Showing 20,121 - 20,140 results of 23,503 for search '(( significant ((challenges decrease) OR (challenges case)) ) OR ( significant decrease decrease ))', query time: 0.49s Refine Results
  1. 20121

    Repetitive stress modulates loudness perception. by Ghattas Bisharat (20706928)

    Published 2025
    “…Mice exhibited increased perceptual boundaries during repeated stress, indicating a decreased loudness perception (<i>t</i> test, <i>p</i> = 1.2 × 10<sup>−05</sup>, mean ± SE). …”
  2. 20122

    Data Sheet 1_Real world evidence of dupilumab effectiveness in a Colombian cohort of patients diagnosed with severe asthma.docx by Abraham Alí-Munive (21347201)

    Published 2025
    “…FEV<sub>1</sub>pp showed higher but not significant values from the 2–4-month period, with a median change of 12.5% (IQR: 0.3, 21.5). …”
  3. 20123

    Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

    Published 2025
    “…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”
  4. 20124

    Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx by Johnny Amer (495285)

    Published 2025
    “…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”
  5. 20125

    Correlation analyses between studied genes. by Marwa A. Ali (11973086)

    Published 2024
    “…</p><p>Conclusions</p><p>Our study is the first to detect decreased <i>NEAT-1</i> and <i>miR374b-5p</i> expression in COVID-19 patients’ serum. …”
  6. 20126

    Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

    Published 2024
    “…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”
  7. 20127

    Table 1_Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks.docx by Chen Shaopeng (20576303)

    Published 2025
    “…Introduction<p>The gut microbiota significantly influences the host’s production performance and health status, with different gastrointestinal tissues exhibiting functional diversity reflected in their microbial diversity.…”
  8. 20128

    Table 3_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

    Published 2025
    “…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”
  9. 20129

    Supplementary Material for: The current status of tumor markers as biomarkers in the era of immunotherapy for hepatocellular carcinoma: alpha-fetoprotein alone is not sufficient by Hiraoka A. (4273894)

    Published 2025
    “…Positive rates for AFP (67.8%, 62.1%, 50.8%, respectively) and DCP (84.1%, 80.5%, 72.7%, respectively) were decreased (each P<0.001), while the AFP-L3 rate did not show a significant change (54.4%, 57.7%, 51.9%, respectively P=0.390). …”
  10. 20130
  11. 20131

    Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx by Ping Zhao (47228)

    Published 2025
    “…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19<sup>+</sup> B cells and CD14<sup>+</sup> monocytes, but significantly decreased on CD56<sup>+</sup> NK cells.We identified a distinct CD226<sup>+</sup>CD19<sup>+</sup> B cell subset that exhibited pathogenic features in pSS. …”
  12. 20132

    Table 1_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx by Jianwei Hong (6918776)

    Published 2025
    “…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
  13. 20133

    Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

    Published 2024
    “…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”
  14. 20134

    Effects of extracorporeal shock wave therapy on motor function in patients with cerebral palsy: a systematic review and meta-analysis by Hui-Hui Peng (21503736)

    Published 2025
    “…In addition, spasticity significantly decreases, particularly with focused ESWT or ESWT targeting the upper limbs.…”
  15. 20135

    Table 2_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

    Published 2025
    “…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”
  16. 20136

    SNAP-25 (1-197) binds to syntaxin-1A, and the interaction is enhanced by Ser187 phosphorylation. by Dilara Koc (22431017)

    Published 2025
    “…<b>(C and D)</b> PMA treatment further decreases neurotransmitter release when a low level of SNAP-25 cleavage is present. …”
  17. 20137

    Supplementary file 2_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

    Published 2025
    “…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …”
  18. 20138

    Table 4_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx by Jianwei Hong (6918776)

    Published 2025
    “…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
  19. 20139

    Broader frequency tuning in auditory cortex of <i>Fmr1</i> KO rats despite unaltered subcortical tuning properties. by D. Walker Gauthier (21637726)

    Published 2025
    “…**<i>p</i> < 0.01, ***<i>p</i> < 0.0001, ns = not significant. Data and code underlying this figure can be found at <a href="http://doi.org/10.5281/zenodo.15559344" target="_blank">http://doi.org/10.5281/zenodo.15559344</a>. …”
  20. 20140

    The role of SLMO in the PSS/PISD pathway. by Siwen Zhao (543384)

    Published 2024
    “…(C) SLMO overexpression failed to reverse decreased mitochondrial size from <i>pisd</i><sup><i>RNAi</i></sup> lines. …”