First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> by Bingjie Hu (10835565)

“…Further mechanistic investigations reveal that the Omicron subvariant is ineffective in using TMPRSS2 compared with ancestral SARS-CoV-2 (HKU-001a) and previous variants, which may contribute to its decreased replication in Calu3 and Caco2 cells. In K18-hACE2 transgenic mice, the replication capacity of the Omicron subvariant is significantly attenuated in both the upper and lower respiratory tracts of virus-infected animals when compared to that of the ancestral strain and Delta (B.1.617.2) variant, correlating with substantially ameliorated lung pathology. …”

Related to Fig 3. by Mohammad Nafees Ansari (22232505)

“…(<b>K–N</b>) Absolute quantification (mean ± SEM, <i>n</i> = 3–4) of GM3 (K), GD3 (L), GM2 (M), and GM1 (N) gangliosides shows an increase of GD3 and GM2 gangliosides and a decrease of GM3 and GM1 gangliosides in BT-474_ZFX^OE cells. …”

Investigating the effects of ankle foot orthoses on electromyography in impaired populations: a systematic review by Sally Kenworthy (20873172)

“…</p><p>Longitudinal studies refute concerns about adverse effects on EMG activity with prolonged AFO use, challenging the notion of decreased muscle activation and supporting the safety of extended AFO utilization.…”

Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (<i>N</i> = 19) by Carlijn de Roos (8061239)

“…</p><p>The findings also show a significant reduction in emotional and behavioural problems as well as parenting stress.…”

Transcriptional profiling of genes related to NET release and different types of cell death and phagocytosis in C57BL/6 (B6) versus BALB/c (B/c). by Thiago DeSouza-Vieira (4069615)

“…The adjusted p-value (adj. p-value) was set to differentiate significant differential probes from non-significant. …”

Table 4_Morphological and quantitative CT features of anterior mediastinal lesions in TAFRO syndrome and idiopathic multicentric Castleman disease.xlsx by Lamiaa Mohamed (21672566)

“…The CT values showed significant intergroup differences, with ROC analyses confirming high diagnostic accuracy for distinguishing the TAFRO without iMCD/iMCD-TAFRO group from the other groups. …”

Table 3_Morphological and quantitative CT features of anterior mediastinal lesions in TAFRO syndrome and idiopathic multicentric Castleman disease.xlsx by Lamiaa Mohamed (21672566)

“…The CT values showed significant intergroup differences, with ROC analyses confirming high diagnostic accuracy for distinguishing the TAFRO without iMCD/iMCD-TAFRO group from the other groups. …”

Table 1_Morphological and quantitative CT features of anterior mediastinal lesions in TAFRO syndrome and idiopathic multicentric Castleman disease.xlsx by Lamiaa Mohamed (21672566)

“…The CT values showed significant intergroup differences, with ROC analyses confirming high diagnostic accuracy for distinguishing the TAFRO without iMCD/iMCD-TAFRO group from the other groups. …”

Table 2_Morphological and quantitative CT features of anterior mediastinal lesions in TAFRO syndrome and idiopathic multicentric Castleman disease.xlsx by Lamiaa Mohamed (21672566)

“…The CT values showed significant intergroup differences, with ROC analyses confirming high diagnostic accuracy for distinguishing the TAFRO without iMCD/iMCD-TAFRO group from the other groups. …”

Data Sheet 1_Global, regional, and national trends and burden of hypertensive disorders in pregnancy among women of childbearing age from 1990 to 2021.pdf by Zhongyun Tang (21287855)

“…Background<p>Hypertensive disorders of pregnancy (HDP) are a significant cause of maternal and perinatal morbidity and mortality worldwide. …”

Table 1_Global, regional, and national trends and burden of hypertensive disorders in pregnancy among women of childbearing age from 1990 to 2021.xlsx by Zhongyun Tang (21287855)

“…Background<p>Hypertensive disorders of pregnancy (HDP) are a significant cause of maternal and perinatal morbidity and mortality worldwide. …”

Table 1_Relationship between nocturia, depression, and cognitive function and the mediating effects of nutritional indexes in older adults: data from NHANES 2011–2014.docx by Yin Xu (159474)

“…Thus, improving nutrition may decrease the risk of nocturia in older adults.</p>…”

<b>Metabolic shifts in ratio of ucOcn to cOcn towards bone resorption contribute to age-dependent bone loss in male mice</b> by Bin Wang (16631220)

“…Our findings further demonstrated that the increase in osteoclast activity and the decrease in osteoblast function were significantly corelated with blood levels of ucOcn and cOcn, respectively. …”

Table 1_Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide.docx by Junyong Wang (3807964)

“…The half-life of YTP in plasma is significantly longer than that of YW12D and TP5. YTP also displays an improved ability to protect the host from CTX-induced weight loss and thymus and spleen indices decrease than YW12D and TP5. …”

Urbanization and climate jointly shape the composition of plant life forms by Zhiwen Gao (19941582)

“…The compositions of plant life forms were significantly controlled by urbanization intensity and annual mean temperature. …”

Table 1_The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.docx by Liuzhen Yang (20449762)

“…The results showed a significant decrease in fasting blood glucose levels (SMD = −0.79, 95% CI: −1.11 to −0.46). …”

Supplementary file 1_Differential adaptations of japonica rice to submergence stress during the tillering stage under various seedling cultivation and transplanting methods.docx by Sumei Duan (18711099)

“…Over two-thirds of tillers survived under complete submergence for up to 7 days during the tillering stage. Submergence significantly affected POD and SOD activities, MDA and PRO contents, and SPAD values, characterized by initial increases followed by decreases in antioxidant enzyme activities, MDA accumulation, and PRO content elevation. …”