DataSheet1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic... by Boris Jakopovic (9265517)

“…Even with treatment advancements, the survival rates for these patients remain suboptimal. There is a significant focus on developing multi-targeted therapies due to the common issue of drug resistance in standard and targeted cancer treatments. …”

Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study by Emiko Otsuka (7519313)

“…Here, we retrospectively analyzed thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels in 51 patients (mean age: 72.3 ± 10.7 years; 58.8% male) undergoing hemodialysis before, during, and after halting roxadustat treatment. TSH levels were significantly decreased from a median of 2.46 (interquartile range:1.60–4.51) mU/L before roxadustat treatment to 1.36 (0.72–2.41) mU/L during treatment (<i>p</i> < 0.001), and improved to 2.56 (1.78–4.63) mU/L after halting roxadustat (<i>p</i> < 0.001). …”

Suppl. Figure 1, García-Ortuño, et al. by NORMA A. Bobadilla (22642043)

“…<p dir="ltr">During gestation period, all pregnant rats showed a significant increase in BW from day 15 onward, however, in the CC and CR groups, this increase was already evident from the day 10. …”

Critical period EB odorant experience via Or42a neurons specifically elevates VM7 serotonin signaling. by Vanessa Kay Miller (19775496)

“…Two-way ANOVA with Tukey’s multiple comparisons show a significant increase in serotonin (<i>n</i> = 12/condition, <i>p</i> = 7.13 × 10⁻⁵) and a significant decrease in VM7 innervation (<i>n</i> = 12/condition, <i>p</i> = 4.78 × 10⁻¹⁰) with EB experience. …”

Data Sheet 1_Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.pdf by Elena Campione (8906858)

“…Finally, improvements in clinical scores i.e., PASI, NAPSI, DLQI, itch VAS, PAIN VAS, scPGA and sPGA-G and biochemical serum profile, as well as a significant decrease in serum IL-17A, TGF-β 1 and IL-10 levels (from 8.51 to 4.16 pg/mL; from 66.10 to 48.70 ng/mL and from 20.05 to 14 pg/mL, respectively) were observed in all patients.…”

Image 4_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…In parallel, spectral imaging further revealed post-treatment shifts in macrophage populations, with a significant decrease in inflammatory subsets (CD14+, CD14+/Mac387+, p<0.05) and an increase in anti-inflammatory subsets (CD16+, CD16+/CD163+, CD16+/CD68+, p<0.05). …”

Image 2_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…In parallel, spectral imaging further revealed post-treatment shifts in macrophage populations, with a significant decrease in inflammatory subsets (CD14+, CD14+/Mac387+, p<0.05) and an increase in anti-inflammatory subsets (CD16+, CD16+/CD163+, CD16+/CD68+, p<0.05). …”

Table1_Cognitive performance in ISS astronauts on 6-month low earth orbit missions.docx by Sheena I. Dev (20293434)

“…There was slowed performance observed in early flight on tasks of processing speed, visual working memory, and sustained attention. We observed a decrease in risk-taking propensity during late flight and post-flight mission phases. …”

Table_1_Spatiotemporal variation in grain production performance and efficiency of the cultivated landscapes in Upper Blue Nile Basin of Ethiopia: the impact of residual moisture-b... by Tibebu Kassawmar (5120267)

“…The results show that only 39% of the basin is currently cultivated, although a significant cropland expansion (10%) was recorded between 1985 and 2020. …”

Table 5_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”

Image 1_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…In parallel, spectral imaging further revealed post-treatment shifts in macrophage populations, with a significant decrease in inflammatory subsets (CD14+, CD14+/Mac387+, p<0.05) and an increase in anti-inflammatory subsets (CD16+, CD16+/CD163+, CD16+/CD68+, p<0.05). …”

Image 1_Comparative analysis of cranberry fruit rot fungal diversity in Massachusetts from wild, organic, and conventional ecosystems using multiplex PCR.jpg by Salisu Sulley (22059035)

“…Organic bogs exhibited a significant decline in species richness from 6 fungi in 2021 to 2 fungi in 2022. …”

Global, regional and national burden of colorectal cancer and its risk factors, 1990-2021: a systematic analysis for the GBD 2021 by Xuan Zeng (22461799)

“…<p dir="ltr"><b>Importance: </b>Colorectal cancer (CRC) constitutes a significant segment of the global cancer burden, thereby warranting an in-depth epidemiological appraisal to inform strategic public health interventions and resource allocation. …”

Image_3_Spatiotemporal variation in grain production performance and efficiency of the cultivated landscapes in Upper Blue Nile Basin of Ethiopia: the impact of residual moisture-b... by Tibebu Kassawmar (5120267)

“…The results show that only 39% of the basin is currently cultivated, although a significant cropland expansion (10%) was recorded between 1985 and 2020. …”

Supplementary Material for: Effect of Surface Perturbation Treadmill Training Program on Strategies and Kinematics of Reactive Stepping during Standing in Older Adults: A Single-Bl... by figshare admin karger (2628495)

“…Results: Both groups showed a significant decrease in the percentage of multiple-step responses (p=0.013) and a shorter total recovery time to recover balance (p=0.006). …”

Image1_Cognitive performance in ISS astronauts on 6-month low earth orbit missions.pdf by Sheena I. Dev (20293434)

“…There was slowed performance observed in early flight on tasks of processing speed, visual working memory, and sustained attention. We observed a decrease in risk-taking propensity during late flight and post-flight mission phases. …”

Image 5_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…In parallel, spectral imaging further revealed post-treatment shifts in macrophage populations, with a significant decrease in inflammatory subsets (CD14+, CD14+/Mac387+, p<0.05) and an increase in anti-inflammatory subsets (CD16+, CD16+/CD163+, CD16+/CD68+, p<0.05). …”

Table 2_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”

Image_4_Spatiotemporal variation in grain production performance and efficiency of the cultivated landscapes in Upper Blue Nile Basin of Ethiopia: the impact of residual moisture-b... by Tibebu Kassawmar (5120267)

“…The results show that only 39% of the basin is currently cultivated, although a significant cropland expansion (10%) was recorded between 1985 and 2020. …”

Supplementary file 1_Exposure-response analyses of venetoclax combined with hypomethylating agents in myelodysplastic syndromes: a retrospective study.docx by Ji-Xin Tian (21710993)

“…The use of azole antifungals was a significant factor influencing VEN concentration (P < 0.05). …”