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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury
Published 2021“…Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …”
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The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells
Published 2021“…It also significantly increased Bax/Bcl2 ratio and PERK levels without affecting caspase-3 expression. …”
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Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report
Published 2018“…The NY-ESO-1-specific T cells response of the patient was found to be increased after the third and the fifth (**p = 0.002) cycles of treatment but had a significant decline after progression (**p = 0.0028). …”
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Proteome analysis of Candida albicans cell wall mutants. (c2011)
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Transferrin‑modifed liposomes triggered with ultrasound to treat HeLa cells
Published 2021“…Calcein uptake by HeLa cells was found to be significantly higher with the Tf-PEG liposomes compared to the non-targeted control liposomes. …”
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Experimental and numerical study of different metal contacts for perovskite solar cells
Published 2023“…The computational analysis confirms that screening of suitable metal back contact is necessary to increase device performance and stability significantly.…”
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A photoactivatable chemotherapeutic Ru(II) complex bearing bathocuproine ligand efficiently induces cell death in human malignant melanoma cells through a multi-mechanistic pathway
Published 2021“…A significant increase in ROS production and DNA damage was also observed. …”
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Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis
Published 2024“…No significant changes were observed on IOP with mannitol administration when comparing vitrectomized versus non- vitrectomized eyes.…”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…When compared to control specimens, evaluation of epigenetic alterations in rat tumor cells in vivo showed significant dose-dependent decrease in lysine methylation status of H3K4m3 and H3K9m3 and dose-dependent increase in lysine acetylation in H4K16ac levels (H4K20m3 was not changed) in treated groups. …”
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Comparison of Myeloid Cells in Circulation and in the Tumor Microenvironment of Patients with Colorectal and Breast Cancers
Published 2017“…We found that both PBC and CRC patients have significantly higher levels of granulocytic and immature myeloid cells in the TME. …”
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Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury
Published 2021“…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development
Published 2021“…The aim is to look for significant differences in the behaviour of the CL/P patient-derived cells in vitro when compared to control cells from the healthy donor through the study of different mechanisms, including cell proliferation, cell migration and adhesion. …”
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Amniotic stem cells as a source of regenerative medicine to treat female infertility
Published 2022“…Despite the technological developments to treat infertility, the global infertility rate is increasing significantly. Many infertility conditions are currently treated using various advanced clinical approaches such as intrauterine semination (IUI), in vitro fertilization (IVF), and intracytoplasmic injection (ICSI). …”
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Sesamum indicum (sesame) enhances NK anti-cancer activity, modulates Th1/Th2 balance, and suppresses macrophage inflammatory response
Published 2020“…The secretion of key pro-inflammatory mediators (IL-6, TNFα, and nitric oxide) by primary macrophages was significantly inhibited by Sesamum indicum. Moreover, Sesamum indicum increased the cytotoxic activity of NK cells against YAC-1 tumor cells. …”
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Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
Published 2010“…Rationale: Vascular endothelial growth factor receptor (VEGFR) inhibition increases ceramides in lung structural cells of the alveolus, initiating apoptosis and alveolar destruction morphologically resembling emphysema. …”
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Cactus-like nanothorn photoanodes for enhancing dye-sensitized solar cell efficiency
Published 2025“…The cactus-like nanothorn photoanode achieved a significantly higher PCE of 8.3% compared to the 2.9% of the unmodified nanoflower structure. …”
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The antiproliferative and pro-apoptotic effect of kefir on human leukemic cell lines. (c2008)
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The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion
Published 2020“…Additionally, cells treated with LT showed an increase in adhesion, decrease in invasion across a collagen matrix, and in increase in Rho A activation. …”
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