يعرض 20,081 - 20,100 نتائج من 23,503 نتيجة بحث عن '(( significant ((challenges decrease) OR (challenges case)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.50s تنقيح النتائج
  1. 20081

    Data Sheet 1_A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis.pdf حسب Lauren Stewart Stafford (17937497)

    منشور في 2025
    "…</p>Results<p>Following SOCS1-KIR pretreatment, cell proliferation significantly decreased in control, but not ERU-derived PBMCs. …"
  2. 20082

    Table 1_Genetic diversity and antibiotic resistance of Mycobacterium bovis in bovines in the Delta area of Egypt.docx حسب Mohamed Sabry A. Elsayed (22235200)

    منشور في 2025
    "…Introduction<p>Mycobacterium bovis (M. bovis) causes significant financial harm to the cattle industry through decreased productivity and trade limitations, while also posing a risk to human health through zoonotic transmission, which is primarily from unpasteurized milk or close animal contact.…"
  3. 20083

    Image 1_Clinical study of PLA2R epitope spreading for predicting proteinuria remission in primary membranous nephropathy.pdf حسب Xueyang Cheng (22473883)

    منشور في 2025
    "…In the RTX group, epitope spreading significantly decreased at M6 (P = 0.004), and four patients (22.2%) with no clinical remission were ARA-positive. …"
  4. 20084

    Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  5. 20085

    Replication package for "Measuring trade costs and analyzing the determinants of trade growth between Cambodia and major trading partners: 1993-2019" حسب Borin Keo (20919743)

    منشور في 2025
    "…Despite their practical significance and increasing policy attention in the country, little is known about these costs.…"
  6. 20086

    Table 1_Glucose and lipid metabolism in non-diabetic, non-obese patients with obstructive sleep apnea: sex differences.docx حسب Yuhan Wang (595964)

    منشور في 2025
    "…The high-density lipoprotein cholesterol (HDL-C) level in OSA participants was significantly lower (0.99 vs. 1.12 mmol/L, p = 0.036), and the triglyceride-glucose (TyG) index was significantly higher (8.74 vs. 8.45, p = 0.016), while there was no significant difference in the levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and non-HDL-C. …"
  7. 20087

    DataSheet1_Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.doc حسب Guojun Lu (7169969)

    منشور في 2024
    "…Background<p>T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. …"
  8. 20088

    Patient characteristics. حسب Youssef Hbid (18803761)

    منشور في 2025
    "…<div><p>Background and aim</p><p>The COVID-19 pandemic imposed significant pressures on healthcare services such as stroke care. …"
  9. 20089

    Table 1_A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis.docx حسب Lauren Stewart Stafford (17937497)

    منشور في 2025
    "…</p>Results<p>Following SOCS1-KIR pretreatment, cell proliferation significantly decreased in control, but not ERU-derived PBMCs. …"
  10. 20090

    Table4_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  11. 20091

    Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  12. 20092

    Table1_Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.docx حسب Guojun Lu (7169969)

    منشور في 2024
    "…Background<p>T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. …"
  13. 20093

    Image2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.tif حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  14. 20094

    Data Sheet 1_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx حسب Stephanie Dauth (13274397)

    منشور في 2025
    "…Significant between-group differences were observed for changes in some parameters at day 4 (e.g., IL-10) and day 14. …"
  15. 20095

    Table 1_Prior Trichinella spiralis infection protects against Schistosoma mansoni induced hepatic fibrosis.docx حسب Asmaa M. El-kady (16502930)

    منشور في 2024
    "…Furthermore, pre- infection with T. spiralis markedly reduced S. mansoni- induced hepatic fibrosis, as evidenced by decreased collagen deposition, low expression of α-SMA, and significantly reduced levels of IL-17, IL-1B, IL-6, TGF-B, IL-23, and TNF-α compared to mice infected with S. mansoni only.…"
  16. 20096

    Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  17. 20097

    Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  18. 20098
  19. 20099

    Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study حسب figshare admin karger (2628495)

    منشور في 2025
    "…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …"
  20. 20100

    Data Sheet 4_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... حسب Yu Zhang (12946)

    منشور في 2025
    "…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …"