Data Sheet 3_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx by Maria Jordan (10265489)

“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”

DataSheet1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.csv by Mengshi Zhao (20157978)

“…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …”

Image 2_Biometric parameters and choroidal microstructure in Chinese children with unilateral anisometropia.pdf by Jing Wen (25059)

“…The TCA and LA were significantly greater in hyperopic eyes and significantly lower in myopic eyes compared to normal eyes (all p <0.005). …”

Data Sheet 2_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Discussion<p>The capacity for infectious disease prevention and control among Guangxis grassroots hospital physicians has significantly improved following COVID-19. The high engagement in related training and emergency response efforts reflects a strong sense of professional identity and commitment. …”

<b>Single-cell landscape of piglet lung response with </b><b><i>Actinobacillus pleuropneumoniae</i></b> by Junhui Zhu (12532423)

“…In contrast, epithelial cells were significantly decreased and included those with features of epithelial-mesenchymal transition differentiated into fibroblasts through the signalling of TGFB1 and HIF1A. …”

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”

Image 4_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif by Jorgo Lika (21189020)

“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”

Table 2_Leucocalocybe mongolica inoculation enhances rice growth by reallocating resources from flavonoid defense to development via MYB/bHLH/WRKY networks.xlsx by Mingzheng Duan (11630632)

“…However, total flavonoid content decreased at the highest LY9 concentration, suggesting a metabolic trade-off between growth promotion and secondary metabolite production. …”

Data Sheet 1_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.pdf by Chaomin Meng (21496829)

“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”

Data Sheet 2_Red mite (Panonychus citri) attack amplifies citrus rootstock-driven responses in physiological and biochemical traits, VOC emission, and expression of defence-related... by Tommy Rioja (22179742)

“…<p>Citriculture faces significant constraints in expanding into new environments and agroecological zones. …”

Image 1_Comparative analysis of gut microbiota in metabolic syndrome and obese children from Southeastern China.jpeg by Jingjing Wang (140791)

“…At the class and genus levels, we found that the relative abundance of c_Gammaproteobacteria increased with weight, whereas c_Bacteroidia and g_Bacteroides decreased. Notably, g_Faecalibacterium was significantly less abundant in the MS group compared to the other cohorts. …”

Data Sheet 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Data Sheet 2_Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication.pdf by Yarou Gao (20620991)

“…In a mouse model of lethal influenza, isoxsuprine significantly decreased lung viral titers, mitigated pulmonary inflammation, and enhanced survival rates. …”

Table 1_Ambroxol attenuates detrimental effect of LPS-induced glia-mediated neuroinflammation, oxidative stress, and cognitive dysfunction in mice brain.xlsx by Safi Ullah (18598897)

“…Ambroxol treatment (30 mg/kg/day for 14 days) significantly reduced neuroinflammation and oxidative stress compared to LPS-treated mice. …”

Table 1_Impact of in-hospital COVID-19 quarantine policy changes on quality of acute stroke care: a single center experience.docx by Minkyung Kim (741928)

“…However, after accounting for potential confounders, a significant delay in DIT was found to be associated with the in-hospital COVID-19 quarantine policy.…”

DataSheet3_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.xlsx by Marek Sierzega (3846406)

“…However, the analysis of paired samples failed to demonstrate a decreasing concentration gradient between the portal and peripheral blood for any of the myokines, evidencing against their release by the primary tumour. …”

Data_Sheet_2_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.pdf by Weiran Lv (715679)

“…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …”

Data Sheet 1_The impact of salt-tolerant plants on soil nutrients and microbial communities in soda saline-alkali lands of the Songnen plain.docx by Junjie Song (4400227)

“…Introduction<p>Soil salinization poses a significant threat to agricultural development and ecosystem health. …”

Image 1_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif by Jorgo Lika (21189020)

“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”