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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
challenges case » challenges pose (Expand Search), challenges raised (Expand Search), challenges faced (Expand Search)
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19081
Data Sheet 1_Highly pathogenic bovine viral diarrhea virus BJ-11 unveils genetic evolution related to virulence in calves.docx
Published 2025“…<p>Bovine viral diarrhea virus (BVDV) is the causative agent of bovine viral diarrhea, which causes significant economic loss to the global livestock industry. …”
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19082
Image 6_The burden of atrial fibrillation/atrial flutter in Europe from 1990 to 2021, with a forecast of incidence through 2044.tif
Published 2025“…</p>Conclusion<p>Despite substantial efforts to manage AF/AFL in Europe, it remains a significant public health challenge. The burden of AF/AFL varies considerably across European countries and subregions, as well as between different EU classifications (EU-28 vs. …”
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19083
Image 2_The burden of atrial fibrillation/atrial flutter in Europe from 1990 to 2021, with a forecast of incidence through 2044.tif
Published 2025“…</p>Conclusion<p>Despite substantial efforts to manage AF/AFL in Europe, it remains a significant public health challenge. The burden of AF/AFL varies considerably across European countries and subregions, as well as between different EU classifications (EU-28 vs. …”
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19084
A Protocol for a Scoping Review identifying Barriers and Facilitators to follow Lifestyle Interventions in Mild Cognitive Impaired Participants living in Scandinavia
Published 2025“…A growing body of evidence suggests that the etiology of dementia is closely associated with modifiable lifestyle factors, and that nearly half of future dementia cases worldwide could potentially be prevented. Nevertheless, sustaining long-term lifestyle modifications poses a significant challenge – particularly among older adults with cognitive impairments.…”
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19085
Table 1_MYB Proto-Oncogene Like 2 identified as a biomarker for uterine corpus endometrial carcinoma: evidence from bioinformatics and clinical validation.docx
Published 2025“…Background<p>Endometrial carcinoma (EC) is the sixth most prevalent malignancy among women globally, posing a significant clinical challenge due to limited therapeutic options for advanced or recurrent cases. …”
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19086
Image 1_The burden of atrial fibrillation/atrial flutter in Europe from 1990 to 2021, with a forecast of incidence through 2044.tif
Published 2025“…</p>Conclusion<p>Despite substantial efforts to manage AF/AFL in Europe, it remains a significant public health challenge. The burden of AF/AFL varies considerably across European countries and subregions, as well as between different EU classifications (EU-28 vs. …”
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19087
Data Sheet 1_Projecting temperature-related dengue burden in the Philippines under various socioeconomic pathway scenarios.docx
Published 2024“…Between 2010-2019, 72.1% of reported dengue cases in the Philippines were attributable to temperature, demonstrating that temperature is a significant driver in dengue transmission. …”
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19088
Data Sheet 1_The burden of atrial fibrillation/atrial flutter in Europe from 1990 to 2021, with a forecast of incidence through 2044.docx
Published 2025“…</p>Conclusion<p>Despite substantial efforts to manage AF/AFL in Europe, it remains a significant public health challenge. The burden of AF/AFL varies considerably across European countries and subregions, as well as between different EU classifications (EU-28 vs. …”
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19089
Image 4_The burden of atrial fibrillation/atrial flutter in Europe from 1990 to 2021, with a forecast of incidence through 2044.tif
Published 2025“…</p>Conclusion<p>Despite substantial efforts to manage AF/AFL in Europe, it remains a significant public health challenge. The burden of AF/AFL varies considerably across European countries and subregions, as well as between different EU classifications (EU-28 vs. …”
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19090
Data Sheet 1_HLA-DR expression in cytotoxic T lymphocytes: a key to boost the therapeutic potential of T cell-based strategies for breast cancer.docx
Published 2025“…<p>T cell-based therapies, involving ex vivo expansion of patients’ T lymphocytes, hold significant promise for chemotherapy resistant cases of breast cancer (BC), although their effectiveness remains challenging. …”
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19091
Data Sheet 1_Genomic epidemiology of a novel Pandoraea pneumonica group caused severe bloodstream infection in Hainan, China, 2021-2024.zip
Published 2025“…</p>Conclusion<p>BSI caused by this novel cluster of P. pneumonica is linked to significant morbidity and mortality. Such cluster remains a critical public health challenge due to their regional epidemiological patterns and antibiotic treatment risk. …”
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19092
Supplementary Material for: Diagnostic yield of updated indications for endomyocardial biopsy and its clinical predictors in a Chinese cohort
Published 2025“…The higher yield (52.8%) was found in clinically suspected myocarditis while no significant difference between cases with and without acute unstable hemodynamics (66.7% vs 47.1%; P=0.130). …”
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19093
Table 6_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”
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19094
Data Sheet 2_The Emotional Recession: global declines in emotional intelligence and its impact on organizational retention, burnout, and workforce resilience.pdf
Published 2025“…</p>Results<p>Global EQ scores declined by 5.79% (Cohen’s d = 0.22, 95% CI [0.17, 0.27]), with statistically significant decreases across all eight competencies (p < 0.001). …”
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19095
Classification of land use index.
Published 2025“…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …”
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19096
Supplementary Figure S2 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone
Published 2025“…Human PCa cells marked by Ku70 were significantly decreased after 30 days of treatment by intraperitoneal injection with batiraxcept (20 mg/kg/QOD, n = 8–9, docetaxel (10 mg/kg/QW, n = 9) or the combination of batiraxcept (20 mg/kg/QOD, n = 9) and docetaxel (10 mg/kg/QW, n = 9) compared to vehicle controls (n = 8,10). …”
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19097
Data Sheet 1_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.docx
Published 2025“…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …”
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19098
Data Sheet 1_Association of body roundness index with cardiovascular disease in patients with cardiometabolic syndrome: a cross-sectional study based on NHANES 2009-2018.pdf
Published 2025“…For CVD, stratified analyses did not show significant difference between strata. For CHF, BMI interacted with the association, with BRI being associated with decreased risk of CHF in a subgroup of normal weight subjects and increased risk of CHF in a subgroup of obese subjects. …”
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19099
Image3_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
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19100
Image4_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif
Published 2025“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”