The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013) حسب Zgheib, Perla Z.

"…The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. In addition, a decrease in CDC42 activation levels, and an increase in Rac activation were detected. …"
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Sternbergia Clusiana Bulb Ethanolic Extracts Induce Apoptosis in MCF-7 Breast Cancer Cells حسب Elias, Nazira

"…A dose-dependent increase in apoptosis via induced DNA fragmentation was revealed via Cell Death ELISA as well as an increase in cellular fragmentation using flow cytometry. …"
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Phospholipase C negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells حسب El-Sibai, Mirvat

"…The Rho GTPases Rac and Cdc42 play a central role in the regulation of secretory and cytoskeletal responses in antigen-stimulated mast cells. In this study, we examine the kinetics and mechanism of Rac and Cdc42 activation in the rat basophilic leukemia RBL- 2H3 cells. …"
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FoxP3⁺ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets حسب Reem Saleh (3513056)

"…<p dir="ltr">T Regulatory cells (Tregs) can have both protective and pathological roles. …"

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …"
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Measuring Sustainability in Design for Hospitality حسب Zimmer, Teresa Marie

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Investigation of an integrated hydrogen production system based on nuclear and renewable energy sources: Comparative evaluation of hydrogen production options with a regenerative f... حسب Orhan, Mehmet Fatih

"…Hydrogen production via water decomposition is a potential process for direct utilization of nuclear thermal energy to increase efficiency and thereby facilitate energy savings. …"
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030) حسب Khaled F. Alkaraki (22051967)

"…<p dir="ltr">Modeling the impacts of Land Use/Land Cover changes (LULCC) on Land Surface Temperature (LST) is crucial in understanding and managing urban heat islands, climate change, energy consumption, human health, and ecosystem dynamics. …"

Effects of recording food intake using cell phone camera pictures on energy intake and food choice حسب Doumit, Rita

"…Results from the focus group indicated a positive attitude toward the use of cell phone pictures in recording food intake and an increased awareness of food choice and portion size. …"
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Novel Whole-Cell Inactivated Neisseria Gonorrhoeae Microparticles as Vaccine Formulation in Microneedle-Based Transdermal Immunization حسب Rikhav Gala (18069364)

"…Here we report that whole-cell-based gonococcal microparticle vaccine loaded in dissolvable microneedles for transdermal administration induced significant increase in antigen-specific IgG antibody titers and antigen-specific CD4 and CD8 T lymphocytes in mice compared to gonococcal antigens in solution or empty microneedles. …"

Evaluation of cell disruption methods for protein and coenzyme Q10 quantification in purple non-sulfur bacteria حسب Ojima Z. Wada (14155734)

"…However, due to PNSB’s peculiar cell envelope (e.g., increased membrane cross-section for energy transduction) and relatively smaller cell size compared to well-studied microbial protein sources like yeast and microalgae, the effectiveness of common cell disruption methods for protein quantification from PNSB may differ. …"

Giant cell tumour of the infra temporal fossa treated with denosumab in an elderly patient: A case report حسب Belal Alani (21323696)

"…Although Surgical resection remains the treatment of choice, its coupled with increase morbidity and recurrence. Here we present a case of elderly patient with infra temporal CGT treated with <u>Denosumab</u> and showed significant improvement in symptoms and <u>radiological findings.…"

Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway حسب Hodroj, Mohammad Hassan

"…Background Topotecan (TP) is an anticancer drug acting as topoisomerase I inhibitor that is used in the treatment of many types of cancers including leukemia, but it has significant side effects. Andrographolide, a compound extracted from Andrographis paniculata, was recently proven to inhibit the growth of cancer cells and can induce apoptosis. …"
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Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016) حسب Farhat, Stephanie Roy

"…The bis-bidentate complexes tested were four: Ru-I: [Ru(II)(1,10-phenanthroline)2Cl2]; Ru-II: [Ru(II)(4,7-diphenyl-1,10-phenanthroline)2Cl2]; Ru-III: [Ru(II)(4,7-diphenyl-1,10-phenanthroline-disulfonate)2Na2]2+ and Ru-IV: [Ru(II)(2,2'-bipyridine)2Cl2], along with their corresponding free ligands L-I, L-II, L-III and L-IV, respectively. Ru-II showed significant potency on most of the cell lines tested (5 out of 6), as well as Ru-I on two of them while the others were inert. …"
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Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data حسب Mohammed Toufiq (7251596)

"…<p dir="ltr">According to publicly available transcriptome datasets, the abundance of Annexin A3 (ANXA3) is robustly increased during the course of sepsis; however, no studies have examined the biological significance or clinical relevance of ANXA3 in this pathology. …"

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

"…Purpose Establishing the reliability of a new method to check the mean retinal and choroidal reflectivity and using it to find retinal and choroid changes in amblyopia. Methods Design: Retrospective case-control. …"
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<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells حسب Nouralhuda Alateyah (21363215)

"…TI significantly suppressed BC cell growth, inhibited migration and invasion and induced apoptosis. …"

Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes حسب Colleen A. Lopez (18520071)

"…In EHT, FAO was significantly higher than in monolayer cells or those on static scaffolds and could be further increased by culture with oleate and WY-14643. …"

Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…This has been associated with upregulation of MAC complex and increased level of cell lysis and apoptosis marked by downregulation of PI3K and upregulation of Annexin v and Caspase-3.…"

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

"…Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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