup>2+</sup> elicited by HlyA impacts RBCs’ circulation by decreasing RBCs’ deformability and increasing spleen retention. …”